2Q2E,2ZBK


Conserved Protein Domain Family
Spo11

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COG1697: Spo11 
DNA topoisomerase VI, subunit A [Replication, recombination and repair]
Statistics
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PSSM-Id: 441303
Aligned: 62 rows
Threshold Bit Score: 358.776
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2Q2E_A        15 LAREKLLEIAEKIYNQF-EEEVvpSVSLPSRTKANLEYSDESDVWVYGDRESERSAKTVKGAFQLLKTTYATDFlINEHL 93 
AFU59897      10 EVIKKIKTIMKDVSTDLmVQKMmpVLNVPKVGYDNTVWSDEKRMLTIGDKTVGISPDSTKKIPTFTQYLVMANA-VRKLL 88 
WP_012310095   7 DVKSKVLEIAREVAKAI-KEGRfpELEYPPNTQRNIVFDERMGYIFRPTFYGKIKGSHSKSLRTLSGVLYGMSR-ALDHL 84 
WP_012634087  10 KTVQKIEKLAETVLRSV-KGGKnpFLEIPVRSLANVQFNPRKRLIELKDQKQRRYFFNVSMAKKFMQTFLVSDA-CKELI 87 
WP_012909908  26 KTLDSLRKLASDVAKSA-TQKTapEMSILSRSLSNVKFNQSQKILEMGSSKTSRELFNLSQAKAFMQTVLVGSG-CKRLI 103
WP_012037336   7 EIVNRLKGLGDSIISDI-DAGKnpSLDIRMRALNNVYFDEQSGIIKLGNDQQKRFYFNLGQAKKFLQTLLIAKQ-IKILL 84 
WP_013248616  11 AVGKKLVGMADVVITAA-QRAKdpTFEIPIRALSNVSFNPRRGLIEMGEKKQSRSFFNVGMAKKFMQTMLVADA-LAELQ 88 
WP_050726289  10 KTLAKIEALAKGVVQEV-KKRKnpRLVVPLRTLSNVQFNAKKKIIELGADKQERAFFNVAQAKKFMQTFLVASA-CKELL 87 
WP_088820156  10 ITEDVLREFGNMLIRDI-FSDKnpSFQTSVRSRTNVVFDKSKGFLTLGDSKEEHSFINVSQSKGFMQTIAIAAK-CYSFI 87 
WP_095415984  27 RTLERIQALADHVIQAA-KARKdpYIDIPARTLSNVYFNKKKRFIEMGKAKNRRHLFNLAQAKSYMQTMLVASG-CKRLI 104
2Q2E_A        94 ARNR-GSTLRELYYISEGw------Dy-AKFKEQGESDRLIEDLEILTSLQREYFHMRPEEDGaTMFGPIEITEQtkrGE 165
AFU59897      89 DEEM-ESTIRGMYYATLStvgdeknKq-KFWTGQEDSDDAIKAIELLTGVPREEFSVTSKPKG-MISGPITLRVG---GD 162
WP_012310095  85 ENGL-TMTKRDFYYLHKVer----lKgtLFPEDQRETDARIILMELILGMPREAFSITSDPRG-WIYGDIELIDRs--GR 156
WP_012634087  88 DAGK-TTSIRDLYYMTKHalg--etRq-NTFEEQEESDPIIEDLEVAIDALREELHLFASGRG-SMVGPLSIRDA---GD 159
WP_012909908 104 EQGK-TTSLRGLYYMLKHtid--gtSe-ETFEEQSESDTMIEDVEVLLSSLREELHLYAQKRG-EMVGQITVVDS---GD 175
WP_012037336  85 EQDKpALSIRQLFYTLKHdip--gaGe-NTFDVQDESDPLIEDVELMVDALREELNLIATPNG-VLAGPMIVEDKt--GD 158
WP_013248616  89 QADL-TTSLREIYYRTKHtiq--dsHe-NTFDTQDESDPIIEDLEVSLIALREELHVRAENSG-SIVGPVVFGDD---GD 160
WP_050726289  88 EVGK-TTSIRDLYYMTKHtlg--dtRq-NTFDEQDESDPIIEDLEVTVDALREELHLFANRKG-LMVGPMTVIDS---GD 159
WP_088820156  88 KQNQ-HATIRDLFYQLKYslg-ddlDe-NIFNEQSESNPLIEDLEVALDLRREQLNLNANRKG-VLVGNMRIIDKf--GD 161
WP_095415984 105 EQGK-TTSIRGLFYLLKHtie--gtKe-ETFATQEECDPIIEDVEVTLNALREELHVYATNRG-AMVGEITIVDS---GD 176
2Q2E_A       166 ---RnIHCQ-KdVGEGGYQIPFNV--ENIEFQKHDASMIIAIETGGMYARLMENGFDEAYNAILVHLKGQPARSTRRIIK 239
AFU59897     163 ---V-IDCNlG-SRATSQLIPTNI--RDVEIVKVKADFVMVVEKDTVLNNIRKSGFIQKYNAILMTGSGEPDRATRMMVK 235
WP_012310095 157 ---V-LKAD-Q-VGEMGYSVPPRP--ENIKFKRIGVKAVVAVEKVGPAKNMIELGIPEEKKIAIAILQGQASRSMRRFLR 228
