5J1L,5J1L,4ZYB,5KQB,6SMK,2GU1,6UE4,4BH5,3TUF,5B0H,4RNZ


Conserved Protein Domain Family
Peptidase_M23
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pfam01551: Peptidase_M23 
Peptidase family M23
Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins such as Swiss:P33648 for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.
Links
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Statistics
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PSSM-Id: 460250
Aligned: 234 rows
Threshold Bit Score: 42.1481
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5J1L_A  64 NHTGLDLSTAiNT--------PVYASASGVVglASKGW---NG-----GY-GNLIKVFH---PFG-FKTYYAHLNKIV-- 120 Helicobacter pylori 2...
O69910  86 GHRGVDLAAGgGA--------PVRAVAAGRV--SFAGP----------VGgRGVVSVELtgtGEPpLRTTFAP---VDaa 142 Streptomyces coelicolor
Q82JX6 108 GHRGVDLAAApGT--------PVRSVAAGRV--SFAGR----------VAgRGVVSVELtgtGEPpLRTTYEP---VRps 164 Streptomyces avermitilis
Q8FP69  82 GHRGVDLPLAiGA--------DVLSAGDGVV--VFAGM----------VAgTPTISIDH---ADG-VRTTYQPVHAh--- 134 Corynebacterium effic...
Q8NP00  62 GHRGVDLPLNiGE--------TVLASGSGTV--AFAGI----------VVgTPTISIDH---ADG-VRTTYQPVHAh--- 114 Corynebacterium gluta...
Q21241  58 IIDGVDVRCHlGE--------PIYAPIEGEM--YFWRP---YGgkrekSCaDQGVRIEG---TGQ-WQGYAVHISSVK-- 118 Caenorhabditis elegans
5B0H_B  36 PHQGVDVLCSaGS--------TVYAPFTGMI--VGQEKpyqNK-----NAiNNGVRIS----GRG-FCVKMFYIKP---- 91  human
P08940  66 KHKGVDVICTdGS--------IVYAPFSGQLsgPIRFFhn-------gNAiDDGVQIS----GSG-YCVKLVCIHP---- 121 chicken
P9WKW9 275 FHPGVDFATDpGT--------PVYAVASGAV--SAIDE---VD-----GL-VSLTIARC---ELD-VVYVFRPGDEGR-- 329 Mycobacterium tubercu...
Q8PD91 248 PHGGTDFNYEgGQqgrnlqhpTVHSPVSGTV--TFAGG----------NY-GTVKIHDA---QGN--SHEILHLDALK-- 307 Xanthomonas campestri...

5J1L_A 121 VK-TGEFVKKGQLIGYSG-NTGm---ST-------GPHLHYev-rfLDQPINP 160 Helicobacter pylori 26695
O69910 143 VR-KGDEVAAGEPLGTVQ-PTGsh-cTA---------CLHWgl-lrGEVYLNP 182 Streptomyces coelicolor
Q82JX6 165 VE-KGDEVAAGGSLGTLE-PTTahcsTA---------CLHWgl-lrGRTYLNP 205 Streptomyces avermitilis
Q8FP69 135 VS-AGDPVVAKQAIGTLGhPT-----TA-------YPGLQWga-riGDDYINP 173 Corynebacterium efficiens
Q8NP00 115 VS-VGEHVEEGDAIGILGhPT-----TK-------FPGLQWga-kiGEEYINP 153 Corynebacterium glutamicum
Q21241 119 LSfFGGHVEAGDEIGEAL-NRYc---FNdrgqndvEPHVEIrl-ykEGRLIDP 166 Caenorhabditis elegans
5B0H_B  92 IK-YKGPIKKGEKLGTLL-PLQk---VYpg----iQSHVHIe----NCDSSDP 131 human
P08940 122 IR-YHGQIQKGQQLGRMLpMQK----VFpg----iVSHIHVe----NCDQSDP 161 chicken
P9WKW9 330 LV-LGDRIAAGAQLGTIG-AQGe---SA-------DGYLHFev-rtQDGHVNP 369 Mycobacterium tuberculosis H37Rv
Q8PD91 308 VK-EGQTLSAGDAIGTMG-GLGp--nGNsq----yAQHVHYqlrdaNGKLTSP 352 Xanthomonas campestris pv. campestris
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