4BV4


Conserved Protein Domain Family
Spaetzle

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pfam16077: Spaetzle 
Spaetzle
This family of proteins are nerve growth factor-like ligands required in the pathway that establishes the dorsal-ventral pattern of the embryo. They form a cystine knot structure.
Statistics
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PSSM-Id: 465007
Aligned: 43 rows
Threshold Bit Score: 95.464
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4BV4_L         9 FLCRSIRKLVYPKKGLRADDTWQLIVN-NDE-----YKQAIQIEECEG-ADQPCDFaanFPQSYNPICKQHYTQQTLASI 81 
EDS28293     222 PLCYSVERLIHPQEGFTKDKINLTIVN-TKE-----YKQGVRVELCSN-PAQTCNEldgLMGQYRTECKQLYHYRTLLAV 294
XP_016663274 167 KFCESREELIFPQAAITKKDEWRYIVQ-DINinntnFKQGIRVEICNAySGAKCKFnglLPLGYTTTCVQKYIYKKLVAI 245
BAH70735     198 TFCESKEDVIFPEAGVTKNNEWRYIIQ-DPNnddpsFRQGIRVEKCID-AGKNCKFnnlLPLGYTSICVQKYIYKKMVAI 275
OWR47524     137 PLCDSYEKTFSPQAALDSNKKWHYILNvKDN-----PIQKFRVEICRS-PDLACSSvayFQNGYEARCVQKYVYRNMVGV 210
XP_028033161 179 ELCDFRVKIMTPLAAQSDDLKWYHVLNfNEN-----PLQGFRVEICNT-TSTGCAKfvtMENNYNPKCVQKFIFRKMKIL 252
EFN77778     120 SLCVSNEKVVFPQSAENTRNEWLFVVN-QDN-----FKQGVRVELCSG-EDQKCSVfdgLVDHYQTMCKQKYISRELVAL 192
EFN66711     175 PLCLSQERVIRPKTAQNLKNEWRFILQ-SNEm---nFSQSVRIETCKE-ENNKCRMidgFAEGYITACKQKYIYRELSAI 249
EGI66251     210 MLCPIREQVVYPQTAQNKQNQWLFIVN-QDD-----LKQGIRIEVCLN-EGQKCDMiedFAEGYKTSCKQKYIYRELAAV 282
EEB19900     344 SLCPIRQEVVFPRAAKNKDDKWLFVVN-QDR-----YVQGVTVEVCLN-PGNRCTLtegFPLGYVPYCKQKYIERRLVAI 416
4BV4_L        82 KSDGElDVVQNSFKIPSCCKC 102
EDS28293     295 HPKTG-ELYKESFKLPSCCKC 314
XP_016663274 246 KDFKE--IYYESFKLPSCCEC 264
BAH70735     276 KDSKE--VYYESFKIPSCCEC 294
OWR47524     211 NENKE--IVEGPFQVPSCCSC 229
XP_028033161 253 SESGE--MIERSMKVPSCCSC 271
EFN77778     193 GANGK--VVTDTFRFPASCCC 211
EFN66711     250 SENDE--IVRDYFSFPASCCC 268
EGI66251     283 GSDGN--IFKDQFRFPSSCCC 301
EEB19900     417 GEDGK--PHTDSFKLPSCCAC 435
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