Conserved Protein Domain Family
Cast

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pfam10174: Cast 
RIM-binding protein of the cytomatrix active zone
This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Statistics
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PSSM-Id: 431111
Aligned: 12 rows
Threshold Bit Score: 821.76
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q811U3        154 LQTQLKEVLRENDLLRKDVEV-KESKLSSSMNSIkTFWSPELKKERALRKDEASKITIWKEQYRvvqe--------enqH 224  Norway rat
9_pfamImport    1 GGDFILQLQQDNESLRREIDI-KESKLQANMNSIkTFWSPELKKERALRKEESNQIATLKEQWK---------------H 64  
XP_009296283  160 LQAQLKEVLRENELLRKEIEV-KESKLSSSMSSIkSFWSPELKKERALRKDEASKISVWKEQYRavqd--------etqH 230 
Q6PH08        150 LQAQLKELQRENDLLRKELDI-KDSKLGSSMNSIkTFWSPELKKERVLRKEEAARMSVLKEQMRvshe--------enqH 220  house mouse
1_pfamImport    1 LQAQLKDLQRENDLLRKELDI-KDSKLGSSMNSIkTFWSPELKKERVLRKEEAARMSVLKEQMRvthe--------enqQ 71  
8_pfamImport    1 LQCQLRELQRENDNLRRELDTgRDARTGPSMNNV-NFWSPDVKRDRGVRREEAGRTSVLRDQYRtnqddlqpgdirrnkQ 79  
XP_031143341  156 MQVQLRDMQRENELLRRELDL-KDSKLGSSTNSIkSFWSPELKKERIMRKEEAARTSILKEQMRvtheenqlldarrtkH 234  pikeperch
XP_022538566  150 LQAQFRDMQRENELLRRELDL-KESKLGSSANSIkSFWSPELKKERVMRKEEAARTSVLKEQMRvthe--------enqH 220  Mexican tetra
XP_023812415  216 LQAQLRDLRRENDSLRRELDGgRDGKTGHNMNSV-NFWSPEPKRDKGVRREEGLRPSAPKDHYRlsqe--------dsqH 286  Japanese medaka
XP_029317698  171 LQTQLREVLRENELLGRELEA-KESKLSSSMNSIkTFWSPELKKERALRKDEATKMSLWKEQYRvvqe--------etqH 241  Cottoperca gobio
XP_026010553  219 LHSQLRDLQRENNNLRRELEGgRDGRTGPSMNSV-NFWSPDGKREKGVRREEGARSSIVKDQHRtnqedlqpgnnrrnkQ 297  eastern happy
XP_018670964   53 GGDFILQLQQDLESLRREIDI-KESKLQSNMNSIkTFWSPELKKERALRKEERNQIVTLKEQLKvtqe--------enqH 123  vase tunicate
Q811U3        225 ---------MQMTIQALQDELRIQRDLN---------------------------------------------------- 243  Norway rat
9_pfamImport   65 ---------LHLTMQALQDELRAQRDLN---------------------------------------------------- 83  
XP_009296283  231 ---------LQTTVQALQAELRIQRDLN---------------------------------------------------- 249 
Q6PH08        221 ---------LQLTIQALQDELRTQRDLN---------------------------------------------------- 239  house mouse
1_pfamImport   72 ---------KEYQMNNIQDTKRTAIHINps-------------------------------------------------- 92  
8_pfamImport   80 ---------LPLTVQELQEELKAHRDMN---------------------------------------------------- 98  
XP_031143341  235 ---------LQMTIQALQDELRTQRDLN---------------------------------------------------- 253  pikeperch
XP_022538566  221 mldarrtkhLQMTIQALQDELRTQRDLN---------------------------------------------------- 248  Mexican tetra
XP_023812415  287 ---------LPLTVQELQEELRAHKEMNsrlqqqqqhgnsyrehhmdqdfrgrpspghsprqspstlhspasknspka-- 355  Japanese medaka
