1X8Z


Conserved Protein Domain Family
PMEI

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smart00856: PMEI 
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Plant invertase/pectin methylesterase inhibitor
This domain inhibits pectin methylesterases (PMEs) and invertases through formation of a non-covalent 1:1 complex. It has been implicated in the regulation of fruit development, carbohydrate metabolism and cell wall extension. It may also be involved in inhibiting microbial pathogen PMEs. It has been observed that it is often expressed as a large inactive preprotein. It is also found at the N-termini of PMEs predicted from DNA sequences, suggesting that both PMEs and their inhibitors are expressed as a single polyprotein and subsequently processed. It has two disulphide bridges and is mainly alpha-helical.
Statistics
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PSSM-Id: 214860
Aligned: 112 rows
Threshold Bit Score: 65.0835
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1X8Z_A      2 AMDSSEMSTICDKTLNPSFCLKFLNT--K-----FA---SPNLQALAKTTLDSTQARATQTLKKLQSIIDG--G---V-D 65  thale cress
NP_190324  78 gSVSGDMTWWCNKTPHAETCNYYFRKssQnninlRP---PRFRSEFLRMLVKVALDQAVITHSQTVKFGPS--C---T-N 148 thale cress
AAF19577   71 psqsqspslACKSTPYPKLCRTILNAvkS-----SP---S-DPYRYGKFTIKQCLKQASRLSKVITSYARR--V---E-S 135 thale cress
NP_173733  28 shlnahfiTSCKQTPYPSVCDHHMSNspL-----KTlddQTDGFTFHDLVVSSTMDQAVQLHRLVSSLKQHh-S---L-H 97  thale cress
NP_196116  78 qpsplppNIACKSTPYPKLCRTILSAvkS-----SP---S-DPYHYGKFTMKQCLKQARRLSKVINRFAQR--V---EaD 143 thale cress
NP_567227  25 llPSNSSSTICKTTPDPKFCKSVf---pQ-----TS---QGDVREYGRFSLRKSLTQSRKFTRTIDRYLKR--NnalL-S 90  thale cress
NP_181833  28 iQTNSAVSISSNSNSH----FSRFSRhrS-----SP---SSKTKQGFLATVQESMNHALLARSLAFNLTLShrT---V-Q 91  thale cress
BAF00855   22 SQTLSNSSTICKTTPDPKYCKSVFPH---------S---QGNVQQYGCFSIRKSLSQSRKFIRTVDRYIKR--NahlS-Q 86  thale cress
NP_191460  28 lqtsvfahssnskftkisrhpnsdSSsrT-----KP---STSSNKGFLSSVQLSLDHALFARSLAFNLTLShrT---S-Q 95  thale cress
NP_566103  29 igNATSPSNICRFAPDPSYCRSVLPNqpG------------DIYSYGRLSLRRSLSRARRFISMIDAELDR--K---G-K 90  thale cress
1X8Z_A     66 P-----R------SKL---AYRSCVDEYESAIGNL------------EEAFEH---------LASGDG------M-G--- 100 thale cress
NP_190324 149 N-----Q------RKA---AWSDCVNLFQNTVAQL------------NRTLKG---------LNPAAS------S-D--- 183 thale cress
AAF19577  136 K-----PgsataeEIG---AVADCGELSELSVNYL------------ETVTTE---------LKTAQVmtaalvE-H--- 182 thale cress
NP_173733  98 K-----H------ATS---ALFDCLELYEDTIDQL------------NHSRRS---------YGQYSS------PhD--- 133 thale cress
NP_196116 144 PgtstvE------EVS---AVADCGELAELSVEYL------------ETVTEE---------LKAAEL------M-Taal 186 thale cress
NP_567227  91 Q-----S------AVG---ALQDCRYLASLTTDYL------------ITSFETvnittssktLSFSKA------D-E--- 134 thale cress
NP_181833  92 T-----H------TFD---PIHDCLELLDDTLDML------------SRIHAD------------NDE------E-D--- 123 thale cress
BAF00855   87 P-----A------VIR---ALQDCRFLAGLTMDYLltsfetvndtsaKTSFKP---------LSFPKA------D-D--- 133 thale cress
NP_191460  96 T-----L------MLD---PVNDCLELLDDTLDML------------YRIVV----------IKRKDHv----nD-D--- 131 thale cress
NP_566103  91 V-----A------AKStvgALEDCKFLASLTMDYLlss------sqtADSTKT---------LSLSRA------E-D--- 134 thale cress
1X8Z_A    101 ---M-------NMKVSAALDGADTCLDDVKR-----L---RS-VDSSVV--N--NSK--TIKNLCGIALVI 146 thale cress
NP_190324 184 ---VkctdfdaQTWLSTAQTNIETCRSGSED-----Ln-----VSDFVM--PviSNK--NLSDLIGNCLAV 237 thale cress
AAF19577  183 ---V-------NSLLSGVVTNQQTCLDGLVE-----A---KSgFAAAIG--S--PMG--NLTRLYSISLGL 229 thale cress
NP_173733 134 ---R-------QTSLSAAIANQDTCRNGFRDf---kL---TSsYSKYFP--V--QFHr-NLTKSISNSLav 183 thale cress
NP_196116 187 vdrV-------TSLLGGVVTNQQTCLDGLVD-----A---KSgFATAIG--T--PLG--NLTRLYSVSLGL 236 thale cress
NP_567227 135 ---I-------QTLLSAALTNEQTCLDGINT-----AassSWtIRNGVA--L--PLI--NDTKLFSVSLAL 184 thale cress
NP_181833 124 ---V-------HTWLSAALTNQDTCEQSLQE-----K---SEsYKHGLA--M--DFVarNLTGLLTSSLDL 172 thale cress
BAF00855  134 ---I-------QTLLSAALTNEQTCLEGLTTaasysA---TWtVRTGVA--L--PLV--NDTKLLGVSLAL 185 thale cress
NP_191460 132 ---V-------HTWLSAALTNQETCKQSLSE-----K---SSfNKEGIAidS--FAR--NLTGLLTNSLDM 180 thale cress
NP_566103 135 ---V-------HTFLSAAITNEQTCLEGLKS-----T---ASe--NGLS--G--DLF--NDTKLYGVSLAL 179 thale cress
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