1EO0


Conserved Protein Domain Family
TFIIS_I

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cd00183: TFIIS_I 
Click on image for an interactive view with Cn3D
N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
Statistics
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PSSM-Id: 238107
Aligned: 29 rows
Threshold Bit Score: 55.007
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
putative RNA
Conserved site includes 5 residues -Click on image for an interactive view with Cn3D
Feature 1:putative RNA polymerase binding site [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1             ##  #                                                ##                 
1EO0_A      3 SKEVLVHVKNLEKNks---------nDAAVLEILHVLDKEfv-pTEKLLRETKVGVEVNKFKKstn-veISKLVKKMISS 71   baker's yeast
7486099   257 SADVANAKGFLAAKe----------eASICVDILALLMKFs--iISTAIETRRIMEKLERLTKhkd-rkICNAALALLHH 323  thale cress
4558668   274 AADVANAKGVLSGKp----------eVSRCIDALSLLMKIn--iTPKPKEPRRMMDKLEGLTKhkd-rkICHVASALLHL 340  thale cress
7486099    12 TDLPRLVSTAIRASnsqn-----asdVERCFDVLRYLKGLn--lSVKNLSHSKVILPLESLRDhen-pkIRTEAHVLFTS 83   thale cress
NP_199949  43 AAHVARDKGFYIVSp----------eAIQCVEILRHMRTLp--lNARLITKTDGLRVLLFLSKngn-pkIRSESKAVIDH 109  thale cress
4558668    20 LCDLTAAAIKATYNtrn------pceVERCIDVLNHLKSLs--lSVKDIRLSESIVKLETLRShrn-prIRKEAQALFHS 90   thale cress
2924782   164 SADFANAKGILASEv----------eTSMCVDTLTLLLEFp--iSARDMETRKLMVRLEHLTKhkn-rkICNSASKLLQC 230  thale cress
7486267    10 FEAALRAAKSVKGDens-------peVSRFVDAMNRLKEApkslVCDVVCKTSMGQGLEFFIDhkn-pkIRSEGRILRDL 81   thale cress
4506009    72 YKLLNNWLTYSKTTn----------nIPLLQQILLTLQHLp--lTVDHLKQNNTAKLVKQLSKssedeeLRKLASVLVSD 139  human
AAK70627   80 IKVKLVAVGGEDGSggggggtsadssEDAVVDLLRDLQAVp--mTFETLEASKISKTISGLRKhsssekVRRLAAALYKS 157  rice
Feature 1           
1EO0_A     72 WKDAIN 77   baker's yeast
7486099   324 WRQTIR 329  thale cress
4558668   341 WRQRIR 346  thale cress
7486099    84 WMKTFY 89   thale cress
NP_199949 110 WKSILH 115  thale cress
4558668    91 WLKTFY 96   thale cress
2924782   231 WRESIR 236  thale cress
7486267    82 WMKFFY 87   thale cress
4506009   140 WMAVIR 145  human
AAK70627  158 WKAIVD 163  rice

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