7A6H


Conserved Protein Domain Family
RPC5

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pfam04801: RPC5 
RPC5 protein
This family represents the RPC5 protein which is part of the RNA polymerase III complex.
Statistics
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PSSM-Id: 461434
Aligned: 48 rows
Threshold Bit Score: 245.302
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7A6H_M         5 E--DDPVVQEIDVYLAKS-LAE--KLYLFQYPVRPASMTYd-dIPHLS--------------------AKIKPKQQKVEL 58 
EFO19660      14 D--IDDIVAEIDVILSRNpGSS--ELYRIQYPIRKV-NPFg-cGVVK---------------------ARYKKNVKVLEM 66 
Q23206        31 DsvEDQVVWECDVVVCNStPNT--EMFSVSYPSSKR-DAWd-aKRFPI--------------------ARYKKNVRLLEM 86  Caenorhabditis ...
EGT47843      30 GssEDQVLWERKIVVCNSiPNT--EMFCVSYPPSKR-DAWd-gKRLPT--------------------ARYKKNVRLLEM 85 
EFP04449      31 DgtEDQVLWEKNVVVCTSaPNT--EMFCVSYPSSKR-DAWd-gKRFPM--------------------ARYKKNVRFLEM 86 
XP_002642969  28 EeeEDQVVWERNVAVCTSvPNT--EMFCVSYPSSKR-DAWd-aKKFPV--------------------ARYKKNVRLLEM 83 
EDQ86070      45 D--DDPVIAELNVFVSTA-LQE--QLYLYQYPMRSALRPFvsgDGNLE--------------------SRFRPKAQAVEL 99 
Q4QG17        11 E--DDEVVASFNVYASPA-LVN--QAHIFQYPLRRRQRPYe-aTEIKLfstsgtvaeeseallaqgkgSSVLQPGSRLTM 84  Leishmania major
Q4CYE9        14 D--DDEVIATYNVYASP--LQQ--QLHIFQFPLRRKTQPYe-tDEVRLfvtegvthvgkeatppsassASILSPSSRLTM 86  Trypanosoma cruzi
XP_001415474  14 D--DNPVVETIPVYF-NRpPDDggEMVLIQYPLRPPDRPYd-vANVES--------------------VRYKPDAAKLEM 69 
7A6H_M        59 EMAIDTLN----PNYCRSKGEQIAlnvdgacadetstyss-----------klmdkqtfcssqttsNTSRYAAALYRQGE 123
EFO19660      67 RLPVDKLS----SSFDKGRAEHLAlisgtnagasaadnfr-----------imdeevyvgrsfgndAPVHYAVGFFKNQC 131
Q23206        87 RFMTDTQL----GSYDKKKAELMYmdgdvpkkghgidal------------randeiyegrafihdHPIVNAIGFFKNGE 150 Caenorhabditis ...
EGT47843      86 RFMTDTTN----GSYDKKKAESMYadggspqkgngagipp-----------rsneeqyegrafvhdHPIANAIGFLKNDE 150
EFP04449      87 RFLTDTST----GSYDKKKAELMLyeggeskkagasaapgie-------alrandevyegrafvhdHPIVNAIGFMKNGE 155
XP_002642969  84 RFLADTSV----GSYDKKKAELMYsggadsgkgghksgvea---------irandevyegrafihdHPIVNAVGFMKNGE 150
EDQ86070     100 KVPIEPDNn---PHYDFPKGEELAdlanepypqaksdpegsndegntktfpsglmdhllmtstctpQASPYAAALIHRGE 176
Q4QG17        85 KCSLDTFGspsfRPLPEFAPDMLGqmelqrhhtf----------------------nytlqsqpflPQSNYVLGYITLEG 142 Leishmania major
Q4CYE9        87 HCRLDTFGs---SSFVEPSHQQQRqlpmqqtedrfcrgeq----------qrrnsyhyalqshpfqPRCDYAVGFIVDGA 153 Trypanosoma cruzi
XP_001415474  70 TMPIEESE----RNRDEDAAEHTRisslllts---------------------------ssakaeaHGDGVVVGTIHNGA 118
7A6H_M       124 LHLTPLHGILQLRPSFSYLDkADAKHRer-----eaANEAGDssqde---aeddvKQITVRFSRpeseqaRQRRVQSYEF 195
EFO19660     132 LYICPLTGTFDMKRSISYLNgQGKNRTartseddmsDSEEEGssk--------npSPIRVRFKRpeterqKKRREQSSAH 203
Q23206       151 FFIHPLTGAFEMHRSIQGLNk--KKKSdgksgksdeDSSGEEedvk------pssAAVRVKFSRpeterqKKRREASALH 222 Caenorhabditis ...