XP_029317698  242 ---------FQCTIQALQDELRIQRDLN---------------------------------------------------- 260  Cottoperca gobio
XP_026010553  298 ---------LPLTVQELQEELRAHREMNsrsqqhrqqgnsyrelhmdqdlrgglspghsprqspsnlqspgpkssprasp 368  eastern happy
XP_018670964  124 ---------LHLTTQALQDELRAQRDLN---------------------------------------------------- 142  vase tunicate
Q811U3        244 -------------------------------------------------------------QLFQQD--S---------- 250  Norway rat
9_pfamImport   84 -------------------------------------------------------------QLLHDDftM---------- 92  
XP_009296283  250 -------------------------------------------------------------QLLQPP------------- 255 
Q6PH08        240 -------------------------------------------------------------HLLQQE------------- 245  house mouse
1_pfamImport   93 -----------------------------------------------------------twHMLTSE------------- 100 
8_pfamImport   99 -------------------------------------------------------------SRLQQQrqQvp-------- 109 
XP_031143341  254 -------------------------------------------------------------HLLQQE--G---------- 260  pikeperch
XP_022538566  249 -------------------------------------------------------------HLLQQEs-S---------- 256  Mexican tetra
XP_023812415  356 ------------spsntynsrqqeadiiihspgygcntavatqrlspantlqpglknssnlSLYNPNytTgvvpscnslr 423  Japanese medaka
XP_029317698  261 -------------------------------------------------------------QLFQSDysE---------- 269  Cottoperca gobio
XP_026010553  369 sntynprqqeadiiihspgygcntavaaqrispadtlqrglrsspnqplyspsqgpgivpsSGSLHPcsP---------- 438  eastern happy
XP_018670964  143 -------------------------------------------------------------QLLHEDfvT---------- 151  vase tunicate
Q811U3        251 ----SSRTGEPcvaeltee------nfqrlhaeHERQAKELFL--LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 318  Norway rat
9_pfamImport   93 ----NPVDTEN----------------------YERTVRENEL--LQSTLEELETRIEAQRQTLETRDESVRKLLEMVQC 144 
XP_009296283  256 --------GEPlace--------------pseeQERQARELFL--LRRTLEEMELRMEAQRQTLVARDDSVKKLLEMLHS 311 
Q6PH08        246 ----SGNRGAEhftieltee-----nfrrlqaeHDRQAKELFL--LRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS 314  house mouse
1_pfamImport  101 ----TGRGGQEkrwtkalseiewrvmrrrsedvHDRRSESLELcrLRPSLWHLEIRFTVRKGSMNSTFLQCKELSATLQM 176 
8_pfamImport  110 ---gCDGFSSPppvdqsee------nfyrlqseRERQIKELFL--LRKTVEEMEMRMDSQKQTLGARDESIQRLLEMLQG 178 
XP_031143341  261 ----GNRSASDhfttielte----enfrrlqaeHDRQAKELFL--LRKTLEEMELRIETQKQTLGARDESIKKLLEMLQS 330  pikeperch
XP_022538566  257 ----SRGSGAEhfttielte----enfrrlqaeHDRQAKELFL--LRKTLEEMELRIETQKQTLGARDESIKKLLEMLQS 326  Mexican tetra
XP_023812415  424 prspCQVPRCDgfssprldps--eenffrlqseHDRQAKELSL--LRKTMEEMETRINSQKQTLGARDESIQKLLEMLQG 499  Japanese medaka
