Conserved Protein Domain Family
FTH

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pfam01827: FTH 
FTH domain
This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.
Statistics
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Structure
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PubMed ReferencesClick to see Conserved Features Help

pfam01827 is the only member of the superfamily cl28746
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O45671  614 DKFIDYIGTVLKSvGHKIPVKSLSIQAYNQSSMMHILPH---LDSRSLRSISIqkpvedknkvpCSWIQPLEIDEICQLE 690  Caenorhabditis elegans
Q9XU20  201 DKFCRLFVGKIEN----ISPTEIYLRFWTCKAVASFLKL---CSADQLKHIDLh----------FHDEELLEYNEFVNLN 263  Caenorhabditis elegans
O76644  110 NRIYKQFRNRSETaEGALFVHSLGLQVENVSQLRSVLPC---FNPNKLKELIIhn--------kTIREKTIDFRDIVETD 178  Caenorhabditis elegans
O17299  110 NRLYEQFKIHSQTtKNPIYVRSLHLQIENLSQLCSVLTY---FNPDKLTELTI-----------AYLGKPFGFKNIVVMD 175  Caenorhabditis elegans
Q9XV32  526 DVFIKYFGDNLKSiGHKIQVKELNMQACNQNTVMHVLPY---LDTRVLRSISIqipvqketkvpCDWIEPLEINEICELE 602  Caenorhabditis elegans
Q9TYQ1  172 NRFLKSFKDLHASlGRLLPVEKLVVTTRNQKTIVQLLQS---VDPSKLNKIEFgts------fdVPASDVWSIEEFLVME 242  Caenorhabditis elegans
O17299  430 EQFVEMFSKSIFLrGDLIPVVELCLRTLSLKVAAQMLQN---VDPVAIKTIEIrppl----gipIALQLESHLEQLVCLE 502  Caenorhabditis elegans
O76644  454 DQFIETLNRTFFScGTLFPVEKFILTTICLKQAALTLQN---VDPVTLKSIELrs--------nSFLNIVQPFDDLASLE 522  Caenorhabditis elegans
O17998  111 ARTLEAIKNTLSSkKPSLKINELVFSFSGQPMFAPAIAItetLDSGPLKSIHLs----------TDKEEEMDCDGLTKLP 180  Caenorhabditis elegans
Q9XVC2  141 VILTEIIRETLMPeETRLKVNTVRLVGIDMKMMTRILSY---LDEKMLNAINLvyd-----aesRNEREELDTGRMVKLA 212  Caenorhabditis elegans
O45671  691 QWKSTKIVDIEHVIDIA-DIKTFGHFSEADVKLASLTMKGILCLKTE-F-LLSED----FVKFKAsfeTSNVDESIYEVS 763  Caenorhabditis elegans
Q9XU20  264 HWKNAKYLKLYCKYLPTrFYQNLSNFKVLSLRPDQSSVEDIDQIKKL-IsEPNQLsamvFQSVAA-------LDTVYIAS 335  Caenorhabditis elegans
O76644  179 HWKNATHIKLEGVSV---PFDNFSHCEDVRIHASKVSANDIQTLVEI-A-YKGSS----LRFFYV---RCDSFDEDVTEQ 246  Caenorhabditis elegans
O17299  176 HWKNAKKIQLDCIVVEI-PIENFSHCEDVTIFVLCISADDIRTLVNA-IvSNSSC----LKHFCF---TYHCLHENITEQ 246  Caenorhabditis elegans
Q9XV32  603 QWKNARMLEIEHVINTT-GMKHLGHFSEADVKLTRMTTEGILCLKAE-F-LLSNN----FEKFKAsfetsdiDESIYETE 675  Caenorhabditis elegans
Q9TYQ1  243 QWRNAKELTIIKRVIKC-DVENLVHFRKVDIILDSLSLKNVIYLRDM-F-LVSPD----FLQFKVtfvnsdvNNSIFQEG 315  Caenorhabditis elegans
O17299  503 QWTSARELKIEHFFVDC-DIENLIHFSKVDIRITSISLKDVLYLKKK-F-LLSSN----FLQFKAkfsktnvdDSIFEDN 575  Caenorhabditis elegans
O76644  523 QCKNADELKMENFRVQC-GLEKLIHFAKVDIGLYSISLEDVLYLKEK-F-LMSSK----FRQFKAafhetdvNNSIFEVN 595  Caenorhabditis elegans
O17998  181 HWKRIKSLLIEGFIVSA-PLEHFLHLPEVTITMQSITIFNLKLLKKHfLgLKSEK------KFVLkykLDDGEIADNVHA 253  Caenorhabditis elegans
Q9XVC2  213 QWKNAKILSVEKCAVSF-PIESIGHFYKVKLCFRQITIQDLLYLKEI-FiNSCVPrkfkIQSRSF--------DAENLDE 282  Caenorhabditis elegans
O45671  764 LLGwPF 769  Caenorhabditis elegans
Q9XU20  336 AFG-HR 340  Caenorhabditis elegans
O76644  247 LLDsLI 252  Caenorhabditis elegans
O17299  247 FLDnLI 252  Caenorhabditis elegans
Q9XV32  676 YLGlPF 681  Caenorhabditis elegans
Q9TYQ1  316 FLGiPF 321  Caenorhabditis elegans
O17299  576 FLGePF 581  Caenorhabditis elegans
O76644  596 FLGaPR 601  Caenorhabditis elegans
O17998  254 VFE-QA 258  Caenorhabditis elegans
Q9XVC2  283 TFGlPF 288  Caenorhabditis elegans
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