5D0N


Conserved Protein Domain Family
Kinase-PPPase

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pfam03618: Kinase-PPPase 
Kinase/pyrophosphorylase
This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.
Statistics
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PSSM-Id: 460990
Aligned: 299 rows
Threshold Bit Score: 261.925
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam03618 is a member of the superfamily cl00780.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5D0N_A          127 IYIVSDGTGWTAEHSVNAALGQFencladrgcaVNTHLFSLIDDMDRLIEVIKQA-AKEGALVLYTLADPSMAEAT-KKA 204
B9KHZ9            9 LHLVSDSTCETVIAVARSAVEHFks------leVNEFVWSLVGSKRQVDKVMLNInPERHNLIMYTVVDDDLRKYL-KEK 81  Anaplasma ma...
Q2GJC2            9 LHLVSDSTCETVVSVARAAVEHFks------leVNEFVWSLVGSKSHVDRIISSIdRKRNNLIMYTVLDDDLREYL-KKK 81  Anaplasma ph...
Q6MNY2           10 IYILSDSTGETAATMIRAALVQYtt------kdVNIIRCKNVRTDTQAEAVIEEC-FERRGMLAYTVASQGLRAKI-REM 81  Bdellovibrio...
WP_014245306     10 IIIISDGTGETATAISRAIMTQFpd------reVYFTRFKNVRTTEQVDAIFTEA-AIHHDLIIYTIVTSELRDYI-GDV 81  Halobacterio...
jgi:Hipma_0510    8 IYLISDGTGETATKIAKAFLVQFky------pnIIKRKFIEVREKEKIDEIVEKA-KDERPLVVLTIADKDLRDYAnERF 80 
BAI80025         18 IFIISDGTGQSAINLMRACLIQFee------qhVRLTVFSKVNTKEQIESILNQA-REQKAFVAFTLVKKELRRYM-HKL 89 
jgi:Calni_1778   17 VYILSDGTGQSAINVVRACLIQFdn------inAKLIVYSKMDDEEKIKLALSRA-KEDKAFVAFTIATKSLRRLI-HTI 88 
jgi:Flexsi_0343   6 VYILSDGTGQSAINIVKACLIQFed------peIKLSVYSKVDNEDKIVNILEKA-GRNRAFVAFTIAKKSLRRLV-HEV 77 
WP_013011569      5 IYIISDGTGQSAMSIMRAALLQFdk------pdAKFTVYSMVDREEQLVSILNHA-KMDYSFIAYTMVSKGFRDIV-RRF 76  Denitrovibri...
5D0N_A          205 CDFWGVPCTDVLRPTVEAIASHIGVAPSGIPrsspSR-NGRLSEDYFQRIDAIDFTIKQDDGALPQNLYRADIVLAGVSR 283
B9KHZ9           82 ATAQSVRCIPVLAHVIREISCYLQVT--KDP----NAhPHKLGDEYFNRIDAINYTISHDDGQNLWDIDQADIIIVGVSR 155 Anaplasma ma...
Q2GJC2           82 AEAYNIRCIPILSHIIREISCYLSVA--KDP----NAhPHRLSDEYFNRIEAINYTIAHDDGQSLWDIDGADIIIVGVSR 155 Anaplasma ph...
Q6MNY2           82 ASGKGIPYFDLLGPLLSTLDTFFGQHSEDTV----GA-LRAVDERYFKRIEAIEYTVKHDDGKTFAELDKADIVLVGISR 156 Bdellovibrio...
WP_014245306     82 ARNRHVRALDLIGHALTAFSNYFEQEPKSEP----GL-LHAVNDDYFKRVAAMEFTLNHDDGRNLETLSLADVVLIGISR 156 Halobacterio...
jgi:Hipma_0510   81 NQ-IGVIILDLFGYYINKFEEFFGQKARNVS----GL-LHRISDRYFEKIKAIEYTVEHDDNRSSRNLDQADIILVGLSR 154
BAI80025         90 CHDYEIIHHDILGPPVEKLSNFLGAKPLENP----NL-LRRVDDKYFKRIEAIEFTINHDDGKNLKGLKEADIVILGLSR 164
jgi:Calni_1778   89 CHEDNIMHHDILGPPVEKFKIFLDSEPREFP----NL-LRRLDSKYFKRIEAIDFAIEHDDGKSMKRIREADIVILGLSR 163
jgi:Flexsi_0343  78 CHKREIIHHDILGPPVEKLSAFLDSEPIENP----NL-LRKVDSKYFKRIEAIEFSINHDDGKNLKNLEEADIIILGLSR 152
WP_013011569     77 CAENGLKSIDLLGPPLDSLESYMGKPQLEKP----GL-LRKVDEKYFKRIEAMEFTLTHDDGKLMRGMNEADLIILGLSR 151 Denitrovibri...
5D0N_A          284 TGKTPLSIYLAQ-KGYKVANVPIVMGVDLPKSLFEINQDKVFGLTINPAILQAIRKTRAKTLGFDGrQ-SNYAEMDHVRQ 361
B9KHZ9          156 TSKSPTSIYLAY-RGYRVVNIPLVCSVQLPVDPATIADKLVVGLTIDADRLIQIRRNRLISMKhqe--ncNYVSYEQVVE 232 Anaplasma ma...
Q2GJC2          156 TSKSPTSIYLAY-RGYKVVNIPFVHSITLPIDSAALADKLVVGLTIDIDRLIQIRRNRLISMKnqs--ncNYISYEQVEQ 232 Anaplasma ph...
Q6MNY2          157 TSKTPLSIFLSH-KGWKVANVPLVLDTPLPEELFKIDQRRIVGLIIDMDSLQRIRKSRLEKFGQDP-G-GSYASMSHIAK 233 Bdellovibrio...
WP_014245306    157 TGKTPLSVYLSQ-HGVKVVNVPLIKGTEIPESLFQIDQRKIFALTINPDALLEIRRKRLTTLGASN-HtGDYAEQSKVIE 234 Halobacterio...
jgi:Hipma_0510  155 TSKTPLSIYLAQeGGYKVANFAIVKGEKLPDSLFEVDQNKIVGLTIDPMRLYEIRKQRAKKLGLAN-S--SYASLSRIYE 231
BAI80025        165 VSKTPTSFFLAQ-LGYKVVNIPIVPEIPLPKELFEIDQKKIVCLVMDPEVLQKVRMERMKHYKTTS----NYTDLKRIFE 239
jgi:Calni_1778  164 TSKTPTSFYLAQ-LGYKVVNIPLIYGMKIPEEVYSIDQNKIVCLVMDPETLQKIRQERLRHYKTNS----DYTNIKKILE 238
jgi:Flexsi_0343 153 TSKTPTSFFLAQ-QGYKVVNIPVIPEVGIPEEVYKADQNKIVCLMMEPDILQKIRIERLKHYRTMS----KYTNINNILE 227
WP_013011569    152 TSKTPTSFFLAQ-QGFKVVNIPLVPEIPIPEEVFKVEQHKVVLLVMDPEVLQKVRSARLRHYKTTS----NYNNLPKIFA 226 Denitrovibri...
5D0N_A          362 ELVHANQIFAQNpSWPVIAVTGKAIEETAAVIL 394
B9KHZ9          233 EINEMKKICAKN-RWPTIDVTQKSVEEIAATII 264 Anaplasma marginale str. Florida
Q2GJC2          233 EISEVNRICMKN-QWPLIDVTQKSIEETAATII 264 Anaplasma phagocytophilum str. HZ
Q6MNY2          234 EIEYAEKIFKVNrRWPVFNVTERALEETASEIV 266 Bdellovibrio bacteriovorus HD100
WP_014245306    235 ELEWANDLFSENkRWPIFNVTDKAIEETASEIL 267 Halobacteriovorax marinus
jgi:Hipma_0510  232 EVEYANSIFKKHpQWLIVDVTNRSVEETASEIV 264
BAI80025        240 ELEFVYDLVKKNrQWHIVDTTNKSVEETAREII 272
jgi:Calni_1778  239 EVEFIYELVSKNrRWHLVDTTNKSVEETAREII 271
jgi:Flexsi_0343 228 EVEFMYALKDKHrEWHIVDTTNKSVEETAREVL 260
WP_013011569    227 EVEFCYELIRKNrKWSMIDTTNKSIEETAREII 259 Denitrovibrio acetiphilus
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