1HCN


Conserved Protein Domain Family
GHB

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smart00068: GHB 
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Glycoprotein hormone beta chain homologues.
Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.
Statistics
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Structure
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PubMed ReferencesClick to see Conserved Features Help

smart00068 is a member of the superfamily cl21545.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HCN_B      5 LRPRCRPINATLAVEkeGCPVCITVNTTICAGYCPTMTRVLQGVL--P--A--LPQVVCNyRDVRFESIRLPGCPrgvnP 78  human
Q91120     19 CSFGCHPTNISIQVE--SCGLTEVIYTTICEGQCYHEDLVYISHY--E--R--PEQRICN-GDWSYEVKHIKGCP----V 85  striped sea-bass
O46430     17 WCNGCMLTNITISVEreECEFCISINTTWCSGYCHTRDLVYKDPI--R--P--NVQKTCTfKEFVYETVNLPGCAkqadS 90  silver-gray brusht...
NP_776485  17 CCRSCELTNITITVEkeECGFCISINTTWCAGYCYTRDLVYRDPA--R--P--NIQKTCTfKELVYETVKVPGCAhhadS 90  cattle
NP_776630  18 AMSFCIPTEYMMHVErkECAYCLTINTTVCAGYCMTRDVNGKLFL--PkyA--LSQDVCTyRDFMYKTAEIPGCPrhvtP 93  cattle
NP_990394  18 taSVCAPSEYTIHVEkrECAYCLAINTTICAGFCMTRDSNGKKLLlkS--A--LSQNVCTyKEMFYQTALIPGCPhhtiP 93  chicken
ABB60052   17 CCYSCELTNITIAVEreECEFCITVNATWCSGYCFTRDPVYKYPP--V--S--SVQQTCTfKEVVYETVKIPGCGdhpeS 90  mallard
Q08127     18 vLSICSPVDYTLYVEkpECDFCVAINTTICMGFCYSLDPNVVGPA--V--KrlVVQRGCTyQAVEYRTAELPGCPphvdP 93  European eel
P30971     16 GCFGCHLKNVSIPMEr--CGQRVCIHTTICEGLCFSEDAVFESPD--E--A--PEHRVCN-GDWSYEVKHIQGCP----E 82  killifish
P37205      4 CSYGCHPKNISISVE--SCGITEFILTTICEGQCYLEDPVYIS-------H--DEQKICN-GDWSYEVKHIEGCPv---- 67  Thunnus obesus
1HCN_B     79 VVSYAVALSCQCALCRRSTTDCGGP-KDHPLTCD 111 human
Q91120     86 GVTYPVARNCECTTCNTENTDCGRF-PEDIPSCL 118 striped sea-bass
O46430     91 LYSYPVATACHCGSCDTDSTDCTVR-GLGPSYCS 123 silver-gray brushtail possum
NP_776485  91 LYTYPVATECHCSKCDSDSTDCTVR-GLGPSYCS 123 cattle
NP_776630  94 YFSYPVAISCKCGKCNTDYSDCIHE-AIKTNYCT 126 cattle
NP_990394  94 YYSYPVAISCKCGKCNTDYSDCVHE-KVRTNYCT 126 chicken
ABB60052   91 FYSYPVATECHCETCDTDSTDCTVR-GLGPSYCS 123 mallard
Q08127     94 RFSYPVALHCTCRACDPARDECTHRaSADGDRCS 127 European eel
P30971     83 SITYPVATNCYCSACNTKDTYCTRL-YAHIPSC- 114 killifish
P37205     68 gVTYPVARNCECTACNTGNTYCGRL-PGYVPSCP 100 Thunnus obesus
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