XP_029317698  270 ----SGHLGHQpippqemte----enflhlhgeYERHVKELFL--LRKTVEEMELRIDTQKHTLTARDESIKKLLEMLQS 339  Cottoperca gobio
XP_026010553  439 ----CQVPGCDgfssppplvps-eenffqlqseHERQAKELSL--LRKTMEEMEMRIDSQKQTLGARDESIQRLLEMLQG 511  eastern happy
XP_018670964  152 ----SPSDGGDkestr------------imqdnYDRLLRENEL--LQSTMEELESRIEAQRQTLGTRDESVRKLLEMLQC 213  vase tunicate
Q811U3        319 KGLSAka----tEEDHERTRRLAEAEMHVHHLESLLeqkekENNMLREEMHRRFENAPD--SAKTKALQTVIEMK----- 387  Norway rat
9_pfamImport  145 KGLPKpdd--ggSDTDALRAQIVGYEARLASMEGLLqekkmELQKFKVSIKSKYSGSNDgmSSNIEAYRQLLEAK----- 217 
XP_009296283  312 KGPSAka----sEEDHERTRRLADAEMHAHHLENLLeqrdkELVALREELHRRLEGTPE--TTKTKALQTVIEMK----- 380 
Q6PH08        315 KGLPSks----lEDDNERTRRMAEAESQVSHLEVILdqkekENIHLREELHRRSQLQPE--PAKTKALQTVIEMK----- 383  house mouse
1_pfamImport  177 KALTKks----iFFKSERTRRMAEAESQVNHLEVILdqkekENLHLREELHRRNQVQQE--PAKTKALQTVIEMK----- 245 
8_pfamImport  179 QGHGPgq----gQGHWGRGQRPGIIAMAAQEAEAQL-----ENIHVREELHRRNQLQAD--PANTRALQTVIDMK----- 242 
XP_031143341  331 KGLPPgpgrvseEEEQERARRIAEAEAQLGHLEVILdqkekENIHLREELHRRNQLHQD--PSKTKALQTIIEMK----- 403  pikeperch
XP_022538566  327 KGLPPvagraseEEEQDRARRIAEAEAQLGHLEVILdqkekENIHLREELHRRNQLHQD--PSKTKALQTIIEMK----- 399  Mexican tetra
XP_023812415  500 QGQAQ--------GHWGRGQRTGIITMAAQEAEAQL-----ENMHVRE-------------------------------- 534  Japanese medaka
XP_029317698  340 KGLSSra----tEEDHERTRRLADAEMTIHQLEGLLeqkdkEMLQLREELHRRYEAAPE--STKTKALQTVIEMK----- 408  Cottoperca gobio
XP_026010553  512 QSQGQg------QGHWGRGQRTGIITMAAQEAEAQL-----ENVHLREELHRRNQLQAD--PAKTRALQTVIDMKattpp 578  eastern happy
XP_018670964  214 KGLPKsddeglnVEVDSMKAQIIGYQSRLGHMESLLhdkniE------VQQYKNRCLDG--NEETSTIHKVIDAK----- 280  vase tunicate
Q811U3        388 ----------DSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNK------------------ 439  Norway rat
9_pfamImport  218 ----------ESKILSLERSNHELELELESVNHNAEVGMTQHNEDMKQLEVVKSHADFMKHK------------------ 269 
XP_009296283  381 ----------DSQIGSLERGLRELEDQVMMLRSSSMLSCEERQEEAKQMEVYRNHTKFMKNK------------------ 432 
Q6PH08        384 ----------DTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTK------------------ 435  house mouse
1_pfamImport  246 ----------DTKIASLERNIRDLEDEIQMLKTNGLLNTEDREEEIKQMEVYKSHSKFMKNK------------------ 297 
8_pfamImport  243 ----------DTKISSLERNIRDLEDEVQMLKTSGLLHPYDRQDELKQVEVYKSHSKFMKSK------------------ 294 
XP_031143341  404 ----------DTKIASLERNIRDLEDEIQMLKANGLLNTEDREEEIKQMEVYKNHSKFMKNK------------------ 455  pikeperch
XP_022538566  400 ----------------VKRVY--SSQLQNTDYTTLLHHYII---EIKQMEVYKNHSKFMKSK------------------ 440  Mexican tetra
XP_023812415  535 ----------DTKISSLERNIRDLEDDVQMLKTSGVLHSDDRHSELKQVEVYNSHSKFMKTKekalspcvssirptpsfl 604  Japanese medaka
