Conserved Protein Domain Family
DUF4702

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pfam15774: DUF4702 
Domain of unknown function (DUF4702)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 346 and 637 amino acids in length.
Statistics
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PSSM-Id: 464862
Aligned: 10 rows
Threshold Bit Score: 510.922
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGW09579       1 MTSLSVQ--MQ--LPKKHRLPGREPTFKSGHVPHLPSMYR---YSEHQGQQQNLRPPQVFGTFLDFLTEGQVLDSLQTVV 73 
2_pfamImport   1 HTTYMAR--VQ--PPRKPLFPEMRPTSKLGHEPHPPSLYGpsgSSVLRGHRRSAWGTQPFGSFLDFLVKGQVLDSLQTVV 76 
Q80X53        18 HSTYVA----P--LPKKHLLPEMRPTCKLGRVPHLPSMNQ---YSEHQSHQQNFRHPLAFGGFLDFLTEGQVLDSLQTVV 88  house mouse
EFB28386       5 QLPKKP----L--FPEMGQASKSGHMPHPPSRYTPTDSLGlrgHRRNPRDPRPFGTFLDFLVESQVLDSLQTVVEEATER 78 
XP_020930092  18 PTTYVPR--VQ--PPKKPLFPERGPASKVGHMPHPPSMHSpvsSSGLRGHCRNLKGSRPFRNFLDFLVEGQVLDSLQTVV 93 
ELK15579      18 HTTYLAR--VQ--PHKKPAFPEMGQASKLGHVPHPPSMYGpsgSSGLHSHRRNSKGPRPFGSFLDFLVEGQVLDSLQTVV 93 
PNJ13870      18 HSMCSAR--VQ--LPKKPLVPEMGPACKPGRVPHLPSTCG---SSALQGQRRNKRHPQPFGHFLDFLTESQVLDSLETVV 90 
XP_017205049  18 HSPYVA----RvqSLKKPPLPQMGSA----RVPPPRFTQG---TSAQPGPHRDTKGPQSFGSFLDFLTEGQVLESLQTVV 86  rabbit
XP_003801772  18 HSTYVAR--VP--PPKKSVFLDMGPTFKLGHEPHSPSTYA---SSVLRCHRQKRTAPQPFGSFLDFLTEGQVLESLQTVV 90  small-eared galago
XP_023416439  18 HSTY--KarVP--PRKKPLLPEMRPAFKLGHVPHPPAMDG---SSAYQGHCQTPKRPQPFGSFLDFLTEGQVMESLQTVV 90  domestic guinea...
EGW09579      74 EKATEHLAATKTEAGVPLVDIQDPLEAP-S-DRRTRAR---RTVHRHHARPTLCAGHPNNYPSCSSSMSDSHSSISAGWL 148
2_pfamImport  77 EEATERVAAMKTEAGEPLVEVQDPMETY-SkGQRARARpspSTVYRHRMRPSLCTGHLNNYPSCSSSGSDSRSSLSAGGL 155
Q80X53        89 EQATERLAAMKTEAGVPLVDIQDPVEVP-SsRHRSRARpsiDTVHRHRARPTLCAGRPNNYPSCSSSMSDSHSSITAGWL 167 house mouse
EFB28386      79 MTTMKTEAGVPLVEVQDPIEVPRGGQRV-RaRPSLSTVhqhRARPSLCTGCPNNYPSSSSPMSDSHSSFTAGWLGSPSRH 157
XP_020930092  94 EVATERMATMKTGAGLPLVEIQDPVEVP-KvGRRACSRpslSTVHRHRTRPSLCVGHPNNYPSCSSSMSDSHSSFRACWP 172
ELK15579      94 EKATERMATMKTEAGVPLVEVQDPVEVP-RgGRRVRARpslSTMHRHRVRPSLCIGNPNNYPSCSSSMSDSHSNFTAGWP 172
PNJ13870      91 EKATERMAAMKTEAGVPLVEVQDPVEVP-SgGRRAHARpslSTVHRHRVQPTLCTGHPNNYPSSSSSMSNCHSSLMAGYL 169
XP_017205049  87 EEATERMATMKTGAGVPLVEVRDPVVEPaSgGRRPRARptwSTVCRNRAQPSLCVGRPNNYPSRSSSVSDSRSSLTAGWL 166 rabbit
XP_003801772  91 EEAAERMAAMKTEAGLPLVEVQDPMEMP-SvRHRVHARpnlKTVRRHRAQPSLCVGRPNNYPSCSSSMSDSHSSLMAGCL 169 small-eared galago
XP_023416439  91 EEAAERIASMKTEAGVPLVEVQDFIEVP-SgKRQVRARpsfSTVKRHRIRPSLCTGRPNNYPSCSSSLSDSHSSLTAG-- 167 domestic guinea...
EGW09579     149 GSHNQDTAPGPRGIGSLPPMRDKLLLEKNLKRLLRLENKGKGLNHSCPQRDSLPWDSLDSQTSSQWTREQPLSWFSGLLG 228
2_pfamImport 156 GLRSHDNDLGAHGVGPLPPMRDRLLLERNLKRLLWLENKGKGQSKPSSQRDSLLWDSMGSQASSQWTPDQPPSWFSGLLG 235
Q80X53       168 GSHSQDSDLGARGIGSLPPMRDKLLLEKNLKRLLRLENKGKILNQSCSQRDSLLWDSLGSQTSSQWTREQPLSWFSGLLG 247 house mouse
EFB28386     158 SDLGTQGMGSLPPMRDRLLLEKNLKRLLKLENRGKGLGQSCFRRDSLLWDSLGSQASSQWTQEPPPSWFSGLLDSSTGTP 237
XP_020930092 173 GSQCRDSALDAHSLGPLPAVKDRLLLEKSLKRLLQLENRGKGLGQCCSHRDSLPWDSLDSQASSQWTPETPLSWFSGLLG 252
ELK15579     173 GSHSRDSDMGYHGLGPLPPRRDKLLQEKSLKRLLRLENRGKSLGQSS-QRDSLLWDSMGSQSSSQWTPKQPLSWFSGLLG 251
PNJ13870     170 GSHSRDSDLGAQGLGSLPPVRDKLLLEKNLKRLLQLERKGKGLSQSCSQRDSLLWDSLGSQTSFQWTQEQPLSWFSGLLG 249
XP_017205049 167 GSHGQGSDLGARGSGSLPPLKDRLLLEQSLKRLLKLERKGKSRSQP-SRKDSLRWDSLGSQTTSQWSPEQPLSWFSDLLS 245 rabbit
XP_003801772 170 DSHSRDSDLGAHGLGPLPPMRDKLLLEKNLKRLLRLENKGKGLSQSCSRRDSLPWDSLDSQTSSLGNREQPLSWFSGLLG 249 small-eared galago
XP_023416439 168 ----QDGDLGPQGLGSLPPMRDKLLLEKNLKRLLQLENKGKGWSQSCSKRNSLLLNSLGSQTGSHWTQEQPLSWFSGLLG 243 domestic guinea...
