6JZA,1TBQ,1Z7K


Conserved Protein Domain Family
Kazal_2

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pfam07648: Kazal_2 
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Kazal-type serine protease inhibitor domain
Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains often occur in tandem arrays. Small alpha+beta fold containing three disulphides.
Statistics
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PSSM-Id: 400135
Aligned: 40 rows
Threshold Bit Score: 36.7019
Created: 4-Apr-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6JZA_A   34 LCIEQCK-PHKRp---VCGSNG---KTYLNH-CELHRDACLTGSKIQ-----------VDYDGHC 79   house mouse
Q95011  114 DCNHNCTnTEFDp---VCDTNG---SVYRNL-CVFQMRRCELQLESQri-------qlAEDRKFC 164  Caenorhabditis elegans
P26461   43 SHLFFCT-REMDp---ICGTNG---KSYANP-CIFCSEKLGRNEKFD-----------FGHWGHC 88   pig
Q95011  306 STCITCPkDEKKi--pICDNRN---MTHPTL-CSFIQYNCEARNNEDee-------rvLVHIKSC 357  Caenorhabditis elegans
Q9VUD9  293 KCNFQCPkASLS----ICASNGkcvVNFPGQ-CELSQWNCFNTKNVFh----------QVHDAEC 342  fruit fly
Q9VUD8  255 NCDELCTkFEYSp---ICAHNGiciHEFANQ-CVMNTFNCKHRDLSFrav-----dedVCRLGVC 310  fruit fly
P70663  443 QDPETCPpAKILd--qACGTDN---QTYASS-CHLFATKCRLEGTKKghq------lqLDYFGAC 495  house mouse
P36233   98 QDPTSCPaPVGEfe-kVCSNDN---KTFDSS-CHFFATKCTLEGTKKghk------lhLDYIGPC 151  rabbit
P13671  788 SPEEDCShHSED----LCVFDTdsnDYFTSPaCKFLAEKCLNNQQLH-----------FLHIGSC 837  human
P34714   75 ECISKCPeLDGDpmdkVCANNN---QTFTSL-CDLYRERCLCKRKSKecskafnakvhLEYLGEC 135  Caenorhabditis elegans
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