Conserved Protein Domain Family
Corazonin

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pfam17308: Corazonin 
Pro-corazonin
This domain family is found in Corazonin proteins in Drosophila and other Anthropods. Corazonin (Crz)is a neuropeptide with a wide spectrum of biological functions in diverse insect groups. It was first discovered due to its myostimulatory activities on the heart muscle of Periplaneta Americana and the hyper-neural muscle of Carausius morosus. In Drosophila melanogaster, Crz plays diverse roles ranging from a regulator of insulin producing cells in the brain to roles specific to tissues, life stages, and gender.
Statistics
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PSSM-Id: 375119
Aligned: 9 rows
Threshold Bit Score: 151.159
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q299B0               21 QTFQYSRGWTNGKRAL---TPPSLLSHGHFNRASDLGFSDLYDVQDWSSERRLERCLAQLQRSLLSRVygSVVDFNANRP 97  Drosophi...
XP_001955601         21 QTFQYSRGWTNGKRALh--PVSPLITNGYFHRINELGFSDLDDMPDGKSDRWLQICLSKLQKSLINRN--PGEGLSLKRV 96 
WGS:AAPP:GF16166-PA  21 QTFQYSRGWTNGKRALn--TGSPLLGNGHLHRSNELSFSDLYDLQDWSSDRRLERCLTQLQRSLLSRNcvPGVELNLNRM 98 
EDW42199             20 QTFQYSRGWTNGKRSFn--AASPLLANGHLHRGSELGLTDLYDLKDWSSDRRLERCLSQLQLSLIARNcvPGSDFNTNLV 97 
KNC25893             21 QTFQYSRGWTNGKRAG-----AATTLNNLLHNKEDDGMSELFEVQEA-NERRLERCLSQLQRFVRNPLllHTTAALALNP 94 
WGS:AAQB:GK11346-PA  23 QTFQYSRGWTNGKRSSlssTPTLLNNGQHFHRSNDVSFADFYDFPATISERRLERCLTQLQHFVGNSLlhRSFATGLDTD 102
WGS:AAPU:GI10817-PA  21 QTFQYSRGWTNGKRAT----PSALLNTGHNLGLLDA-----FEMQEKPSDIKLERCLMQLQHLAGNALlhHSFANGLAYN 91 
Q5W1L3               21 QTFQYSRGWTNGKRAP----PAALVTNGHNLGLLDI-----YDIQDRPTDIKLERCLLQLQHFVGNALlhRSFANGLAYS 91  Drosophi...
XP_001993872         21 QTFQYSRGWTNGKRAP----PAALLSNGHNLGLLDL-----YDIQDKPTDLKLERCLMQLQHFVGNAMlhRSFANALAYN 91 
Q299B0               98 EPDSSDSGSSRNRANN-------NNENVLYPTPIQNRHHSSNELLEEIsaavagsGPTGAGSGEPSVFGKH 161 Drosophila pseudo...
XP_001955601         97 DTDSGDINLKSRLNNN-------NIDHVLYSISNPNRNQQTNDIFEEF-------KTTGRILPETNVYGKQ 153
WGS:AAPP:GF16166-PA  99 DTDSGDTNLHSRPNNN--------ENENLVYSNPKQNRRQSNELLEELs------VAAVGGSSEPNVFGKH 155
EDW42199             98 DPDPENSVHPRLSNIN-------GENVLYSSANIPNRHRQSNELLEEL-------SAAGGASAEPNVFGKH 154
KNC25893             95 AAPSSSQSSNSNNNMN---------------NIPYGRNHQSNELFEEL--------GAAGTIIDTNDYAKH 142
WGS:AAQB:GK11346-PA 103 SSDAQSSSNENSPYTN------------------PKRHHQSSELFEDLnaa--vgSVPAAGPGEPNDFIKH 153
WGS:AAPU:GI10817-PA  92 GNRPDPTDLNIHARPRp-----sANNNDNNLLYPRDNQHQSNELYETV-----------ADPVEPVDFGKH 146
Q5W1L3               92 ASRPDPETDVRSINIHsrp--gsGNNNIENSLYPNVNHRQSNELFEAL-------NAPGPDAVEPNDYGKH 153 Drosophila virilis
XP_001993872         92 ANRPETEAETRGLNLHplhpsanNNNNNENSLFPNSNNHQSNEIFEALa-----aSAPGVDSVEPNDYGKH 157
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