6CNB,4A3C,3H0G,3AYH


Conserved Protein Domain Family
RNA_pol_Rpb4

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pfam03874: RNA_pol_Rpb4 
RNA polymerase Rpb4
This family includes the Rpb4 protein. This family also includes C17 (aka CGRP-RCP) is an essential subunit of RNA polymerase III. C17 forms a subcomplex with C25 which is likely to be the counterpart of subcomplex Rpb4/7 in Pol II.
Statistics
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PSSM-Id: 461080
Aligned: 48 rows
Threshold Bit Score: 50.2657
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6CNB_D        10 FLSDYEVLKFLT-DLEKKhLWDQKSlaalkks---rskgkqNRPYNHPELQGITRNVVN-YLSI----------NKNFIN 74  Saccharomyces c...
Q8IM54         9 FITKFETFLVIKkELEYSrNIDKHLynkylinkddnfkeiyEKYFMKLISDKILYKSIHkYIMDtcphvipkniYHKNDN 88  Plasmodium falc...
Q7RDJ1         9 YITKFEAFVVIKkELEYSkNIDKYLcskliikaddpfkdiyEKNFIKLVSDKILYKNLQkYIIDtnphliskelYNKDYQ 88  Plasmodium yoel...
Q18G98        12 YQTVSEVKLLLQ-NIEAErAA-----------------------EADRDLRYELARAIE-HVNR----------FADLD- 55  Haloquadratum w...
Q9HQG9        12 PLTVSEAKALLS-EVETErAL-----------------------DEDRELRFELSRAIE-HANR----------FALLE- 55  Halobacterium s...
Q5V586        12 FLTVAETKEILE-DLEMErAA-----------------------DEDREMRYELKRAIE-HVNR----------FALLD- 55  Haloarcula mari...
WP_011323550  12 YLTTPEAKELLA-DIEAErAL-----------------------DEDREMRYELARAIE-HVNR----------FALLD- 55  Natronomonas ph...
Q2NE43        11 PITISEAKEILMkKVEEKvDEN--------------------NEIDGHQFTYEQNLTID-YVNK----------FALLD- 58  Methanosphaera ...
Q8U216        11 YITIAEAKELLLkRREEEvKA-----------------------GIEEPLYYEARLALE-HAER----------FAKLP- 55  Pyrococcus furi...
Q54S04        31 FLLNSEVAILLEhRKGISeSEGTEFpqnt--------llihLYYNSINDIIRTFHKTLA-YAEK----------FSRYKN 91  Dictyostelium d...
6CNB_D        75 QEDegeeressgakdaeksgiskmsdesFAELMTKLNSFK---L-FKAEKLQIVNQLPANMVHLYSIVEECDA------- 143 Saccharomyces c...
Q8IM54        89 ESKdii-------------------qdiSNKIVQFFKNIDiydF-DKKEKIQMIDIHCVNIVDLYVIMNYADK------- 141 Plasmodium falc...
Q7RDJ1        89 EIKhli-------------------ddtFNKIVNFFKNISiynI-DKKEKIQMIDIKCINFIDLYVIMDYDDKkyaqifl 148 Plasmodium yoel...
Q18G98        56 PSD-------------------------SRELVDELLTEEk--V-DEPTAIKIADLLPQDRDELRAVFAQERY------- 100 Haloquadratum w...
Q9HQG9        56 PAE-------------------------SREFVDELLALDv--LdDEAVAYKIVDLLPRTRTELRSVFANERY------- 101 Halobacterium s...
Q5V586        56 PEE-------------------------SLQLVEELEELEk--V-DTPTAYKIANLRPLDRDELRAVFAQERY------- 100 Haloarcula mari...
WP_011323550  56 VEE-------------------------AQALVEDLRELEk--V-DEATAYKVANLLPEDRDELRTVFAQERY------- 100 Natronomonas ph...
Q2NE43        59 ADD-------------------------AKELRTKLEEY----L-TPVQAVKVVDLMPEDLDDLRLIFAKERG------- 101 Methanosphaera ...
Q8U216        56 ADK-------------------------AKEAVEELMNAFe--WmSDRIACKIVDIMPEDSMDLRVIFAKEEY------- 101 Pyrococcus furi...
Q54S04        92 KTS-------------------------IKQVRTALSKQN---L-EEFEIASLANLCPEISDEAKSLIPSLK-------- 134 Dictyostelium d...
6CNB_D       144 -----------------------------RFDEKTIEEMLEIISGYA 161 Saccharomyces cerevisiae S288C
Q8IM54       142 -----------------------------KCEEYKIEQILNMLKDVH 159 Plasmodium falciparum 3D7
Q7RDJ1       149 fhiqkiitfislcnclrngthiliiffsfRCEESKIEHILNLLKDVH 195 Plasmodium yoelii yoelii
Q18G98       101 -----------------------------ALNGDELDAILNTVKKYA 118 Haloquadratum walsbyi DSM 16790
Q9HQG9       102 -----------------------------AMSGDELDEILDVVAKYV 119 Halobacterium salinarum
Q5V586       101 -----------------------------TLDGDELDEIINIVKQYA 118 Haloarcula marismortui
WP_011323550 101 -----------------------------SLSGDELDDILDIVAKYA 118 Natronomonas pharaonis
Q2NE43       102 -----------------------------TFETDALKNILDLLDQYR 119 Methanosphaera stadtmanae DSM 3091
Q8U216       102 -----------------------------QPTQEEMKQILDILDKYR 119 Pyrococcus furiosus
Q54S04       135 -----------------------------KMEDDELQAILDELSNLR 152 Dictyostelium discoideum
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