Conserved Protein Domain Family
DLC-like_TCTEX1D1
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cd21458: DLC-like_TCTEX1D1 
dynein light chain (DLC)-like domain found in Tctex1 domain-containing protein 1 (TCTEX1D1) and similar proteins
Tctex1 domain-containing protein 1 (TCTEX1D1) is a genetic modifier of disease progression in Duchenne muscular dystrophy (DMD). It can interact with ZMYND10 that stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms. The model corresponds to the (dynein light chain) DLC-like domain of TCTEX1D1.
Links
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Statistics
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PSSM-Id: 412006
Aligned: 20 rows
Threshold Bit Score: 173.246
Created: 28-Jan-2020
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8N7M0        76 FPVVTVNHILKDVVTSYLQVEEYepELCRQMTKTISEVIKAQVKDLmIPRYKLIVIVHIGQlnrQSILIGSRCLWDPKSD 155 human
XP_002114011  70 FPSAAIKSIVQDVLESYLQNESYdsEVCREMTKTVSEVIRSRVKDLnLRRYKLVSLVYIGQltnQGVKLGSRCLWDPSND 149 Trichoplax adha...
XP_784517     74 FPVTTVKSMLKETMEGYLQDKRYepEWCKKMTKTISDDLKAQVKDLmLPRYKIIVLVHIGQlqdQGLKVSSRCLWDSSND 153 purple sea urchin
XP_002131536  83 FPVSSITKIMQEVMGDYLQNKPYepEFCRKMTKVISDEVKLKVKELhVPRYKVVCIVHIGQlnnQGLRISSQCLWNDKYD 162 vase tunicate
XP_025008942  98 FPVAAVDAILKAVLEGCLRERRYepGLCREMAATVGEVIKARVKDLvLPRYKIVVVTHIGQlsgQGMQISSRCLWDPATD 177 chicken
RUS71938      75 FPYASVRNIIKESMENLLSEEQYrpEFCRDMTKTLSETIKARVKSLmIPRYKIICLVQIGElkaQGMRVGSRCLWDEAHD 154 eastern emerald...
PIK33666      74 FPVTAVKSILKDVVVRHLDNRQYepEFCKETTKVISEDVKSRVKLMkLGRYKIICLVHIGQlkdQGLHVTSRCLWDADSD 153 Japanese sea cu...
XP_001637504  74 FPEGNIRNIMKEVLIENLADVNYdpNTCRQLTKTISETLKNRVKELsVQRYKIICLVHIGQlgkQAMRIGSRCLWDANFD 153 starlet sea ane...
XP_017275740 124 FPVSDATAILREALSSFLKEERYevQRARELSLTLSAVIRERVKALrTPRYKLVVLVTVGQlngQGLEIGSRCLWDVTHD 203 mangrove rivulus
XP_028413480  78 FPANKIKEVVEGILGRELKDIPYeaENCRQLTSRISDIIKREVKDLdLDRYKLVCIVHIGQrgnQEIKVGSRCLWDVRLD 157 Dendronephthya ...

Q8N7M0       156 TFSSYVFRNsSLFALANVYAVYLE 179 human
XP_002114011 150 NFSSHSYQNaSLFAVATVYGIYLE 173 Trichoplax adhaerens
XP_784517    154 TSASYEFRNsSLFAAAMVYGVYYE 177 purple sea urchin
XP_002131536 163 TFAACEYTNsGIFAAACVYGVYFE 186 vase tunicate
XP_025008942 178 TFSSYVFKNtSLFALAVVYAVYFE 201 chicken
RUS71938     155 TFSSHEFRNkSIYAVASVYGVYYE 178 eastern emerald elysia
PIK33666     154 NSSSFEYRNsTLFAVATVFGIYHE 177 Japanese sea cucumber
XP_001637504 154 TYTTYEFKNgSLFGVATVYGVYFE 177 starlet sea anemone
XP_017275740 204 TFASYSFKNsSLFGVASVFAVYFE 227 mangrove rivulus
XP_028413480 158 TFISAEYKNtSLFAIATVFGIYFE 181 Dendronephthya gigantea
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