EGT47843     151 FFVHPLAGSFEMRKSIRALNk--KRKggksg-nsddDSTGDEegresn--qkptsSAVRVKFSRpeterqKKRREASALH 225
EFP04449     156 FFIHPLTGSFEMHRSIRALNr--KKKlgkgg-nsedESTEDDeevdpr--kaatsGAVRVKFSRpeterqKKRREASALH 230
XP_002642969 151 FFLHPLTGSFEMHRSIHALNk--KKKsgkg--gsdeDSSEEEdepdpk--kagtsSAIRVKFSRpeterqKKRREASALH 224
EDQ86070     177 VHVAPLRNVFQLRPNLHHLDeAEARQK---------AAKAAGneeeaadgpaesdsRVRVKVKRvetaraAAARKKSYAH 247
Q4QG17       143 IHLTPVSTIQQFTPALSIPEsSTGAVRvteafcsqsNSTAMPg------------FAAADRIQR------ELRRQRSRVL 204 Leishmania major
Q4CYE9       154 IHLTPVSTIQQFTPIVKPTT-LIAAHRvgdeftsvqSTPIVPg------------LAISDRINR------EMLRQRSVML 214 Trypanosoma cruzi
XP_001415474 119 MYLTPIEAVYQMRPSLQHLDaADSARQ---------PHDAAReerelqeeeermlLPLQVQVRRretakqTEMRVQSHAF 189
7A6H_M       196 LQKKHAEepwvhlhyYG-----LRDSRSEHERQYLLCPGSSGV--ENTELVKSPSEYLMMLM-PPSQEEEKDKPVAPSn- 266
EFO19660     204 RSRLIEQdpwtplnin--------------------cmadtgsikYNESLLSVPVTMLNSCTvPDPVQLVQEAIIGEKmd 263
Q23206       223 REKKIASdmwipmkvHLkdgdpVAEKIDGIsqng-------llldDPEASRMSIRALVNRAIiCGVKEELVIESGKEHm- 294 Caenorhabditis ...
EGT47843     226 REKKIANdlwipmnvYLneddhVTAKVQQIsgkef------erqiPMIEPSMSIRDLVNKAIiCGVKEELVIESGKEHm- 298
EFP04449     231 REKQIASdlwipmkvHLkedepVNVKKAIIstgstvkgeesgvteVGPPPEMNIRELVNRAIiCGMKEELVIESGKEHm- 309
XP_002642969 225 REKKIASdlwipmkvHLkddesVGRKKEMIssnsvkt--egggaeTLPPPDMSIKELVNRAIiCGLKEELVIEAGKEHm- 301
EDQ86070     248 MRQQIDEetwvp------lqyrHSSTRVAMEQRELLRSTAAMP----IPLEMTPEEYVNRLNaQASDSRQQTTRKTPSik 317
Q4QG17       205 NGEADTA--------QEiqffrDDSVESSAMRSRLCSSTLERI--TGNLNAASEPAEVENSLfPPEILQSGGISGGDEah 274 Leishmania major
Q4CYE9       215 NTDAATA--------KElqyfpIGSVESMAMRRRLCSTTYDVSslAQTVGNQRSNTQTEDSLfPPELLISGGISGGEDaa 286 Trypanosoma cruzi
XP_001415474 190 LRQREHEeawi-------plqpSMPGDADTEFVKAYVTTTHGE---SCGQAVTAREYLDVMC-----PVSGSKRVAPEde 254
7A6H_M       267 ---------vLSMAQLRTLPLAD-QIKILMK--NVKVMPFANLMSLLGP-----------------SIDSv----aVLRG 313
EFO19660     264 aldlndckqlISLRRIRHLPEVQ-QVRALMI--KARCISTNEAQQYVSKcip---------------------rhlLISR 319
Q23206       295 ----------LSKQRIDDLPDPNlQLKAHMV--KSHVMKTSEMRRLIDP--------------------SamstdkMIAK 342 Caenorhabditis ...
