Conserved Protein Domain Family
COG7

?
pfam10191: COG7 
Golgi complex component 7 (COG7)
COG7 is a component of the conserved oligomeric Golgi complex which is required for normal Golgi morphology and localization. Mutation in COG7 causes a congenital disorder of glycosylation.
Statistics
?
PSSM-Id: 431125
Aligned: 4 rows
Threshold Bit Score: 1000.96
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q3T1G7         2 DFSKFLADDFDVKDWINAAFRAGPKDGAAGKADG--HAATLVMKLQLFIQEVNHAVEETSLQALQNMPKVLRDVEALKQE 79  Norway rat
Q7QA49         1 DVSAFSGDDFDVSSWINASYERSQKTATGSVGKEa-FVSSLVSKMQLYVQQINVALEQTGGQVLKNIPKVISDANMLQIE 79  Anopheles gambi...
XP_002020468   2 DVSALSEATFSPADWINANYKKYIEENGSKDGDAtsFIQSYVAKLQLYVQQVNYAVEESSRQVVSSMPRIAKESTTLHSD 81 
Q9FGN0         4 DLGPFSDEKFDAKRWVNSSCQARHPQDSLEKH-----LVDLEMKLQIASEEIGASLEEQSGGALLRVPRATRDVLRLRDD 78  thale cress
Q3T1G7        80 ASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETFKTQDIAVISAKLTGMQS 159 Norway rat
Q7QA49        80 SGLLKQRMNQVQREIAHLQTETGDCMVSLERLDDIKQRLQSSKQCLQEADGWGKLAGELDDLLEKSDIDASSGKLLSLQK 159 Anopheles gambi...
XP_002020468  82 VSQLQEKMSAMRQEVAAVQNETGECMATLERLNTLQTKLQAAKESLQESDGWGNLLAELEDGFERNDLKGVCEKLIALQK 161
Q9FGN0        79 AVSLRGSVAGILQKLKKAEGSSADCIAALARVDNVKQRMEAAYKTLQDAAGLTQLSSTVEDVFASGDLPRAAETLASMRN 158 thale cress
Q3T1G7       160 SLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAAFTSQSVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLATWQEL 239 Norway rat
Q7QA49       160 SLAAQVGLHGHSERENLVEYFKNRLEALVSPSVVVALRSMDTAACRRYVGIFEGIGRLAQLKQYYRTVLKTFVQEQWSSA 239 Anopheles gambi...
XP_002020468 162 SLHAQEQLPGHAERLTQVEDFKNRLEALASPSVVQCFAESNLEQAQHYVQIFASIQRLPQLQQYYRAVQKNLWQQQWKQT 241
Q9FGN0       159 CLSAVGEVAEFANVRKQLEVLEDRLEAMVQPRLTDALTYHKVDVAQDLRVILIRIGRFKSLELQYSKVRLKPIKQLWEDF 238 thale cress
Q3T1G7       240 CQRDl---------------------------PLDRQLTGLYHALLGAWHTQTQWATQVFKNpYE-VVTVLLIQTLGALV 291 Norway rat
Q7QA49       240 IEGSe--------------------------sGGSDVLKEFYDHLVELLKSHLRWSCQCFGE-AT-DCVLAVADALENLD 291 Anopheles gambi...
XP_002020468 242 LELQgtet---------------------qpqQQQQFLTLYYDQLLEHCQRQVKWCSNLFSEeST-QPFLVIAELLPALQ 299
Q9FGN0       239 DTKQranklanersesqrlssgdefqstssqtSFASWLTSFYDELLLYLEQEWKWCMVAFPDdYMtLVPKLLVETMGVLG 318 thale cress
Q3T1G7       292 PSLPMCLSEAVERAGPEl------------------------eLTRLLEFYDTTAHFAKGLEMALLPHLQD----HNLVK 343 Norway rat
Q7QA49       292 PTRESVVRSALKRATDK--------------------------FWTLTQFSKVNVSMGSLIEGWVRGGPQQdircDDETT 345 Anopheles gambi...
XP_002020468 300 PTRDAHILQLLKTSNER--------------------------LELLGLFSQVNHSFVLHLNSLLEQSHITl--sDELHR 351
Q9FGN0       319 ASFVSRLNLATGDAVPEtkalakgvmdllsgdlpkginiqtkhLEALIELHNVTGSFARNIQHLFAE--------SELRI 390 thale cress
Q3T1G7       344 VVELVDAVYGPYKPYQLKYGDLEESNLLIQISAVPLEHG----------EVIDCVQELSQSVHKLFGLASAAVDRCAKFT 413 Norway rat
Q7QA49       346 IDRLANSLFVFFGIFLKEYPTLENSQLEASLQGLTIVGT----------APADSVHNLESANAKIIRWALEAVTRCQDIT 415 Anopheles gambi...