XP_029317698  409 ----------DAKISSMERGMRELEEEVNMLKSNGALSSEEREEEIKQMEVYRSHSKFMKNK------------------ 460  Cottoperca gobio
XP_026010553  579 fcfdpdviwqDTKISSLERNIRDLEDEVQMLKTSGLLHSDERQDELKQVEVYKSHSKFMKTKeqalspcvssirpap-tf 657  eastern happy
XP_018670964  281 ----------EAKISSLERMNREVELELESTKHEADIIMTQHREDVKQLEAVKSHSDFMKNK------------------ 332  vase tunicate
Q811U3        440 -------------IGQVKQELSRKDTELLALQTKLETLTNQFSDsKQHIEVLKESLTAKEQRAAILQTEvdalr--lrle 504  Norway rat
9_pfamImport  270 -------------VGELDSDVQKKETEIVTLQTRLDTLNNQQSD-RQHIDVLKESLAAKDQRASVLQSE----------- 324 
XP_009296283  433 -------------MDQVKQDLSRKDTQLLGLQTKLETLTNQFSDsKQHIEVLKESLTAKEQRAAILQTEvdalr--lrle 497 
Q6PH08        436 -------------IDQLKQELSKKESELLALQTKLETLSNQNSDcKQHIEVLKESLTAKEQRAAILQTEvdalr--lrle 500  house mouse
1_pfamImport  298 -------------IDQLKQELSKKESELLALQTKLETLTNQNSDcKQHIEVLKESLTAKEQRAAILQTEhlvdelnlnye 364 
8_pfamImport  295 -------------IEQLKQELNRKESEMQALQTKLETLTNQNSDcKQHIEVLKESLSAKEQRANTLQTEvdalr--vrle 359 
XP_031143341  456 -------------IDQLKQELSKKESELLALQTKLETLNNQNSDcKQHIEVLKESLTAKEQRAAILQTEvdalr--lrle 520  pikeperch
XP_022538566  441 -------------IDQLKQELSKKESELLALQTKLETLNNQNSDcKQHIEVLKESLTAKEQRSAILQTEvdalr--lrle 505  Mexican tetra
XP_023812415  605 fptqhpwiteqaeIETLKQELNKKESEMQALHTKLETLTNQNSDcKQHIDVLKESLAAKEQRANTLQTEvdalr--vrle 682  Japanese medaka
XP_029317698  461 -------------MEQAKQDLGRKDSELLAFRTKLETLNNQFSDsKQHVDVLKESLTAKEQRAAILQTEvdalr--lrle 525  Cottoperca gobio
XP_026010553  658 lptqqpwiteqaeIEQLKQELNRKESEMQALQTKLETLTNQNSDcKQHIEVLKESLSAKEQRANTLQTEvdalr--vrle 735  eastern happy
XP_018670964  333 -------------VDQLKSDVQKKETEIVTLQTRLDTLNNQQSDnRQHIDVLKESLNAKDQRASVLQSEvdslr--nrld 397  vase tunicate
Q811U3        505 eKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL--QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTN 582  Norway rat
9_pfamImport  325 -KQAVLDEKQDYLLRLQEDKSGDTAELSHLRDTLDVKDRKIMVL--HKKIESLSEVLRDKDRVLDENKRAMAELEQDSCT 401 
XP_009296283  498 eKETTLNKKSKQIQEMSEEKSTLNGEIHDLKDMLDVKERKVNVL--QKKIENLQEQLRDKEKQMSSLRERVKSLQTDTSN 575 
Q6PH08        501 eKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL--QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN 578  house mouse
1_pfamImport  365 rKATFLNNWSEKLRFKTSQCGTLFHAVENLQQMLVIKKRKVGGItkQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN 444 
8_pfamImport  360 eKEQLLTKKTKQLQDLTDEKSTLSGEIRDMKDMLDVKERKVNVL--QKKIENLLEQLKDKDKQLAGLRERVQGLQTDSSN 437 
XP_031143341  521 eKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL--QKKIENLQEQLRDKDKQLGNLKDRVKSLQTDSSN 598  pikeperch
XP_022538566  506 eKESFLNKKSKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL--QKKIENLQEQLRDKDKQLGNLKDRVKSLQTDSTN 583  Mexican tetra
XP_023812415  683 eKEQLLTKKTKQLQDLNDEKSTLTGEIRDMKDMLDVKERKVNVL--QKKIENLLEQLKDKDKQLAGLRERVQGLQTDSNN 760  Japanese medaka
XP_029317698  526 eKESLLAKKSQQISELTEEKSTQQGEISDLKDMLDVKERKVNVL--QKKIENLQDQLRDKEKQLGGLKDRVKSLQTDTSN 603  Cottoperca gobio
XP_026010553  736 eKEQFLTKKTKQLQDLTDEKSTLTGEIRDMKDMLDVKERKINVL--QKKIENLLEQLKDKDKQVAGLRERVQGLQTDSSN 813  eastern happy
XP_018670964  398 eKQRILDEKQDYLLRLQEDKSCDASELSHLRDTLDVKDRKILVL--HKKIESLSEVVRERDGMLEEKKRALVALEEDSCT 475  vase tunicate
Q811U3        583 TDTALTTLEEALADKERTIERLKEQRDRDEREKQEEIDTYKKDLKDLKEKVSLLQGDLSEKEASLLDLKehasSLASSGl 662  Norway rat
9_pfamImport  402 SDSALTTMEEALADKDKVVEALQKEHASSCQQFRDESADLRQCLKNAEQQLDSLRREMSEKESSISELQerasSLASSMv 481 
XP_009296283  576 TDTALTTLEDSLAEKERIIERLKEQRDREEREKAEELDTSKKELKELKEKVSLLQGDLSDRETSLLDLKehasSLASSGl 655 
Q6PH08        579 TDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKehasSLASAGl 658  house mouse
1_pfamImport  445 TDTALATLEEALSEKERIIERLKEQRERDDRERLEEVESYKKENKDLKEKVNALQAELTEKESSLIDLKehasSLASSGl 524 
8_pfamImport  438 TDTALTTLEEALSEKERVIEALREQKDREDRVRLEELEQMRKENQVLKETLSALQPHKLPQSQPANSVLt--qNQRPDGa 515 
XP_031143341  599 TDTALATLEEALSEKERIIERLKDQREREDRERLEEVESYKKDNKDLKEKVNSLQIELTEKESSLIDLKehasSLASSGl 678  pikeperch
XP_022538566  584 TDTALATLEEALSEKERIIERLKEQREREDRERMEELESYKKENKDLKEKVSTLQVELTEKESSLIDLKehasSLASSGl 663  Mexican tetra
XP_023812415  761 TDTALATLEEALSEKERVIENLREQKEREDRARTEELEQMRRENQILKDKLSAQQPIKLSQS----PAPnhtsTQDQRP- 835  Japanese medaka
XP_029317698  604 TDTALGTLEEALAEKERIIERLKEHREREEREKGDEVESSKKELKELREKVSHLQTDLADRETSVLDLKekasSLASSAl 683  Cottoperca gobio
XP_026010553  814 TDTALATLEEALSEKERVIENLREQKDREDRVRLEELEQLRKENHELKDKLSVMHPQKQPQNQLGNPSP----SQNQRP- 888  eastern happy
XP_018670964  476 SDSALTTMEEALADKDKIVEALQHEISLLRQQLRDESADLNQQLKNAEQQLDCSRRDVTERETSISELQeqatSLASSIv 555  vase tunicate
Q811U3        663 kkdsrlktlEIALEQKKE---ECLKmesQLK-------------KAHEATLEA--RASPEMSDRIQQLEREIARYKDESS 724  Norway rat
9_pfamImport  482 kkdshikqlEINVQKSFD---DVTRlqtQHL-------------KAQQLAMSE--TTKEEFNSKIQTLENEVKLKAEEAT 543 
XP_009296283  656 kkdsklkslEIALEQRRE---ECSKlenQLK-------------KAHSAAVNA--QANAEISERISSLEADVSRHREDSA 717 
Q6PH08        659 krdsklkslEIAIEQKKE---ECNKleaQLK-------------KAHNIEDDS--RMNPEFADRLKQLDKEASYYRDECG 720  house mouse
1_pfamImport  525 kkdsklkslEIAIEQKKE---ECSKlesQLQ-------------KAHEAEEAA--RVNPEIVNKVKHLEKEVAYYKEESG 586 
8_pfamImport  516 ki----dslEIEVETKVDkppTGSAtvgSLYfmllc----lwyrKTQNMEETV--RKCPDITDRLRLLEQEVARNKEESG 585 
XP_031143341  679 kkdsklkslEIAIEQKKE---ECSKletQLQkqaeqlfshmnnpKAHEVELQSgpRGNPEYVDRVKLLEKEVSYYKDEAN 755  pikeperch
XP_022538566  664 kkdsklkslEIAMEQKKE---ECSKletQLQk------------KAHEVEVVQgsRGNPDFLDRVKLLEKEVNFFKEESN 728  Mexican tetra
XP_023812415  836 ---------DGEVQVKVD---PAIG-----P-------------TTQNMEDAV--RIGPDIADRLRLLEQEVARYREESS 883  Japanese medaka
XP_029317698  684 kkdnrlksmEISLEQKRE---ECVKlenQLK-------------KAHNSASDS--QASIELSDQISCLEQEVTRHKEDAG 745  Cottoperca gobio
XP_026010553  889 ---------DAEVKTKVD---GPPA---VSP-------------TIQTTEEAV--KMCPDITDRLRVLEQEVGRYREESR 938  eastern happy
XP_018670964  556 kkdsfikqlEINIQKHTE---DFNRlqnQHK-------------KAQQQAMTE--TTKEEFNLKIRNLEIEVQSKVDEAS 617  vase tunicate
Q811U3        725 KAQTEVDRLLEILKEVENEKNDKDKKIAELEslts----rqvKDQNKkv----------aNLKHKEQVE----KKKSA-- 784  Norway rat
9_pfamImport  544 RCQGDLDRLLGILKETENEKHLKDKKIATFEkr--------cKEQAT-------------KIKSMQNEMiqdaQRKGAaq 602 
XP_009296283  718 KAQAEVDRLLDILRQMENEKNDKDRKISELErq--------mKEQSKksgkhkeppgkgrNVNDGPQQEslrqKAERI-- 787 
Q6PH08        721 KAQAEVDRLLEILKEVENEKNDKDKKIAELEsltl----rhmKDQNKkv----------aNLKYNQQLE----KKKNA-- 780  house mouse
1_pfamImport  587 KCQAEVERLLDILREVETEKNDKDKKIAELEsmtl----rqvKDQNKkv----------aNLKHNQQVE----KKKNA-- 646 
8_pfamImport  586 KSQSEVERLMAALRDAEMDKLCKEQKIENLEscillmflrpkKCEPV-------------NLKASQQFK----TRKAA-- 646 
XP_031143341  756 KAQTEVERLLDILREVETEKNDKDKKIAELEslap---rqggKDLTKkg----------pNIKLGPQGD----KK----- 813  pikeperch
XP_022538566  729 KSQAEVERLLEILREVESEKNDKDKKIAELEslap----rpgKEQNKkg----------pNIKLGQPGD----KKGS--- 787  Mexican tetra
XP_023812415  884 KSQAEVERLMGALRDAETEKSSKEKKIADLErpg------qiKSPNI-------------QKQMVPCEM----RK----- 935  Japanese medaka
XP_029317698  746 KAQSEVERLLEILREMENEKNDKEKKINELEslas----rqmKDQSKkv----------aNFKHKEQLE----KSRNA-- 805  Cottoperca gobio
XP_026010553  939 KSQAEVERLMGALKDAEMDKSCKEKKISDLErq--------iKSPNI-------------QKQTVPGEM----RKDALid 993  eastern happy
XP_018670964  618 RCQGDLDRLLGILKETENEKHSKDEKISAMEkk--------hKEQTM-------------KIKSLQTEMieeaRRKGAaq 676  vase tunicate
Q811U3        785 -------------------------QMLEEARRR-------------EDSLSDSSQQLQ--------------------- 805  Norway rat
9_pfamImport  603 drdik--------------skdervEELEEALREsvsitaeremllaKMDEKAKASQQQ--------------------- 647 
XP_009296283  788 -------------------------EELEEALREsvqitaeremvlaQEEAARNHQEKQ--------------------- 821 
Q6PH08        781 -------------------------QLLEEVRRR-------------EDSMVDNSQHLQ--------------------- 801  house mouse
1_pfamImport  647 -------------------------QLLEEGRKR-------------EDNRTDNSQHLQ--------------------- 667 
8_pfamImport  647 -------------------------ALLQLHSRPs------------TDALASDSREKQ--------------------- 668 
XP_031143341  814 -------------------------GLGQDPR---------------KDSSMDSGHHVK--------------------- 832  pikeperch
XP_022538566  788 -------------------------SILQDPR---------------KDNPMDNP---K--------------------- 803  Mexican tetra
XP_023812415  936 -------------------------DVLVDGH---------------------PHSLSQ--------------------- 948  Japanese medaka
XP_029317698  806 -------------------------QLMDDARKR-------------EDNLNECSLQIKdslrqkeerieeleealresv 847  Cottoperca gobio
