3JB9


Conserved Protein Domain Family
Cwf_Cwc_15

?
pfam04889: Cwf_Cwc_15 
Cwf15/Cwc15 cell cycle control protein
This family represents Cwf15/Cwc15 (from Schizosaccharomyces pombe and Saccharomyces cerevisiae respectively) and their homologs. The function of these proteins is unknown, but they form part of the spliceosome and are thus thought to be involved in mRNA splicing.
Statistics
?
PSSM-Id: 428176
Aligned: 94 rows
Threshold Bit Score: 110.425
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3JB9_h         1 MTTAHRPQFDPARGH------SEMAPTriTSSRALPAHLKLKYRQESQGTEEEV---RKQDLRE----ALLRAEAAHFAT 67  Schizosaccharom...
XP_003456897   1 MTTAARPTFEPARGGrgkgegDLSALSkqYSSRDLPGHTKIKYRQPTQDAPEEV---RARDFRR----ELEERERVAARE 73 
XP_018645219   1 MTTAGRPTWDTAKGSrgkwegDLSALSkqYSVRDLPAHTKLKLRQEGQGRPEDI---QGKDFKR----ALEEKEKRLAQE 73 
XP_001743599   1 MTTAHRPTWTPAQGGtgkydsSLGAMSkqYSVRDVVAHTKLKVREEGQGTRFEN---SLKDFRS----ELEDREREHHEK 73 
XP_004993599   1 MTTAHRPTWTPAQGGkgkydsSLGLISqqTSVRDAPAHTKLKFRHDVETK-------DEEEMKR----ELEQREAKHFDD 69 
A0BCU2         1 MTTAHRPTYRPAIGGseqggnKMLVHSrsYHSKDLPAYLILKMRKPGQGTQEEL---EQKDFKM----DLLKREEEGKRQ 73  Paramecium tetr...
EDL43073       1 MTTAHRPTWYNAIGGenqggnRKVSQTakVCSRDLPGHTKMKTRDLSDYV-------EDKEVIRnnliQLE----GEAAE 69 
Q8IBM8         1 MTTAHRPTWYNAIGGdnqggnRKVSQTlkVCSRDLPGHLKMKTRDLSDYV-------EDKNMIKnnliQLENKNNKETSK 73  Plasmodium falc...
XP_001386912   1 MTTNHRPTLESKRGK------VNSITDtiSHSRALPQQTTLKYREDGSKVEHKKgkrALEELKT----ELLIREGRLPEL 70 
Q230Z1         1 MTTAHKPTWQPARGTetg-gaSLSVPTrsYSSRDLPGHLTLKVRQDGQNSRNDL---KYKDFKA----ELLEKEKKYQKE 72  Tetrahymena the...
3JB9_h        68 QEhGASSEEVSQns----------------------kLIEGFTSPSTddKPNNDVEvdyqeLLRQ--------------- 110 Schizosaccharom...
XP_003456897  74 KTrERGPRE-------------------------------HTTSSSSssSSSKRPRl---dQIPAa-------------- 105
XP_018645219  74 KSgRPSINATSQqpaits-------------akrpssAAVAPTIDSStiGSIKRTRpetttTVSTt-------------- 126
XP_001743599  74 QLkEQQKIEG----------------------------LAAITEGRTglPAEKRPRi---tHIEAn-------------- 108
XP_004993599  70 IRkEEEKRA-------------------------------GITAITGaaDEAKTSRpskllAITTd-------------- 104
A0BCU2        74 RElKALGVSETSlai--------------------eaTQKNQNKDVQepQILKKTKveekeIYPQ--------------- 118 Paramecium tetr...
EDL43073      70 KDnSHRLLAIENikkltnhdytnpfpededdeveeewKSRRRKGGGKakRKGKSKK------------------------ 125
Q8IBM8        74 ---GNKLLAIENikkltnhdfk------npfpededdIIGDEWKKKShkKNKKKKKl---kMKNKrnvkkrkvkhdmsed 141 Plasmodium falc...
XP_001386912  71 ---------------------------------------------SEndHISKRIKl---kENHEnlqiket-eegnndi 101
Q230Z1        73 KNeKLGIYSQIE-------------------------EDKKDPITYKepEQRKKLKtessnVIQQlkqygsddeddiknk 127 Tetrahymena the...
3JB9_h       111 TL----EADEDASdsddsvdssnkn---------------sevsikrrkteSNSqesvdssNSESSDEESd-----sEDE 166 Schizosaccharom...
