Conserved Protein Domain Family
Prothymosin

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pfam03247: Prothymosin 
Prothymosin/parathymosin family
Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.
Statistics
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PSSM-Id: 460859
Aligned: 13 rows
Threshold Bit Score: 29.489
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q28G57          2 ADTDVDTTTaeVPVTKDLKEK-K-EvVEEPEKAEng--kgDAPSNGT---EENGADHGAQNDdaeEEDEEgdvegEGEGE 74   tropical claw...
XP_005997417    2 SETKVDHPS--ETPAKDLKEK-K-E-VEGSGNGK------EVPANGNaenEENGEQEVENEV---DEEEEeeageEDEED 67  
3_pfamImport    1 -----------QLFNLDLKEK-K-EvVEEAENGR------DAPANGNaenEENGEQEADNEVaflD-KKAeegtvVDLVL 60  
XP_014319175    2 SDTAVDTSS--EITTKDLKEK-K-EvVEETENGR------DAPANGNa-nEENGEQEADNEV----DEEEeeggeEEEEE 66  
Q5BL59          2 SDTAVDASV--EKTPKDLKAKeK-EvVEEAENGK------DKPTNGNaenEENGEQE--------NEGDEeeevdEEDEE 64   tropical claw...
A5PLC8          2 ADAKVDSAT--EISAKDLKE--K-KlIEEKENGK------DA-TNGKe-nEENGEPEID--------DEDddevdEDDE- 59   zebrafish
Q54B17        411 KDKKEKLASfiKLSFYNLKKK-K-ElLKKSKKLK------NNNNNNNeddLLNSQQVPDDNMefeQQQQQ-----QKEEE 477  Dictyostelium...
XP_006642006    2 ADTAVDTTTttEVTPKDLKEK-K-EvAEEVEKTEkengsgDAPANGT---EANGADHGEETPedeEEEDE-----EAEGE 71  
XP_005155974    2 ADTAVDTTTtsEITAKDLKEK-K-EvVEEAAEAAkengseDAPANGNg--TTNGASHEEEEAhedEEGGE-----DEEA- 71  
P08814          2 SEKSVEAAA--ELSAKDLKEK-K-EkVEEKAGRK-------ERKKEVveeEENGAEEEEEET-------------AEDGE 57   cattle
XP_006006539    2 SDAAADTTE--EVSTKDLKEK-----ISGKEKSEp----gAETTDVNgeeEENGAEADEETPeklNDED------EGDEE 64  
XP_023063724    2 SDAAVDTSS--EITTKDLKE--KkEvVEEADNGR------DAPANGDa-nEENGEQEADNEvdeeeeeggeeeeeeeegd 70   Ugandan red C...
XP_015216401    2 ADTKVDTSS--EIPTKDLKEK-K-ElVEDAENGK------DTPANGNaenEENGEQEAENEV---EDDDEdevgeEDDEE 68   spotted gar
Q28G57         75 GEEEEDEEEgegDENETDGLSVKRPAED----EEK----TETKKQKTENG 116  tropical clawed frog
XP_005997417   68 DEGEGEEED---DDEEAEGATGKRAAED----EEDd--eVETKKQKKDED 108 
3_pfamImport   61 NCSPGEEEDg-dEDEEAEAATGKRAAED----DEDd--dVDTKKQKTDED 103 
XP_014319175   67 EEGDGEEEDg-dEDEEAEAATGKRAAED----DEDd--dVDTKKQKTDED 109 
Q5BL59         65 DEVEGDDDD---EDDEVEGATGKRAAED----DEDddddVETKKQKTDED 107  tropical clawed frog
A5PLC8         60 -EGEGDEDEdedDDDEDLGGGTKRGADDdedeDEDdeddVDPKKQKVn-- 106  zebrafish
Q54B17        478 EKKEKEEEDgeeEEEEEEIT------------EKQifedIKLNKEQFFDL 515  Dictyostelium discoideum AX4
XP_006642006   72 GEEDEEGEEgaeEE--ADGHPVKRPAEE----EEK----VETKKQKTENG 111 
XP_005155974   72 -GEAEEEENgaeEEAAAEEHPVKRPAEE----EEA----VETKKQKTEEN 112 
P08814         58 EEDDGDEEDeeeEEEEDEGPALVRAAEE----EDE----ADPKRQKTENG 99   cattle
XP_006006539   65 DEEEVDDEEeedEEDEEEGQAVKRRADD----DDN----TGKKKQKT--- 103 
XP_023063724   71 geeedgdedeeaesatgkraaeddedddvdtkkqktdedd---------- 110  Ugandan red Colobus
XP_015216401   69 DDGEGEDDE---DDEEAEGGAGKRAAED----DDEd--dVETKKQKTDed 109  spotted gar
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