2BU3


Conserved Protein Domain Family
Phytochelatin

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pfam05023: Phytochelatin 
Phytochelatin synthase
Phytochelatin synthase is the enzyme responsible for the synthesis of heavy-metal-binding peptides (phytochelatins) from glutathione and related thiols. The crystal structure of a member of this family shows it to possess a papain fold. The enzyme catalyzes the deglycination of a GSH donor molecule. The enzyme contains a catalytic triad of cysteine, histidine and aspartate residues.
Statistics
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PSSM-Id: 461526
Aligned: 63 rows
Threshold Bit Score: 180.436
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BU3_B            36 QTLTLSPNLIGFNSNEGEKLLLTSRSR---EDFFPLSXQFVTQVNQAYCGVASIIXVLNSL--GINa------PETAQYS 104 Anabaena sp.
Q21NE9            77 DDWSLPENMVDLRSEEGQTRLLECsy---cEDYPTLATAYLTQATQTFCGLASTTMVLNA-----DaesrkwrPVTQPYQ 148 Saccharopha...
Q111Z2            31 QRLPLSENLTSLLSPEGQTLLQTSKAQ---TDYIPLMSQFVTQVNGAFCGVASAVMVLNAL--EVP-------STAPSPW 98  Trichodesmi...
jgi:Syn6312_3727  38 qTLTLEAGLTSLTSRTGESLLETSQAK---ADVLPLMSHFVTQINPAYCGVASSVMVLNAL--GVTt------ANTPAW- 105
Q63T30            24 QPLPLPAGLIDLGSLAGEQMLAESGAR---SAYASLGSHFVTQKTQSYCGVASLVMVLNAL--RVPa------PAAAQYP 92  Burkholderi...
EDQ84778          32 REMPLPPELIASNSSAGVQLLLSAQAQgyaEPFWQLSMTYTTQQNQAYCSVASSAMSLNAL--GVPa------PVDAVYS 103
jgi:MICPUN_61050  29 tlLPVPTDDIPLNSTEGERLLRDCTHY----PGVDVLMHLATQRNQAFCSAATAATLLNAMarTVTa------PVDVEFA 98 
Q13MK8            31 GPLPVPPNLVALTQPSGQKRLTGSASN---QSYWPLSQYFETQRNEAYCSVATSVMALNAL--GIRr------PESTQYP 99  Paraburkhol...
jgi:Cyagr_2386    12 aagRLRAAPIPLMQPAGMELLVASGER---ADYGPLAEQFLTQANLAYCGVASAAMVLNSL--AVPa------PPVPGYG 80 
Q7V6X1            36 SNPALAEKLVPITTSEGMVLLQRSKSV---SDYGSLMEAFLTQSNLAYCGVASAVMVLNSL--AIPa------PPVDGFR 104 Prochloroco...
2BU3_B           105 PYRVFTQDNFfSNeKtk--------avIAPEVVARQGXTLDELGRLIASYG-VKVKVNHAs--dTN-------------- 159 Anabaena sp.
Q21NE9           149 PFNFYTQCNLlNDeVre---------hIDVAKVLNEGMELNEIFFVVKNQP-SVVEAYCQhatsaqnkgelpasdaphnc 218 Saccharopha...
Q111Z2            99 PQRYFTQDNIfNe-Kte--------evIPRSVITRRGMTLAQLSDFIATYS-VEVKTFYGs--dIS-------------- 152 Trichodesmi...
jgi:Syn6312_3727 106 QRGYLNQDTIfTp-Qtn--------avIDRHLIAHQGLTLSQLAEFLQTYP-VTVERYYGs--dLG-------------- 159
Q63T30            93 PFHYFTQDNVlGd-Ate--------riRPRALIERHGMTLDQLGALANALG-ASGDVRHAs--dVS-------------- 146 Burkholderi...
EDQ84778         104 PYNYFTQSDVfTPcAvn--------qnITEAYVATHGLTLAQAHALLACFPaVDAQLHHAgqagAD-------------- 161
jgi:MICPUN_61050  99 PYPYFTQRSIlQDaCvrrvpthedgtlMSVKFLATHGATLHEWATYLSCF--AEVEHVHAe--vST-------------- 160
Q13MK8           100 DFPFFSQDDFfRg-Idp--------qvANAAQVSREGMTLDQLGTALQAFP-IDVRKYHAs--dLS-------------- 153 Paraburkhol...
jgi:Cyagr_2386    81 RYRFWTQENVfDVpAgs--------qvVSAEVVRRQGMTLTELAGLLAAHG-VKADAIHGd--rLS-------------- 135
Q7V6X1           105 NYHFWTQDNIfNSdSsq--------vvISPAKIRRQGMTLQELQNLLSHHG-VSSKRLHGd--iLS-------------- 159 Prochloroco...
2BU3_B           160 -----IEDFRKQVAENLKQDg-----NFVIVNYLRKEIGQERGGHISPLAAYNEQTDRFLIXDVSRYKYPPVWVKTTDLW 229 Anabaena sp.
Q21NE9           219 gvdqdyntFMKTITNALNTPr-----HYVIANFAGAPSPERG-GHFSPIAAYHKASDSFLIMDVARYKYPPFWISSKELW 292 Saccharopha...
Q111Z2           153 -----LEQFRGLIRENLVNDn-----NFVLINYLGQAIGQKRGGHISPIAAYNEESDQFLVLDVSRYKYPPVWVDTKTLW 222 Trichodesmi...
jgi:Syn6312_3727 160 -----LAEFRQILGISLGKAn-----QYILVNYLRSSIGQETGGHISPLAAYHAEQDQVLILDVARYKYPPIWVSVQALW 229
Q63T30           147 -----VDVFRADAIAHLGRPg-----RYVLVNYLRSRLGQQTGGHISPLGAYDAAADRFLILDVSRYKYPPVWVTTADLY 216 Burkholderi...
EDQ84778         162 -----LAAFSRDLNATSQGTh-----ALIIINFLRTGMHQEGGGHFSPLAAYDPVSDRILVLDVARYKYPSFWATRQDVF 231
jgi:MICPUN_61050 161 -----AAAFRDVVKAVFPTTrgakaeKFVGINFLRTGVGEDGGGHMSPIAAYDETADRVLIADVSRYKYPPVWARLTSVY 235
Q13MK8           154 -----LHQFRDLVRTTTGHDd-----RFVLLNFRRIEIGETGGGHWSPLAAYDATSDSALLLDVARYKYPAVWVPVAQLY 223 Paraburkhol...
jgi:Cyagr_2386   136 -----LEQFRALLRANLSQPg-----DRLLANYLRPSLGQAGGGHIAPLAAFHAPSDRVLILDVARYRYPSVWVPVADLW 205
Q7V6X1           160 -----LQAFRSLIKANLDDSs-----DRLIVNYDRKVIGQKGGGHFSPLAAYDAVTDKVLILDVARYRYPSVWVKTHDLW 229 Prochloroco...
2BU3_B           230 KAXNTVDSVS-QKTRGF 245 Anabaena sp.
Q21NE9           293 QAMQKIDSGS-GKARGY 308 Saccharophagus degradans 2-40
Q111Z2           223 ASTNTIDKTS-KKTRGI 238 Trichodesmium erythraeum IMS101
jgi:Syn6312_3727 230 QAMGTIDPVS-GKSRGF 245
Q63T30           217 AAMNTPDADSgGRSRGY 233 Burkholderia pseudomallei
EDQ84778         232 NAMNTIDSSS-QQTRGW 247
jgi:MICPUN_61050 236 GAMNTTDDAS-GKSRGW 251
Q13MK8           224 AAALAVDSVS-GLSRGI 239 Paraburkholderia xenovorans LB400
jgi:Cyagr_2386   206 AAIRTIDSTS-GRSRGL 221
Q7V6X1           230 RAMRTLDGIS-GLQRGI 245 Prochlorococcus marinus str. MIT 9313
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