XP_003456897 106 NL----DADDPLTd----------------------------------------------dDEDEDSDQDs-----dDDD 130
XP_018645219 127 NL----DADDPWDedydedqddviitkk--------snhnksknstedrfdDDQndgdddeDADNDDVDDd-----dEED 189
XP_001743599 109 AL----DADDDDDdad-------------------------------------------daDSDSDESDSd-----dDDD 136
XP_004993599 105 EA----DEDLPEDdes-------------------------------------------adESDSDSDSDd-----dDDD 132
A0BCU2       119 ------DADDKEFikssddee----------------------envqkpekPTVqqqelkiEEDSSSSSSd-----eEDD 165 Paramecium tetr...
EDL43073     126 ------DSEEGSQeegcrpggi---------------------sdgssddqSDNsagdsagHSSDDASDDssanqseDEE 178
Q8IBM8       142 EM----SHDMNDYnssdnnssd---------------------nnssdnnsSDNnssdynsSDNNSSDDDe-----sDEE 191 Plasmodium falc...
XP_001386912 102 GI----DDDNEDKidnksded----------------------gdvsndneGDDidsysgsEDSESDDEGd-----sEDE 150
Q230Z1       128 PIsgigDNDEESDsnsssseeideeaikkkaaesinpfpqdaddldfantsSSEsekedkeASSQSSSSDs-----dSDD 202 Tetrahymena the...
3JB9_h       167 TQQLLRELENIKQERKREQMLQEEKNRALEQEKREREIAFGNELLNkas-----------sgSFQVKRRWDEDVVFRNTH 235 Schizosaccharom...
XP_003456897 131 TAALLAELEKIKKERAEEQERKEREQKAEEERIRMENILSGNPLINlagqqq----qnqtqnTFRVKRRWDDDVVFKNCA 206
XP_018645219 190 EEMLLAELAKIKRERAEEAARLAAERKAAEETIRMENILKGNPLLNssn-----------ssEFKVKRRWDDDVVFKNCA 258
XP_001743599 137 TELLLAELEKIKRERADEQARKDTERIAADEEQRRESALQGNPLLRgq------------asDFTVKRRWDDDVVFKNCA 204
XP_004993599 133 TAQLLAELEKIKKERAAEQARKEELKAEEESRVRLASIVKGNPLLNdgq-----------sgDFTVKRRWDEDTVFKNCA 201
A0BCU2       166 DELLMREYQKIKEQREIEEKKKILEKQEYLEKNREEEIIKGNPLLVs--------------eDYSLKKKWYEDTIFKNQS 231 Paramecium tetr...
EDL43073     179 EKELLRELENLKREKMEKERQEKLA--QERLQSKKNNVLTNNPLINlednnsdneegegegeGASRKRKWTEEAIFRNTC 256
Q8IBM8       192 EKELLRELENLKRERMEKLKKEKEE--QELLKKKKNNVLTNNPLINledss-------dndeVSTKKRKWTDDAIFRNTC 262 Plasmodium falc...
XP_001386912 151 TELLLAELAKIRQERQEEKERVEEQ-------AKIDRALSSNPLVSvksed------kdkieEAPKKKSWRSTTTFSNRP 217
Q230Z1       203 EELLMKEYQKIKEQREAEEKEKLRLKQEELEKQRQQNLLTHNPLLDqs-------------sGYNLKKKWFEDSVFKNQA 269 Tetrahymena the...
3JB9_h       236 KGVDDTPRp--GFVNDMLRSEFHKKFLARFV 264 Schizosaccharomyces pombe 972h-
XP_003456897 207 KGVDEARKe-kRFVNDTLRSEFHKKFMEKYV 236
XP_018645219 259 RGEVDHVKr--GFVNDTLRSEFHKKFMKKYI 287
XP_001743599 205 KVEERGKKe--TFVNDTLRSEYHRKFMDKFI 233
XP_004993599 202 RGEKQSKKp--RYINDTLRSESHMKFMERYI 230
A0BCU2       232 RLEVKEKQ---RFINDAVRSDFHRKFLNRYI 259 Paramecium tetraurelia
EDL43073     257 EK---KEKr-sTFINDTVRTAFHKKFLFKYI 283
Q8IBM8       263 EK---KEKktpSYINDTVRSAFHKKFLFKYI 290 Plasmodium falciparum 3D7
XP_001386912 218 NKVSEQD----TYTNDTLRSKHHQNFLNKFV 244
Q230Z1       270 KKDKDEKQ---RFINDNVRSDFHRKFLKKFI 297 Tetrahymena thermophila SB210
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap