Conserved Protein Domain Family
SRP54_euk

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TIGR01425: SRP54_euk 
signal recognition particle protein SRP54
This model represents examples from the eukaryotic cytosol of the signal recognition particle protein component, SRP54. This GTP-binding protein is a component of the eukaryotic signal recognition particle, along with several other protein subunits and a 7S RNA. Some species, including Arabidopsis, have several closely related forms. The extreme C-terminal region is glycine-rich and lower in complexity, poorly conserved between species, and excluded from this model.
Statistics
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Structure
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TIGR01425 is classified as a model that may span more than one domain.
TIGR01425 is the only member of the superfamily cl36902
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P49969     2 VLAQLGGSISRALAQMSNatvIdEKVLGECLNEISRALLQSDVQFKMVRDMQTNIRK---IVNLETLAAGTNKRRIIQQA 78  Hordeum vulgare
O42816     2 VLADLGSRLRGALSSVES---GsDDEIQQMIKDICSALLESDVNVKLVAKLRGNIKNkidESNVSKETSAMNKRKKLQKI 78  Candida albicans
O15821     2 VLSQLGSSLVTALRKMTSstvVdEEVINTLLKEIETSLLGEDVNPIFIRQMVNNIKK---KINSEDIPDGIDKRKLIKDS 78  Entamoeba histolytica
CAA34386   2 VLADLGRKITSALRSLSNatiInEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKS---AIDLEEMASGLNKRKMIQHA 78  house mouse
P49969    79 VFTELCNMLDPGKPA-----------------FTPKKGKPSVVMFVGLQGSGKTTTCTKYAYYHQRKGFKPSLVCADTFR 141 Hordeum vulgare
O42816    79 IFDELCALVDSNVEPpkpkklststktingkkVRLSKESSHVIMFVGLQGAGKTTSCTKLAVYYKKRGFKVGLVCADTFR 158 Candida albicans
O15821    79 VFEELINLVDPKTEA-----------------FKPKKGKTCVLMMVGLQGAGKTTTITKLALYYKNRGYKPAVVGADTFR 141 Entamoeba histolytica
CAA34386  79 VFKELVKLVDPGVKA-----------------WTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFR 141 house mouse
P49969   142 AGAFDQLKQNATKAKIPFYGSYMESDPVKIAVEGLERFRKENSDLIIIDTSGRHKQEAALFEEMRQVAEATKPDLVIFVM 221 Hordeum vulgare
O42816   159 AGAFDQLKQNAIKANIPYYGSYLEPDPVKIAFEGVQKFKQEKFDIIIVDTSGRHRQEEQLFTEMVQIGEAVQPTQTIMVM 238 Candida albicans
O15821   142 AGAYEQLQMNAKRAGVPFFGIKEESDPVKVASEGVRTFRKEKNDIILVDTSGRHKQDKELFKEMQSVRDAIKPDSIIFVM 221 Entamoeba histolytica
CAA34386 142 AGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEERLQVSNAIQPDNIVYVM 221 house mouse
P49969   222 DGSIGQAAFDQAQAFKQSASVGAVIITKLDGHAKGGGALSAVAATKSPVIFIGTGEHIDEFEIFDVKPFVSRLLGMGDLS 301 Hordeum vulgare
O42816   239 DGSIGQAAESQARAFKESSNFGSIILTKMDGHAKGGGAISAVAATKTPIVFIGTGEHVGDLEIFKPTTFISKLLGIGDIQ 318 Candida albicans
O15821   222 DGAIGQAAFGQAKAFKDAVEVGSVIITKLDGHSNGGGALSAVAATKSPIIFIGTGEKVNEIEEFDAESFVRQLLGMGDLK 301 Entamoeba histolytica
CAA34386 222 DASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIE 301 house mouse
P49969   302 GLMDKIQDVMPADQQp--ELLAKLAEGTFTLRLLYEQFQNLLKMGPIGQVFSMLPGFSsELMPKGHEKEGQAKIKRYMTI 379 Hordeum vulgare
O42816   319 GLIEHVQSLNLHQDEghkQTIEHIKEGKFTLRDFQNQMNNFLKMGPLTNIASMIPGLS-NIMSQVGDEETSKKIKNMIYI 397 Candida albicans
O15821   302 GIAKLAKDFAENAEYk--TMVKHLQEGTLTVRDWKEQLSNLQKMGQLGNIMQMI-GLNhPMFQGGNIEK---KFKVFMVI 375 Entamoeba histolytica
CAA34386 302 GLIDKVNELKLDDNE---ALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGtDFMSKGNEQESMARLKKLMTI 378 house mouse
P49969   380 MDSMTAAELDSTNp-KLMTE--SRIIRIARGSGRQIRDVTDMLEEYKRLAKM 428 Hordeum vulgare
O42816   398 MDSMTTKELECDG--RIFIKepSRIVRVARGSGCAVVEVEMILQQHRMMSTM 447 Candida albicans
O15821   376 LDSMTDRELDGSA--KTMLNdeSRIRRLARGSGRDIREVNELFEQIKLFQQC 425 Entamoeba histolytica
CAA34386 379 MDSMNDQELDSTDgaKVFSKqpGRIQRVARGSGVSTRDVQELLTQYTKFAQM 430 house mouse
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