2EVE,2AR1,2GBS,3EOP


Conserved Protein Domain Family
EVE
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cd21133: EVE 
EVE domains are putative RNA-binding domains that belong to the PUA superfamily
The EVE domain, formerly known as DUF55, has been revealed via structural similarity to be part of the PUA superfamily. It is most similar in three-dimensional fold to the YTH (YT521-B homology) domain, and is thought to be involved in RNA-binding.
Links
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Statistics
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PSSM-Id: 410978
Aligned: 92 rows
Threshold Bit Score: 147.321
Created: 27-Jan-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Download Cn3D
 
putative RNA
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1: putative RNA binding site [nucleic acid binding site], 1 residue position
Conserved feature residue pattern:WClick to see conserved feature residue pattern help
Evidence:
  • Comment:The conserved tryptophan residue may be essential for recognizing N1-methyladenosine in bound RNA
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                   #                                                    
2EVE_A         2 AYWLXKSEPDeFSISDLQrl---gkARWDGVrnYQARNFLRTxaegDEFFFYHSsc--pePGIAGIGKIvKTAYPDPtal 76  Pseudomonas syr...
Q2GIJ6         5 RFWLLKSEPAdFAWGDMLav---cvTTWDGVknYQAQGNLKAasvgDFAFFYHAga---eKAIKGIVKVcREFYIPEnd- 77  Anaplasma phago...
Q2IM08        10 AYWLLKTEPGtYAWSDLVad---gtTPWTGVanPQAQANLRAmkagDRAIVYHSg----eKRAVGIAEVvRTAYPDPtag 82  Anaeromyxobacte...
Q024K9         2 KYFLAKTEPSvYSIDDLErd---qeTVWDGVtnPQAVRAILNmktgDRVFIYHSgg---vSAIVGMAAVrSDGRPDPkn- 74  Candidatus Soli...
Q1D7F1         5 QYWLIKSEPSvYAYAQLEkd---gkTEWTGVrnFEARNNIRAmkpgDLCLYYHSne---dKAVVGVAQVlTPPGPDStvp 78  Myxococcus xant...
WP_081722220   5 QYWLVKQEPEsYAWETFVrd---grTTWDGVrnFQARNNLKAmregDRVLFYASvs---tKAVLGTARVsRTAFPDPtvd 78  Geminisphaera c...
YP_001636964   3 NYWLLKTEPTvYSFADLVre---grTVWDGVsnNVALKHMREmrsgDEALIYHTgd---eRQAVGLAQVvSDPYPDPkqs 76  Chloroflexus au...
XP_024385998  65 GYWLLKTEPGeWGWADQEkng--giSNWDGVrnALAQKHLRSmqlgDHAFFYHSgk---gPSVVGVVEVvKVAYPDNtde 139 Physcomitrella ...
NP_565364      6 RYWLLKTEPNeWSWSDQEsng--giSKWDGVknKQAQKNLKSmtlgDLCFFYHSgt--ksRCVVGVVEVsREWYTDDaeg 81  thale cress
BAF12802      18 KYWLLKTEPGeWSWSDQArapgggvAPWDGVrnRQAVNGLRAmrvgDRCLFYHSgagaasRRVVGVVEVaREWYEGEgea 97  Japanese rice

Feature 1                                                                                        
2EVE_A        77 dpdshyhdakatteknpWSALDIGFVDIFknVLGLGYLKqqsqleq-------lplvqkgSRLSVXPVT--AEQWAAILA 147 Pseudomonas syr...
Q2GIJ6        78 ----------------rFGCIDVEFHSALkrSISLQEIKsveslss--------mailkqPRLSVSEVT--PAEWDTIIE 131 Anaplasma phago...
Q2IM08        83 ---------------geLVCVDVKAVEPLpaPVPLEALKlepafeg--------svllrqGRLSVVPLA--PAEWRDLAA 137 Anaeromyxobacte...
Q024K9        75 ---------------pkSAIVDLAFAVKFehQLTLTEIKqtgefdd--------walvrqGRLSTMEVPekFVEWFHEHA 131 Candidatus Soli...
Q1D7F1        79 --------------dedWAATFMGPVVPFtqPVDLATIKataalkd--------fplvtrGRLSVAPVT--ATHFKQVLK 134 Myxococcus xant...
WP_081722220  79 adea------rsggregWLAVELEAGQALakPVTLEAIKaeasltd--------iallrqSRLSVMPLT--REEFETIVA 142 Geminisphaera c...
YP_001636964  77 --------------dprLIVVDVVPLRALphPVSLNDIKadpffad--------falvrqGRLSVVPVS--AAQWERLLA 132 Chloroflexus au...
XP_024385998 140 --------------sgkSCMVDVRALAALpkPVPLSAIKnveelrd--------willrqSRLSVMPVS--PDEWQRVCE 195 Physcomitrella ...
NP_565364     82 --------------vegEGAVDVKAIGEMrkCVDLKEMKgdkgiitk------gfvlfrqPRLSVVPVE--EDVWNMICE 139 thale cress
BAF12802      98 ---------------asGGAVDVRAVGEFrrPVALGEIKkaagggggevegmrefallrqPRLSVMPVP--AKVWDWICE 160 Japanese rice

Feature 1         
2EVE_A       148 L 148 Pseudomonas syringae pv. tomato str. DC3000
Q2GIJ6       132 M 132 Anaplasma phagocytophilum str. HZ
Q2IM08       138 L 138 Anaeromyxobacter dehalogenans 2CP-C
Q024K9       132 H 132 Candidatus Solibacter usitatus Ellin6076
Q1D7F1       135 M 135 Myxococcus xanthus DK 1622
WP_081722220 143 L 143 Geminisphaera colitermitum
YP_001636964 133 M 133 Chloroflexus aurantiacus J-10-fl
XP_024385998 196 L 196 Physcomitrella patens
NP_565364    140 L 140 thale cress
BAF12802     161 M 161 Japanese rice

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