1JKE,1J7G


Conserved Protein Domain Family
Dtyr_deacylase

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cd00563: Dtyr_deacylase 
Click on image for an interactive view with Cn3D
D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not in archea; beta barrel-like fold structure; forms homodimers in which two surface cavities serve as the active site for tRNA binding
Statistics
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PSSM-Id: 238316
Aligned: 19 rows
Threshold Bit Score: 206.356
Created: 7-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 39 residues -Click on image for an interactive view with Cn3D
Feature 1:dimerization interface [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                           #  ### ####               
1JKE_A      1 MIALIQRVTRASVTVE--------GEVTGEI---GAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAegkmn-----l 64  Escherichia coli
2225963     1 MRVLVQRVSSAAVRVD--------GRVVGAIrpdGQGLVAFVGVTHGDDLDKARRLAEKLWNLRVLADEks--------- 63  Mycobacterium tube...
EAA01130    3 MKAIIQRVTCAKVTVG--------DELVSSI---GRGLCVLVGISSDDNASDVEWMARKLLNLRLFENPstgkrw---se 68  Anopheles gambiae ...
AAL38369    1 MRAVIQRVSSSSVTVD--------GRIVSEI---GPGLLVLIGIHESDTESDADYICRKVLNMRLFSNEttgkgw---dq 66  Arabidopsis thaliana
CAB04731    1 MKVVLQRVTRAAVTVG--------DEVVGSI---GRGLCVLVGVHRDDTEEDMKYIIRKILNLRVFPASeqkpw----dk 65  Caenorhabditis ele...
CAC16475    1 MKAVVQRVTRASVTVG--------GEQISAI---GRGICVLLGISLEDTQKELEHMVRKILNLRVFEDEsgkhw----sk 65  human
Q54235      1 MRAVVQRVDGASVSVAgatddpsaPGVVGEIv--GEGLCVLVGVTHDDTPQKAAQLARKLWSVRVLEGEks--------- 69  Streptomyces griseus
NP_518618   1 MIGLIQRVSQAAVRVD--------GRVVGEI---GPGLLALVCAERGDTVAEADRLLEKLLNYRVFSDAqgkmnlpvrni 69  Ralstonia solanace...
CAB16293    1 MKAVIQRVLNASVSVD--------DKIVSAI---QQGYCILLGVGSDDTPEDVTKLSNKILKLKLFDNAeqpwk-----s 64  Schizosaccharomyce...
Q54088      1 MKLVLQRVKEASVSID--------GKIAGAI---NQGLLLLVGVGPDDAAEDLAYAVRKIVNMRIFSDAdgkmn-----q 64  Streptococcus dysg...
Feature 1                 ## ## ### ##### #                                   ################
1JKE_A     65 nvqQAGGSVLVVSQFTLAADTeRGMRPSFSKGASPDRAEALYDYFVERCRQqe--mnTQTGRFAADMQVSLVNDGPVTFW 142 Escherichia coli
2225963    64 -asDMHAPILVISQFTLYADTaKGRRPSWNAAAPGAVAQPLIAAFAAALRQlg--ahVEAGVFGAHMQVELVNDGPVTVM 140 Mycobacterium tube...
EAA01130   69 svvDLQLEMLCVSQFTLYHRL-KGNRPDFSRAMQGPEAQQLYESLLQRMRNeyaterILDGRFGAMMQVHVVNDGPVTLE 147 Anopheles gambiae ...
AAL38369   67 nvmQRNYGVLLVSQFTLYGFL-KGNKPDFHVAMPPDKAKPFYASLVEKFQKaynpdaVKDGVFGAMMQVNLVNDGPVTMQ 145 Arabidopsis thaliana
CAB04731   66 svmDLDLEVLSVSQFTLYGQF-KGNKLDFHTAMAPTEASKFYASFLEAMKKaykadkIQDGKFAAMMSVDIVNDGPVTVT 144 Caenorhabditis ele...
CAC16475   66 svmDKQYEILCVSQFTLQCVL-KGNKPDFHLAMPTEQAEGFYNSFLEQLRKtyrpelIKDGKFGAYMQVHIQNDGPVTIE 144 human
Q54235     70 -csDVNAPLLVISQFTLYGDArKGRRPTWNAAAPGEVAEPLVDEVVAQLRAlg--arVETGRFGADMRVSLTNHGPFTVI 146 Streptomyces griseus
NP_518618  70 dgnGLAGGLLVVSQFTLAADTkSGTRPSFTPAAAPEAGRRLYEHFVARARQqh--piVATGEFGAMMQVSLVNDGPVTFW 147 Ralstonia solanace...
CAB16293   65 tiaDIQGEILCVSQFTLHARVnKGAKPDFHRSMKGPEAIELYEQVVKTLGEslgsdkIKKGVFGAMMNVQLVNNGPVTIL 144 Schizosaccharomyce...
Q54088     65 siqDIKGSILSVSQFTLYADTkKGNRPAFTGAAKPDMASQFYDRFNEQLADfv---pVERGVFGADMQVSLINDGPVTII 141 Streptococcus dysg...
Feature 1     ## 
1JKE_A    143 LQV 145 Escherichia coli
2225963   141 LEG 143 Mycobacterium tuberculosis H37Rv
EAA01130  148 IES 150 Anopheles gambiae str. PEST
AAL38369  146 LDS 148 Arabidopsis thaliana
CAB04731  145 FDS 147 Caenorhabditis elegans
CAC16475  145 LES 147 human
Q54235    147 IEV 149 Streptomyces griseus
NP_518618 148 LQV 150 Ralstonia solanacearum
CAB16293  145 YDT 147 Schizosaccharomyces pombe
Q54088    142 LDT 144 Streptococcus dysgalactiae subsp. equisimilis

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