WP_012634087 160 ---A-IDLR-R-MGSGGWSVPSIVeeHVVQFGKSEAKYVLLIEKDAVWKRFNEDKFWAREKCIIVTGLGQPPRGVRRIVQ 233
WP_012909908 176 ---E-IDCT-R-MGSGGYGIPSIVepDRITFKNVKAKFILHVEKDTVWQRFNEDKFWLKHNCILTHGAGQPPRGVRRMLY 249
WP_012037336 159 ---V-LDFT-K-MGSAGGAVPPIVedDFFHIKEMNADYILVVEKYAVWNLLNQEKFWKKNNCILLTGKGQPARAERRLLA 232
WP_013248616 161 ---R-VDCA-K-LGKGGYSVPSIVepEYLEIRRCTADFLLLVEKGTQWNRLSEDKFWRRYNCVLLTGNGQPPRGVRRLAR 234
WP_050726289 160 ---T-IDLR-R-QGSGGWGVPSIVepNVIRFGKTEAKYVLLVEKEAVWSRFNEDKYWKKEQCMLIHGGGQPPRGVRRLVQ 233
WP_088820156 162 etvE-IDGA-K-TGRSGWAIPSDVd-NDIQFVDIDADYVLVVEKDALWYRLNEDKFWKKENAIIISPMGQAARGTRRLIR 237
WP_095415984 177 ---E-IDCT-R-MGSGGYAIPSIVepNVIQFVKCDAKFVLHVEKDTVWRRFNEDKFWKKHKCILTHGMGQPPRGVRRLLH 250
2Q2E_A       240 RMNEELGIPVAVFTDGDPWSYRIYASVAYGAIKSAHLSEFMATPAAKFLGLQPSDIVE-----YELSTD---KLTEQDVS 311
AFU59897     236 ALNEEWKKPVVVFADADPWGLGIALRYKIGSESLSYDSDRLVTPDAKVLGMMFSDIYE-----YNIPEVarlAASDDDLN 310
WP_012310095 229 MLSDE-GVPLAVLTDLSPWSLRIAATVIYNSINSAHIPH-LATPEARFIGILTRDVEEgffkdYKFALE---PLTQADYK 303
WP_012634087 234 RLHSELGLPVYVLVDNDPWGFYIYSVLKQGSINLAYESMRMAVPKARFIGLSSFDKAK-----FKLPGNvsiRMNDQDDA 308
WP_012909908 250 RLHNELKLPVYCLLDNDPWGYYIYSVIKQGSINLAYESERMAIPGARYLGLRSLDYDR-----CGLSSSvkiKLNDQDIK 324
WP_012037336 233 RFGEEYDIPVYVFTDMDPWGYYIYSVYKYGSINLAFFSEKAACPRAKYLGLSVKDVMN-----FDMPRSswiKLNDEDHK 307
WP_013248616 235 RLHEEHKLPVYVLVDNDPWGYYIYSVVKQGSINLAFESQRMAIPKAKFIGLSSADPER-----YELPRNvgiKLNEKDIT 309
WP_050726289 234 RMHSELKLPVYVLVDNDPWGFYIYSVIKQGSINLAYESMRMAVPGARFVGISSFDPER-----YRLPDEtaiRMDDGDHK 308
WP_088820156 238 KLSDK-GLPIYVFNDCDAWGWYIYWTIKTGSINLAYISDDLATPKAKFIGVTMSDLEA-----YPFLKGltmKANDMDIK 311
WP_095415984 251 RLHYELGLPIYCLLDNDPWGYYIYSVIKQGSINLAYESQRMAIPEARFLGLRSFDFER-----CGLSESvtiALTEADRK 325
2Q2E_A       312 ALRSELSDPRF-ESDYWKEQIQLQLDIGKKAEQQAFAGKGLD-----FVTEVYLPNRLKEMG 367
AFU59897     311 RANDMKKKPWF-QDKQWQKELDLFLKKKEKCELDAFFKHGFK-----YLAEVYLPRKLREAG 366
WP_012310095 304 AALDNKSLPNL-QNEFWQKENDWFLQNKKKAELEIFKAMSPSaktlkEYFIRYLSEKLEQHL 364
WP_012634087 309 RAKQMLAYPWF-KDPKWQREIQEMVRSGEKYELEALSRRGIS-----FVTEEYLPRKLRDRD 364
WP_012909908 325 RAKQIASYPWFiKKKAWQKEIEMMLKNGFKLEVESLISKDIS-----YVTEEYVPELLESGE 381
WP_012037336 308 RIAEISEYPWF-KKDYWQKELTDLKKFGYKIEQDALVSKSIE-----FTANNYLPTKIENKD 363
WP_013248616 310 RAKELLNYQWF-QKPAWQQEIKRMLTSGLKYELDALANKDFQ-----YLTKKYLPRKLKEKD 365
WP_050726289 309 RIKQMLEYPWF-EKKQWRRELEAMASNNKKYEIEALSRRGIS-----FITEEYLPKKLRDRD 364
WP_088820156 312 KAQEMLNYPWIsRYPEWVNELNLVLKMKKKLEQNSLEGPKLS-----FV-DEYINDKIKKGN 367
WP_095415984 326 RAKQIMEYPWFkHKKAWQDEIKKLLDNGFKLEVEALISKDIS-----YVTEVYAPQRLRDGD 382
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