XP_026010553  994 ghphslsqlpllasqdamrdtaeriMELERALREsmntsahrealwaQEEAARVQAQRQ--------------------- 1052 eastern happy
XP_018670964  677 d---------------------------------------------------rdvAKYLsemqtkderveeleealresv 705  vase tunicate
Q811U3        806 -----------------------VEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEA 862  Norway rat
9_pfamImport  648 -----------------------LSETTEELSKTKSKLDEVGKKLTSVESSLTSKDRILVKMKMERRKQLEERLEMKQEA 704 
XP_009296283  822 -----------------------MEELLGAMEKVKLELESMKAKMSSTQQSLAEKEAHLTTLRAERRRHLEEVLEMKQEA 878 
Q6PH08        802 -----------------------IEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEA 858  house mouse
1_pfamImport  668 -----------------------LEELMNALEKTRQELDATKQRLSSTQQSLAEKEGHLTNLRLDRRKQLEEILEMKQEA 724 
8_pfamImport  669 -----------------------LEELMGALEKTRQELDATKLHLSSTQQSLHERDGHLNSLRHERRKQLEEILEMKQQA 725 
XP_031143341  833 -----------------------LEELMNTLERTRQELDSTKQRLSSTQQSLQERDGHLTNMRQERRKQLEEILEMKQQA 889  pikeperch
XP_022538566  804 -----------------------MEELMNVLEKTRQELDATKQRLTSTQQSLTERDGHLTNLRQERRKQLEEILEMKQQA 860  Mexican tetra
XP_023812415  949 -----------------------LEELMGALEKTRQELDATKLRLSSTQQCLHERDGHLSNLQHERRKQLEEILEMKQQA 1005 Japanese medaka
XP_029317698  848 qitaerevvlaqeeqgrthsekqVEDLLVAMERVKQELDVMKAKLSSTQLSLAEKEGHLTALRAERRKHLEEVLEMKQEA 927  Cottoperca gobio
XP_026010553 1053 -----------------------LEELMGALEKTRQELDATKLRLSSTQQSLHERDGHLNSLRQERRKQLEEILEMKQQA 1109 eastern happy
XP_018670964  706 sitaerevvlagveegrrvaenqLAELVAEFTKTKQVLEETGMRVASMEVMVESKDRMLEKLRGERRKQMEEALEMKQEA 785  vase tunicate
Q811U3        863 LLAAISEKDANIALLELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 914  Norway rat
9_pfamImport  705 LLAAISEKDSNIALLELSQSrKKTNAEEVCLLRREKDSLVQQLKQQTQNRLKL 757 
XP_009296283  879 LLAAISEKDANIALLELSSSkKKKTQEEVAQLRREKDRLVQQLKQQTQNRMKL 931 
Q6PH08        859 LLAAISEKDANIALLELSASkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 911  house mouse
1_pfamImport  725 LLAAISEKDANIALLELSASkKKKTQEEVMALKREKDRLVHQLKQQTQNRMKL 777 
8_pfamImport  726 LLAAISEKDANIALLELSSSkRKKSQEEVMALKREKDKLMHQLKQQTQSRMKL 778 
XP_031143341  890 LLAAISEKDANIALLELSASnKKKTQEEVLALKRERDKLMHQLKQHTQSRMKL 942  pikeperch
XP_022538566  861 LLAAISEKDANIALLELSSSnKKKTQEEVMSLKREKDRLMQQLKQQTqsrmkl 913  Mexican tetra
XP_023812415 1006 LLAAISEKDANIALLELSSSkRKKAQEEVMALKREKDRLMHQLKQQTQSRMKL 1058 Japanese medaka
XP_029317698  928 LLAAISEKDANIALLELSSSkKKKTQDEVAALKREKDGLVHQLKQQTQNRMKL 980  Cottoperca gobio
XP_026010553 1110 LLAAISEKDANIALLELSSSkRKKAQEEVMALKREKDRLMHQLKQQTQSRMKM 1162 eastern happy
XP_018670964  786 LLAAISEKDSNIALLELSQPrKKSNADEVCLLRREKDALVQQLKQQTQNRLKL 838  vase tunicate
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