Conserved Protein Domain Family
ARGLU

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pfam15346: ARGLU 
Arginine and glutamate-rich 1
ARGLU, arginine and glutamate-rich 1 protein family, is required for the oestrogen-dependent expression of ESR1 target genes. It functions in cooperation with MED1. The family of proteins is found in eukaryotes.
Statistics
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PSSM-Id: 405931
Aligned: 17 rows
Threshold Bit Score: 64.302
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFJ22833      58 QEAELKLIEEETTRRVDEAIRKRVQEVLD--SDEIQKEIQMRIDEGRKKMIEDVNAQLAREREAALRATRTKE------- 128
EEC07884       4 KEVDSKKAEDDMHRRIEEAVAMRVQEEMErrKEAMETEVRRRVEEARHHMEKQLMQEIEQRRSQMMAEHKLKEvgptvlg 83 
XP_018647859  73 RWAESKLLEEEVARRLERYLDSELAKLLVlrRVQFNAEIERRVEAERTEVLRRRAEEAERKAKEEAEALQRRE------- 145
CDS36951      62 QWAESKLLEEEVARRLERYLEAELAVLLKerEAEFNAEVERRVAIEREALEKRRKEEAERKAREEEEEKHRKE------- 134
EFJ45847     250 aELQSRLVAEELERRVAAYVEERVAAVLN--SEAVQRELQTRLERERRAIEEQVERELVAERERAAREEEARR------- 320
XP_002889840  75 QEAELKLIEEETVKRVEEAIRKKIEESLQ--SEKIKLEILTLLEEGRKRLDEEVAAQLEKEKEASLIEAKEKE------- 145
XP_009380262 113 KEAELRILEEETARRIEEAIRKKVEESLN--SEEIKLEIQRRIEEGHKKLLDEVAAQLEKEKEAALIEARQKA------- 183
XP_009121769  82 HEAELKRLEEETARRIEEAVRKNVEERMN--TEEVKEEIERRTKEAYEKMLLDVEIQLKNEKQSALNEARRKE------- 152
XP_026690893 119 KELEEKMIEDETAKRVEELVKKRVEEELEkrKDEIEKEVLRRVEEMKHIMEKQMLEEMERQKLAELQARQAKE------- 191
EKC31426      63 KELEEKLIEEEVARRVEELVAKRVEEELErrKDEIEAEVRRRVEEAKKIMEKQMLEELERQREAELEAQKKKE------- 135
EFJ22833     129 -----EQERKDKEDLDRMLEENKRKVEEAQKREAeerarkeEERYRELEAIQRQKDEIMRRRKLEEELEREEQMKILGKK 203
EEC07884      84 rssrnEEERKRLQELERTLEENSRKLEEAQRKLA-------EERLAMVEERRRLDEARRKLEQEQEKKMRQDQQVILNKG 156
XP_018647859 146 -----EEEKRLKEVSERLAQERERELEEQRRLEE-------EAERKRCEAELRELEERQRREAEELQRIKREQEIILNKK 213
CDS36951     135 -----EEERQLKELNERLARQREEELSELRRKEE-------EVRQKQYEEELRKLEEKQRLEAEEQRRIKKEQEIILNRK 202
EFJ45847     321 -----EAIRAQQQELEELELERKKEEEEAAKRRReeearqlEQHFLELQRKQQAKMEEEERKKKEDEDLKRQQQLILGKG 395
XP_002889840 146 -----EREQQEKEESERIAEENLKRVEEAQRKEAmerqrkeEERYRELEELQRQKEEAMRRKKAEEEEERLKQMKLLGKN 220
XP_009380262 184 -----EQERKEREELDKMLEENQRRVEESQRREAleqqqkeLERCLELEHLQKEKEEAMRRKKMWEEEEKANQMKLLGKN 258
XP_009121769 153 -----EQARREREELDKMLEENSRRVEESQRREAlelqrkeEERYRELELIQRQKEEAARRKKLEEEEEIRNSSKVSNGS 227
XP_026690893 192 -----EEETQKRTQLEEILKENDRKMKEAEERMN-------EERLAMVEQQRLIHEERMRMEEDRKKQRRAEQNVILGKK 259
EKC31426     136 -----EEEKLKRKELEEIMAENNKKIEEAQKKLA-------EEQLKLVEEQRRMLEEKQRMEEEDRKRKKREQEVILNKK 203
EFJ22833     204 NARPKLSFAL 213
EEC07884     157 KVRPKLSFSL 166
XP_018647859 214 RIRPKLSFTL 223
CDS36951     203 RVRPKLSFTL 212
EFJ45847     396 --RKKMSFSL 403
XP_002889840 221 KSRPKLSFAL 230
XP_009380262 259 KSRPKLSFAi 268
XP_009121769 228 RSRSKLHFGM 237
XP_026690893 260 NTRPKLSFSL 269
EKC31426     204 NARPKLSFSL 213
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