EGT47843     299 ----------LSKQRIDELSGPElQLKAHMV--KSHVMKTSEMRRLIDP--------------------NlmsteaMLKE 346
EFP04449     310 ----------LSKQRIDELSSPElQLKAHMV--KSHVMKTSEMRRLIDS--------------------RamstdlMIEQ 357
XP_002642969 302 ----------LSKQRIDELSSPEmKLKAHMV--KSHVMKTSEMRKLIDS--------------------SlmstdaLIQN 349
EDQ86070     318 es-----trlMTLADMKKLPLKD-MLRHFLR--QAEALRYSDICKHVAPgeh----------------------yqLKRL 367
Q4QG17       275 p-------smIIHRFANCKSVAE-QTNQLLQ--RCHILTLQRLQNIVVPytsn----------evvKTMStvpeaqLVEA 334 Leishmania major
Q4CYE9       287 v------arsLLRRYAHRYSVLD-QVLVLLQ--RCQVMKLTELRELVVSpdqtlvppppspstapqQPQGgvtdkqLLEA 357 Trypanosoma cruzi
XP_001415474 255 nantlgdgtgLSKSQLASLPL-DrRIRALFAkgQKSCMKFSRIRQFVTEpie---------------------peqLIAV 312
7A6H_M       314 IQKVAMLVQGNWVVKSDil-------yPKDsssphsgvpAEVLCRGRDFVmw--kfTQSRWVVRKEVATVTKLCA--EDV 382
EFO19660     320 IRECARLVCNIWILKSEll-------yPDE---------ASVLHYARDLVlc--lfSSNLPVRRLDLQMAFGLST--SDL 379
Q23206       343 LKECASLVQGVWVLDSNlmfknlapahSNTagkt-dlyrAELWRNARDLAlc--liDGGHRVTRLTLMTCFKLSE--RDS 417 Caenorhabditis ...
EGT47843     347 LEKCSRLVNGVWVLDSNlmfknlpsvhKNThdl----frAELWRNARDLAlc--liDGGHRVTRSTLITCFKLNE--KDA 418
EFP04449     358 LKQCSRLVNGVWVLDSNlmfqnlppahSNTagkt-dlyrAELWRNARDLAls--liDGGHRVTRLSLMTCFQLNE--RDA 432
XP_002642969 350 LKACSRLVNGVWVLDSNlmfqnlppahSNVagkt-dlyrAELWRNARDLAlc--liDGGHRVTRLSLMTCFKLSD--KDA 424
EDQ86070     368 LPSMALLINGVWVARSPlv-------hPDAcnsfytgapAERMQAARDYAlw--rfAYGKVVTKAQVMKYGKLRE--PDA 436
Q4QG17       335 LKSCAVWLHGVWVSRYC----------DQF---------RGSVAALREVIlarfyqSEDGSVARADFNAWITTSAarRSI 395 Leishmania major
Q4CYE9       358 LREVAVWMHGVWVSKTA----------SRF---------KGTVAALREVIllqffeSEDASLTRSEVNKLVNGTAlrRTV 418 Trypanosoma cruzi
XP_001415474 313 IQDSAHLVQGNWVAKSTlrc-----------------ggNVTWENMRDSAlf--qfARSRNVKPELVSNCLKRNS--TKS 371
7A6H_M       383 KDFLEHMA--VVR-INKG---------WEFI-LPyDG--------EFIKKHPDVVQR----QHMLW--TGIQAKLEK 432
EFO19660     380 DSILKTLNriMVDeHERS---------WKLRh---DDv------eEFGKNKDEL--KvfieEKRYW--HKRWEEIHR 434
Q23206       418 DEILSTFG--VKCeATRS---------WRLR-VErDA--------QFLE--DPAMKKhvveQKAKW--VQKFNELEK 470 Caenorhabditis ele...
EGT47843     419 DEILSTFG--TRCeVSRS---------WKLR-IErDE--------DFLN--DPLMRKyvisEKEKW--IQKFYELDK 471
EFP04449     433 DEILSTFG--VRCeKTRS---------WKLR-IErDD--------EFLK--DPAMKKhviaEKVKW--INTFNELEK 485
XP_002642969 425 DEILSTFG--VKCeAARS---------WKLR-MErDP--------EFLN--DPSMQKhiisEKEKW--IQTFNDLEK 477
EDQ86070     437 GQVLENL---TKQdSSRL---------HHLK-IPeDA--------SFQSSHPDLVKK----M------QPIFIEFQR 482
Q4QG17       396 KEILATVA--VLNtDEPDpsk----rrWRLKyVPeDRaareanlrDFKAKFAAEEAS----QHEAW--RRRCAQVMA 460 Leishmania major
Q4CYE9       419 KEILESVA--TLNsNEPDptk----rvWRLRhVPaDAalrramlqDAENVHRQEVTF----QRMQW--EHFRPHIKA 483 Trypanosoma cruzi
XP_001415474 372 DPTLAKMRreVLAeFSRPrgygsaadgFEFN-EAtDE--------AFEAEFPDVVSR----EMESWlaLAPSLDITL 435
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