Conserved Protein Domain Family
THH1_TOM1-3_dom

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pfam06454: THH1_TOM1-3_dom 
THH1/TOM1/TOM3 domain
This domain is found in plant proteins including THH1/TOM1/TOM3 from Arabidopsis. TOM1 and TOM3 are transmembrane proteins necessary for the efficient multiplication of tobamoviruses. THH1 supports tobamovirus multiplication, but to a lesser extent than TOM1 and TOM3. Members containing this domain are part of the GPCR superfamily and involved in stress tolerance.
Statistics
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PSSM-Id: 399452
Aligned: 17 rows
Threshold Bit Score: 308.878
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDP05347      25 FPDWWKKAEQNEAFQTYSNYGIGAAYGLIGLVAFVQLLRLQLRVPEYGWTTQKVFHLLNCLVSVLRCSVFFFRPALEGLH 104
Q6EU03        11 GAGWWDLVNGSTAWQDGIFLSLAALYGLVAASSFIQVVRIQYRVPEYGWTTQKVFQLLNFIVNGARCSIFAVRRQVQQVN 90  Japanese rice
XP_001778362  21 IMDWWRRVDSSVLWQERIWLGLAIAYAVIAVIALVQLIRIELRVPEYGWTTQKVFHLLNFIVNGVRAAVFCFREDVQALS 100
EFJ23006      13 AEDWWYTLNESKAWQNRFYYSLSGAYLLVALVALIQLIRIEIRVPEYGWTTQKVFHLLNFLVNGVRAVVFFFRRQVQFLE 92 
XP_002979144  25 AKDWWEELNRSKSWQDGVFYALAALYAAIAIVALVQLIRIHRRVRDYGWTTQKVFHLLNFLVCAVRASVFLFRRPAQHVG 104
XP_011626514  41 ASDWWDEVQNSQKWQDGIFYALCAAYSAVAAVALIQLFRIQLRVPEYGWTTQKVFHLMNFIVNGLRAILFGFYRSVFLLK 120
XP_009419586 109 VQNWWDEMNDSSKWQDVVFYFLCAAYSLVSAVALIQVVRIQLRVPEYGWTTQKVFHFMNFIVNGVRAVVFGFHKNVFLFR 188
ERN19596      12 LQSWWTEINESSSWQDGIFFFLCAAYALVSAVALIQLIRIELRVPEYGWTTQKVFHFMNFIVNGVRAVVFGFHHQVFSFE 91 
EER97820      26 LRGWWDDVNESPQWQDAAFFSLAAAYALVSAVALIQLIRIQRRVPEFGWTTQKVFHLMNFLVNGVRALVFGFHAHVFLLH 105
Q9FEG2        20 ITSWWDDVNESTQWQDGIFFALCGAYALVSAVALVQLIRIQMRVPEYGWTTQKVFHLMNFVVNGVRAVLFGFHMQVFLVH 99  thale cress
EDP05347     105 PVVTKLMLLDLPGLLFFTTYTLLVLFWAEIYQQARNLPAAALRPTFLIINIVVYAVLAGLWALNAFGRTgdiqELAYTVS 184
Q6EU03        91 PEIFQHVILDLPGLAFFTTYAMLALFWAEISYQARGLETEGLRSGFYTINGVIYVIQVLLWALLWHNPN----PSMIVLS 166 Japanese rice
XP_001778362 101 PEILQHVLLDLPGILFFTTYTLLVLFWAEIYHQARSLSTDSLRPTFLITNAVIYLVQTFIWGYLYWSPS----VLVMSVA 176
EFJ23006      93 PRILQSLLLDLPGLLFFTTYTLLVLFWAEIYHQARSLPTDNLRPTFVVINTIIYTIQILVWLIVWWKPL----GLLESFS 168
XP_002979144 105 PHILQSFLLDLPGLLFFSTYTLLVLFWAEIFYQALSLPTENLRPSFLIINTAIYVFQIAIWLIQWWDPM----LVWDIFS 180
XP_011626514 121 PKVLQMVLLELPGLLFFSTYTLLVLFWAEIYHQARSLRIDRLRPAYLMINGAIYLLQVCIWIYVRVSPN----AVALEIA 196
XP_009419586 189 PRVFTLVLLDLPGILFFSTYTLLVLFWAEIYHQARSLPSDKLRIIYIIVNCGIYVIQVCIWIYLWIHDN----RIVESIG 264
ERN19596      92 PKVFRLVLLDLPVMLFFSTYTLLVLFWAEIYHQARSLPTDKLRIVYISINGGIYFIQVCIWIYLWIDDN----VVVESIG 167
EER97820     106 TKVYKLVLLDLPGLLFFSTYTLLVLFWAEIYHQARSLPTDKLRPAYIAVNTIIYVVQVCIWIYLGINDN----AVIELAS 181
Q9FEG2       100 PKALCWVLLDLPGLLFFSAYTLLVLFWAEIYHQARSLPTDKLRITYISVNVAVYLAQIGIWAYIWVHDN----STVELVG 175 thale cress
EDP05347     185 NLWLAAVFLAAAAGFLLYGGRLFVMLQRFPIESRGRRKKLREVGLVTSICAGCFTFRALMIATAAVDRdDLEVDMLGHPL 264
Q6EU03       167 KLFIAGLSFSAALGFLLYGGRLFFMLKRFPIESKGRQKKLREVGRVATICFLCFLARCIMMCFDAFDK-KADLDVLDHPI 245 Japanese rice
XP_001778362 177 KFFFAAVSLMAALGFLLYGGKLFLMLRRFPIESKGRRKKLREVGCVTAICFICFTIRSFIMTFSVFNK-AIDLDVLYHPI 255
EFJ23006     169 KIFFAGVSLGAAIGFLLYGGRLFLMLQRFPIESKGRRKKLREVGLVTAICFTCFTIRSGIMAWAAFDK-RGDLDVLDHPV 247
XP_002979144 181 RVFFAGVSFAGALGFLLYGGRLFLMLRRFPIESKGRRKKLREVGCVTAICFTCFTIRSVVVAWSAFDK-KAEIDVLYHPI 259
XP_011626514 197 KLFFAVVSFFAALGFLLYGGRLFFMLRRFPIESKGRRKKLNEVGFVTAICCTCFLIRCFMVAFSAFDK-DVDLDVLNHPI 275
XP_009419586 265 SIFVAVLSFIAAVGFILYGGRLFCMLRQFPIESKGRQKKLHEVGSVTAICFTCFLVRCCVVGLSAFDT-DMSLDVLNHPI 343
ERN19596     168 SLFIAAISFFAALGFLLYGGRLFLMLRRFPIESKGRRKKLHEVGSVTVICFICFLIRCFVDAWSAFDS-HLSLDVMDHPI 246
EER97820     182 KIFIVAVSFIALLGFSVYGGRLFVLLRRFPIESKGRQKKLYEVGTVTAICVTCFLIRCVVVALSAFDA-DVSLEVLDHPI 260
Q9FEG2       176 KIFIAVVSFIAALGFLLYGGRLFFMLRRFPIESKGRRKKLHEVGSVTAICFTCFLIRCVVVAVSAFDK-DLTLDVLDHPV 254 thale cress
EDP05347     265 LNIAYYGLAEILPSAAVLYILRKLPPKRQNAQGYQ 299
Q6EU03       246 LNFIYYLIVEILPSSLVLFILRRIPSKLRLAQYHP 280 Japanese rice
XP_001778362 256 LNAIYYTLVEIVPSALVLYILRKLPPKRLSGQYHP 290
EFJ23006     248 LDTVVYLLVEILPSALVLYILRKLPPNRpgppgye 282
XP_002979144 260 LNFLYFLLVEILPSALVLYILRKLPAKRATSTAYK 294
XP_011626514 276 LNLIYYTLVEIVPSALVLFILRKLPPKRVSDQYHP 310
XP_009419586 344 LDLIYYTLTEILPSVLVLYILRKLPPRRVSGQYHP 378
ERN19596     247 LNLIYYLLAEIVPSALVLYILRKLPPKRISGQYHP 281
EER97820     261 LDFFYYMFAEILPSALVLFVLRKLPPKRVSAQYHP 295
Q9FEG2       255 LNLIYYMVVEVLPSALVLFILRKLPPKRVSAQYHP 289 thale cress
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