EGW09579     229 SNSATPET--LGLGEQEMIFLKEELTKEIKSLLNQPASFNLPVYCSLREPHRTLDFLAEHRLFPALQRVVSQAVDKLSHA 306
2_pfamImport 236 SGSGTPAAsdLGPTERELIFLKREFNKEMKSLLSQPASFDLPPYCSAREPYHTLDFLAKHHLFPALQRVIHQAVDKLSGA 315
Q80X53       248 SSPATPETseLGLGEQEMIFLKQKLNKEMKSLLNQPRPFNLPTYCPLREPHHTLDFLAKHRLFPALQRVVSQAVDKLSHA 327 house mouse
EFB28386     238 QTSEPRPGeqELTFLKREFDKEIKSLLSQPASFDLPGYCSFREPHQTLDFLAEHHLFPALQSVVCQAVDKLSGARRRDGY 317
XP_020930092 253 SSSGTLEAseLGPGEQELVFLKREFNKQIKSLLSQPVAFDLPGYCAIREPHRTLDFLAEHHLFPALQNVVSQAVDKLSGA 332
ELK15579     252 SSSGTPEVsdLGPTERELIFLKREFNKEIKSLLSQPTSFDLPGYCSLREPHRTLDFLAEHRLFPALQNVVNQAADKLSGA 331
PNJ13870     250 SSSGVPEAsePRPGEQEPIFRKREFNKEIKSLLSQLESLDLPGYCPLREPHRTLNFLADHRLFPALQSVVSQAVDKLRGA 329
XP_017205049 246 SSTGTPEAsgQTPSEEELSFLKQEFDKKLMALLSQPAALDLPGYCSLRQPHCTLDFLAQHHLFPALQSVVSQAVDKLSGA 325 rabbit
XP_003801772 250 SSSDIPEAsdLGPGEQELIFLRREFNKELKSRLSQLSSFNLPGYCSLREPHHTLDFLAKHQLFPALQSVVSQAVDKLSGA 329 small-eared galago
XP_023416439 244 STSGMPDAseLGPREQELIFLKGKCNKEKKSLLSQPTSFDLPGYCILREPHQTLDFLAKHHLFPALQSVISQGANKLRAA 323 domestic guinea...
EGW09579     307 CRHNGFPLFPVDSDPTPVMpgDYDLLQqNESKPNSRDG--------EEPSD-S-PTTVSSPKTSRRKS-------KGRRD 369
2_pfamImport 316 CRPDGCPLFPMAYESTPEP--EPEPPP-GSMPSSPDEDpnd---geEEPYE-SlPTSVSSPKMGYRKSakgrgwgKVKEG 388
Q80X53       328 CRHNGFPLFPVTSETIPDLpgNSDLLQpSSKASIPTNRea-----rGEPCD-Sl-TTAYSPKTSHRKS-------KGRRG 393 house mouse
EFB28386     318 PLFPSEWEPATEPNSDSTP--GSKPAT-PTDGEEPYDV--------LPTQV-SsSKMIRRKSAKGRGRakpkeggSPVSR 385
XP_020930092 333 CRRNGRPLFPSEWEPTTES---------NSKLATPTNG--------EEPDN-LlPTTASSPKVDHRKNvkprgrsKPKGG 394
ELK15579     332 RRQNGCPLFPSEWEPTTEP--NLEVMP-GSEGASLTEG--------EEPYSySlPTTTSSLKMVHRKSikskgggKPKEG 400
PNJ13870     330 RCRNGRPLFPTSLEPTSELqvDGNLPPlGSEPATPTNG--------GQPQA-SpRPTVSSPKMLQRKR-------KDRGG 393
XP_017205049 326 RRHDGCPLFPANAEASSELplHYNLLPpGSQLASPTDK--------EEAA--SpNTTTSIPRTERRKS-------KGTRG 388 rabbit
XP_003801772 330 YRRDGCPLFPANFQGTSELpsDFIEPPlAGRRSSPNSKlaetttdrEEPCN-SlHTTVSSPKMTSKKT-------KGKQV 401 small-eared galago
XP_023416439 324 RCRDGCPLFPT--KPASPFpvNYSQGLpDSK---PAEG--------KEPCD-SfHTTDASLH-----G-------KISRL 377 domestic guinea...
EGW09579     370 SPSMSNAQMTTKFRLKSPS 388
2_pfamImport 389 GSPVSGTQVATKFRLKVTP 407
Q80X53       394 SPP-NAVQMATRFRLKVTP 411 house mouse
EFB28386     386 AQVATRCRIKSPSYKFMRK 404
XP_020930092 395 GSPVSSIQVDTRFRLEMTP 413
ELK15579     401 GSPMSSTQGATRFRLQVTP 419
PNJ13870     394 SPSMSSAQVATRFKLKSPR 412
XP_017205049 389 SPSMTS---ATRFKLKssn 404 rabbit
XP_003801772 402 TPSVLSAPVTTRFRFKETP 420 small-eared galago
XP_023416439 378 NSPSVSNQVGNRVKLKVTT 396 domestic guinea pig
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