XP_002020468 352 Q--LGEAVFEYFHKFIQQYPRLEETQLSTQVDRLLSNQS----------TPSDAVRHLEESTRKLYEWLKEACERCSAIT 419
Q9FGN0       391 LIDTLKAVYSPFESFKQKYGKMERAILSSEIAVVDLRGAvtrgvgaqgiELSETVRRMEESIPQVVVLLEAAVERCIGFT 470 thale cress
Q3T1G7       414 NGLGTCGLLTALKSLFTKYVSHFTNALQSIRKKCKLDDippns-------------------lfqeDWTAFQNSVRIIAT 474 Norway rat
Q7QA49       416 QNCALLSLGSVLQNYLLTYLDQYNKVQKQLAASQPSQT----------------------------DWNLLQLSVVLLQY 467 Anopheles gambi...
XP_002020468 420 SDLALCKLITLLNGIFKRQLENFGRIQRQLGLSLGSSSyaa----------------------qseNWSLLQYTMSQLQC 477
Q9FGN0       471 GGSEADELILALDDIMLQYISMLQETLKSLRVVCGVDGtgdgvgskkdasaekressrkmdltsneEWSIVQGALQILTV 550 thale cress
Q3T1G7       475 CGELLRQCGDFEQQLANRILSTAGKYlsdsysprslagfqdsiltdKKSPAKNPWqEYNYLQKDNPAEYANLMEILYTLK 554 Norway rat
Q7QA49       468 LGSFRQAAYELEQTFLQQVLTKHSQL--------------------TAGSARARF-EYRLNTKGEFNELHKLATTFQQPS 526 Anopheles gambi...
XP_002020468 478 LADFQVQLHQFEHDLHARMATLAAKL--------------------TKQSSRGNItIFQTCDHAARTQLLNAIADYQQKK 537
Q9FGN0       551 ADCLTSRSSVFEASLRATLARLNSSLsislfgtnldhnlshlkseqTAGDLSMAGrASMDVAAIRLVDVPEKAHKLLNLL 630 thale cress
Q3T1G7       555 EKG-SSNhnLLSVSRTALTRLNQQAHQLAFDSVFLRIKQQLLLV-SRMDSWNTAGIGETLTDDLPAFSLTPLEYISNIGQ 632 Norway rat
Q7QA49       527 SES-GRE--YFSEFHQRMKRTCEDIHDTMLQIAFSPITKHFKQIePAATGPTGAAGGTTAMDTLPDYSYAPQEYITLISQ 603 Anopheles gambi...
XP_002020468 538 AEA-TESlgIFPQIYAALKLQFSETHDITLNILLQPIETHLAHIrPAAETHPSTGI------DMPSFSFAPQESITQIGQ 610
Q9FGN0       631 EQSkDPRfhALPLASQRVAAFADTVNELVYDVLISKVRQRLGEV-SRLPIWSS--VEEQTAFPLPNFSSYPQSYVTSVGE 707 thale cress
Q3T1G7       633 YIMSLPLNLEPFVTQEDSALELALHAGKLPFPPEQgeelpeldNMADNWLGSIARATMQTYCDGILQIPAVTPHSTKQLA 712 Norway rat
Q7QA49       604 YLLTLPQHLEPLLLSPAAALKAVLEVADHRYASNR--------PCADVFLALVVEESEALYVEQIENICSLSVSGAKQLA 675 Anopheles gambi...
XP_002020468 611 YLLTLPQHLEPLLLAPSALLKQALEVCNVKYTQAI--------PCADVLLSLVVEQCCILYQAQILQIKTLPASAAKQLS 682
Q9FGN0       708 YLLTLPQQLEPLAEGI---------------STNGdsnnedaqFFATEWMFKVAEGATALYMDQLRGIQYISDRGAQQLS 772 thale cress
Q3T1G7       713 TDIDYLINVMDALGLQPSRTLQNIATLLKAKPEEYRQVSK-----GLPRRLAATVATMRG 767 Norway rat
Q7QA49       676 TDIEYFGSVLEEMGQSLGGNLQQTVKLLRAPLESYASAAT-----GCDPELVAAIRQKRN 730 Anopheles gambiae str. PEST
XP_002020468 683 VDIEYLSNVLEELGLSINLQLSQILTLLKAAPDQYLTLSS-----GCEPRLVTAIRQMRN 737
Q9FGN0       773 VDIEYLSNVLSALSMPIPPVLATFQTCLATPRGELKDVMKseagnELDCPTANLVCKMRR 832 thale cress
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap