6TED


Conserved Protein Domain Family
Leo1

?
pfam04004: Leo1 
Leo1-like protein
Members of this family are part of the Paf1/RNA polymerase II complex. The Paf1 complex probably functions during the elongation phase of transcription. The Leo1 subunit of the yeast Paf1-complex binds RNA and contributes to complex recruitment. The subunit acts by co-ordinating co-transcriptional chromain modifications and helping recruitment of mRNA 3prime-end processing factors.
Statistics
?
PSSM-Id: 461126
Aligned: 123 rows
Threshold Bit Score: 121.142
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6TED_U       375 FVKLPNFLSVEPRPFDPQYYEDefed-eemlD----------EEGRTRLKLKVENTIRWRIRRDeegN--EIKESNARIV 441
CCE41020      94 LLKTPMHLNIDPHPFDPITFKEevetnelerVekglt-skqiYNEKLAEKLINETTVRWRYHNSg--NdeIVKQSNAHFV 170
XP_007377999  84 MLKMPVFLNVEAHPFDPNEFKArikenaelrQktdlt-ekqkHNDLVSEKLTNENTIRWRYSNL---NdeIIKQSNAHFI 159
CCE79538     101 VMKMPVFLNVDAHPFDANEFKEtvkqnavdrSnryld-ekqmQNDLVAEKLLNENTIRWRYSNRg--DdeIIKQSNAHFV 177
Q6BIB4        81 TLKMPVFLNVEAHPFDPTEFKEkvgqnaierKnssmn-akqvQNDLNAEKLLNENTIRWRYTNSg--NdeIIKQSNAHFV 157 Debaryomyces ha...
XP_001386594  51 SLKMPVFLNVEAHPFDPTEFKErvqqtaaerStrtsltdkqkQNELVAEKLLNENTLRWRYSNSg--NdeIIKQSNSHFV 128
XP_002615064  51 IIKVPVFLQVDAHPFDPNEFKAkvaenarerHasamd-akamENDVIAEKLLNQNTLRWRYTNAg--NdeIVKQSNAHFV 127
XP_006689520  79 HLKMPLFVNVDAHPFDPVDFKEnielnarnrDinikd-sklkKNDLIREKLTNENTIRWKYSNE---NdeIIKQSNCHFV 154
XP_001483576  77 LLKMPVFLNVDAHPFDPSEFKQkvqqnfeqrKksdms-lkqiHNDLVAEKLLNDNTVRWRYSNRg--DdeIIKQSNAHFI 153
XP_013934883  83 VFSLPRYLFVDPEPFAPTTFESnineflkdsLkdst--skelQDSLEFKKLEVQNTIRWRYAKTa--SdeLYKQSNASIV 158
6TED_U       442 KWSDGSMSLHLGNEVFDVYKAPLqgDHNHLFIRqgTG--LQGQAVFKTKLTFRPHSTDSATHRKMTLSLADR-CSKTqKI 518
CCE41020     171 QWDDGTISLKIGNEMFDVKTLPV--ADNYLVKSykTAeiLQTDSIVENTINLLPASS-DSIHKRLTQVMKNI-HFKD--K 244
XP_007377999 160 QWDDGSLSLKIGQELFDLKELPI--FDNYLVRShdSLeiLQNDSIITKTINLLPASTSTSTHRKLTQAVKNI-QKKA--K 234
CCE79538     178 QWDDGSLSLKIGNELFDFKELPL--YDNLLVKShdDHeiLQVDSTIKSQVNLIPSSTFTDTHRKLTQAVKNI-QRKD--K 252
Q6BIB4       158 QWNDGSISLKIGSEMFDYKELPV--YDNFLVKThdDYeiLQNDSIINKLVNLLPSSAFTSTHKKLTEAVKNI-QKKD--K 232 Debaryomyces ha...
XP_001386594 129 QWNDGSLSLKIGNELFDVRELPL--TDNFLVKThdSYeiLQHTSILNKTINLLPSSTLTSTHRKLTQAVKSI-QTKD--K 203
XP_002615064 128 QWDDGSLSLKVGSELFDFRALPL--ADNFLARShvDHevLQNDSILTKTASVLPASTGTATHRQLTQAVKNI-QKKD--K 202
XP_006689520 155 EWDDGSLSLKIGNEMFDFKSLPL--YDNILVRShdDLeiLQASTILTKTSNLLPTSTGTSTHKQLANAIKFL-QQKD--K 229
XP_001483576 154 QWDDGSLSLKIGNELFDYKTLPI--TDNFLVRAhdDLeiLQNDAILTKLVNLLPTSTTASTHRKLTQAVKNI-QRKD--T 228
XP_013934883 159 EWEDGSMSLKIGDEFFNIKLNNN--EDEILVAEsgDLylPVT--ELKKSIQVLPSSTSSRAHKILANTLQSNlRLKKsKK 234
6TED_U       519 RILPMAGRDPECQRTEMI 536
CCE41020     245 ILNTTTEDDPLKKQRiad 262
XP_007377999 235 ILGTITDDDPLKKQRlad 252
CCE79538     253 ILNTVTDTDPMLIQriad 270
Q6BIB4       233 ILNTITDNDPLLKQRMAd 250 Debaryomyces hansenii
XP_001386594 204 ILNTITNDDPMMKQRLad 221
XP_002615064 203 ILNTLTDADPMSKQRAAd 220
XP_006689520 230 ILNTITDSDPLEVQRNAd 247
XP_001483576 229 ILNTITENDPMMKQRLad 246
XP_013934883 235 INTIVTTEDPELKAREME 252
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap