Conserved Protein Domain Family
DUF4818

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pfam16089: DUF4818 
Domain of unknown function (DUF4818)
This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 176 and 214 amino acids in length. There is a single completely conserved residue W that may be functionally important.
Statistics
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PSSM-Id: 465013
Aligned: 29 rows
Threshold Bit Score: 89.962
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EDX16356      32 AAPLLGAWLFSACVVTLLHGVRMFPSALPAdqrfrngnrnlrgnESSWASLLLETGVCCLVLDLTLSKLWHRIESLCQCA 111
XP_002051403  32 PGPTLPTIIVGVAILDLIYDYRIVPLSMYK--------------RARGIKYICECFVAILFLEVGMLIFWQTIEHLVYLI 97 
XP_001963392  30 PGPKLPSVMVTLALMDLIYDNSFVPEKLEG--------------VPRFLKWVYEVIVSVFVLDVGLH-FWKATEYTLYLL 94 
NP_001245542  29 PAPKLPSLFVGLAAMDIIWDNCFVPRKLQK--------------RSAVIRWIYELIVSHLLLGL-VQVFWKPVDNICVIL 93 
XP_002036021  29 PAPQLPSLIVGLAAMDLIWDTCLVPQELHN--------------LPAVIRRMYEVLVSYLLLGIAVQLFWKSVDFMCVIL 94 
XP_002106243  29 PAPKLPSLIVGLAAMDLIWDINLVPRLLQN--------------SPAVIRRLYDVIVSYLLLGLFMG-FWKSVDNICVIL 93 
XP_001993114  32 PAPCQAKWLFGLSLVLLLWRCELLPKRYAS--------------VYPRIHTCVELLGSVFVSELAMLIGWCSYERLVHQL 97 
XP_001964851  31 PAPSLGAYLFLLAILFLLWDGDVIPKRYKK--------------SSPRLFAFVEILATVFITELIMLIGWCGYERMAFKT 96 
Q9VLE7        31 AAPPVGKYIFLLAILLLFWDSDMIPRKLKP--------------FSPRIFACGDLLFTIFFTEIILLVGWCGLERMTYRF 96  fruit fly
NP_001163770  32 PAPKVGAWIFTFAILLLVADVRMCPKGYTH--------------VPYIIQVLGETVGSLIIIEFSTSVVWCALESVTHQL 97 
EDX16356     112 IVGIL-QALAVEEQTFLACEYWTLGLTTGLIGGCLLWLSLWATALPQKLRC 161
XP_002051403  98 AKMLLlEMDIVSLDYYYRHETFIIGSFTLPISLGILVLVSRITNHFKMLSR 148
XP_001963392  95 LKIIVlWMGYVSHLTYIEYEYYCQAAMTLPLAFLVLTFAGHATNHFHLVRG 145
NP_001245542  94 MRLIIlGTGIVSETNYENYESYWVGFLTVPLSLLILAIAGQATDHFSVLRA 144
XP_002036021  95 MRDIIlGNGLVSKIDYNNYESYWVGMITVPLSLLILGSAGHGIDYFHMLHD 145
XP_002106243  94 LRILIiGTGHVSESNYENYESHWVGTVTVPLSLLILAFAGEATGHFPVLRR 144
XP_001993114  98 SHLIC----LNLNLNCRWCEYFTLGMLTLLPSGLLLFTLAPAQWREFLVQL 144
XP_001964851  97 ASMIC--------RQSEWCEYGLLIIITILGALITMCIVAEVVCPVKMKDT 139
Q9VLE7        97 IFSVC--------RGKPGCNYGLMTFCSILGAVGSLCIVLEVLTQRKMKNL 139 fruit fly
NP_001163770  98 TRLLL-LYWGMNGDTYLALEYWILLIPTTAVASTFLYIMIKAIIpy----- 142
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