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FERM_B-lobe: FERM domain B-lobe
The FERM domain has a cloverleaf tripart structure (FERM_N, FERM_M, FERM_C/N, alpha-, and C-lobe/A-l...
View in Cn3D
PKc_like: Protein Kinases, catalytic domain
The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-speci...
SH2: Src homology 2 (SH2) domain
In general, SH2 domains are involved in signal transduction; they bind pTyr-containing polypeptide l...
FERM_F1: FERM F1 ubiquitin-like domain
This is an F1 lobe domain consisting of a ubiquitin like fold found in FERM region of Jak-family tyr...
Jak1_Phl: Jak1 pleckstrin homology-like domain
This entry is for the pleckstrin homology-like (PHL) subdomain found in Jak1 proteins. JAK1 is a mem...
FERM_F2: FERM F2 acyl-CoA binding protein-like domain
This is an F2 lobe domain consisting of an acyl-CoA binding protein fold found in FERM region of Jak...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
PTKc_Tyk2_rpt2: Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Tyrosine kinase 2
PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in prot...
SH2_Jak_Tyk2: Src homology 2 (SH2) domain in Tyrosine Kinase 2 (Tyk2), a member of the Janus kinases (JAK)
Tyk2 is a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein fam...
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