Conserved Protein Domain Family
Ly-6_related

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pfam06579: Ly-6_related 
Caenorhabditis elegans ly-6-related protein
This family consists of several Caenorhabditis elegans specific ly-6-related HOT and ODR proteins. These proteins are involved in the olfactory system. Odr-2 mutants are known to be defective in the ability to chemotax to odorants that are recognized by the two AWC olfactory neurons. Odr-2 encodes a membrane-associated protein related to the Ly-6 superfamily of GPI-linked signaling proteins.
Statistics
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PSSM-Id: 399524
Aligned: 14 rows
Threshold Bit Score: 127.458
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KRZ83429      42 CASYELRAYW-YH--LQAWYNTPKNFTDRCVTMNRRdcQHIALESCP--SQCITLRQQKTIAGHTVGYH---VIRGCLTS 113
EFO24039      35 CMSPLYEELF-KDgvMSRYFYEPRNFTSQCNEPMRP--SNIGLVACK--SICLTLTQDFVVMGRNTGKKl--TIRGCAVS 107
PDM61878      86 CMSTYYEQLF-NGr-VQNIFNEPKNFTRHCDDPAAP--HLLEAVACR--TICLTITHDLVVFGQRTGQIv--TMRGCAIS 157
Q8T3D0        43 CASFVYLPLW-SQ--LMHHYYPPKNFTDRCWQPD----SGIGLVPCS--SACFTLVER--IDDVSEQHG---VIRGCMDR 108 Caenorhabditis ...
EGT34036      30 CMSKLYEAVW-PS--LSHIYKKPRNFTDDCDDERISe-GRVPIVHCP--TICVSLFEQPNIAGVRIKG----YIRGCMSD 99 
NP_001256848  51 CMSLSYQTSW-KY--LQTTYIYPKVFTDRCRDPNSE--RGMPTVMCG--SVCVSLMEPDVEAGVFIGFK---HIRGCLDR 120
CDK13497      37 CMSKYYGALW-RFagYTRIYQEPGLFTDSCRDPQARg-SDVPSTICKekTNCVTMVEDLKIGTGAKG-----YIRGCWGS 109
CCD83391      30 CMSPYLEDHY-PY--ISHLYRKPLSFDTHCDKHSLEt-SYLYSKNCS--DMCVTLRINDVVGGRRRHG----YMRGCLSD 99 
CRZ25903      39 CMSEAFQKHW-SF--LSQIYFMPMNFTDYCYDMPPK--VHIGVTTCSh-SLCVTVIEPRILAGHHIGNN---VIRGCFSS 109
EGT48406      26 cASFEYRVLFdKDtsLSRKVRVPK-FDRLCDLEEMVq-GFAPVETCH--STCVTIFEPQYFGGLQSLQRpflYIRGCADH 101
KRZ83429     114 LFRWNILdtsQISASLMKPRDFCYNLRLS--QILPSYgsgvkGESDQlVRLCVCHGDRCNS 172
EFO24039     108 ISRHGFF---NRTMVLFDRYDMCRDVKAS--DLFRYE-----SDSQT-IRVCSCFGDRCNV 157
PDM61878     158 IAKKGIH---NHTLAMFDRYDICREMNAA--DLFRTEyg--rGESQR-IKVCSCLGDRcnh 210
Q8T3D0       109 LLLFGLDddvRNILSAYENQRVCRHTDRKllRLFPLSgq-------tdVTFCSCNGDFCNe 162 Caenorhabditis elegans
EGT34036     100 VLISGFNqtiVTWYRWMHRDS-CRPYRKK--ELFKLGge--sTDDST-IDVCTCYADHCNG 154
NP_001256848 121 VLRHGFNqsaLRTHR-FHQNNHCRTLSRS--ALFNPArqtdpPALGD-VQLCSCYGDRCNS 177
CDK13497     110 VFLFGFNr--TGTVGALAEHSFCHTFNLT--QLVSgg----rPEESS-INVCSCRGPLCNG 161
CCD83391     100 L--HGYN---HSLIRTLAERQGCLDTTAR--ELFLPTaqrqeLEPSR-LSLCACHNNLCNF 152
CRZ25903     110 VFKYGPT---PSNDGFSTSDTSCSRMPAY--KLLPPHla-rrASNRT-VELCWCFGQLCNd 163
EGT48406     102 IFSEMKNr--PIEVEFLHRSPICVKLQLS--QIYPq------VQANEiVQVCSCDKDGCNF 152
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