Conserved Protein Domain Family
DUF4656

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pfam15551: DUF4656 
Domain of unknown function (DUF4656)
This family of proteins is found in eukaryotes. Proteins in this family are typically between 286 and 398 amino acids in length.
Statistics
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PSSM-Id: 464761
Aligned: 6 rows
Threshold Bit Score: 485.15
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001504096  34 SQPPPSRRTRRPDPKDPGHHGPESLTFISGSAEPAAEPPAC--CLLwRPWVWDWCRAAFCfrhcrgCLQRCGACVRGCSP 111
XP_002191903  55 AQQMRDRKGRKAELKDPNGREAETITFISGTAEAPPNQSFC--CSS-LSQAWNTYKAVFC------CIVTCGGCFQDCSV 125
XP_003227503  52 RKTPRDRRNRKADPKDPNGREGETITFISGPADPP--QSAC--CPS-FSQAWSAYKAIFC------CIVTCGGCFRDCKP 120
XP_001370576  54 GQPATPRWVRRPNPKDPGARESESITFISGSAEAPPDATAC--CLP-RPWVWNLCKAVFCfrrcraCYQRCGGCVRSCEA 130
XP_014341043  58 AQNAQAKNSRKADPKDSNGRGSETIGFIPGSAESPQESSAC--CQS-GLFVWGMCKAVFC------CVLTCGKYRPEPGT 128 coelacanth
XP_015204320  60 TRRPPPQQTRKAHPRDANGRESETIGFIPGSADNPPSTQTCgsCSS---LGWSSCRALIC------CIFSCGFYKTEPSV 130 spotted gar
XP_001504096 112 CLSAGDSPEGAAEASWAKE----HNGVPP--SPDHAPPSRRDGQ----RLKTTMGSSFSYPDVKLKGIPVYRYRpATSPA 181
XP_002191903 126 CIPYPGPAETSTEDGKNGD----YNGRLPn-SPTNTSPAEKNGNq---IKKSSMGSSFSYPDVKLKGIPVYPNR-NTNHH 196
XP_003227503 121 KIPYP-YIETLTEDVKGQE----CNGRSPt-SPTSGSPAEKNGNp---TKKSTVGSSFSYTDIKLKGVPVFPNR-SPSSH 190
XP_001370576 131 CLPSLGPPESFPEEGWSKE----HNGGPPpnSPAVAPPSRRVGE----RLKPTTGSSFSYPDVKLKGIPVYRYRgGLAPS 202
XP_014341043 129 CICV--TSSDAPTDVKPYE----PNGHIS--MPVSNSPCDAQSNhsgkKKAPINGNSFNYPDLKLKGVPVYS---SNSSS 197 coelacanth
XP_015204320 131 YIPCLDRNETSTEDVKSSQepkrPNGLALs-NPTSGISLETKHS------KPPLSDSFNYPDIKFKGERVKL-------- 195 spotted gar
XP_001504096 182 PDVDSCCKEPLAEpPPMRHSLPSTLASSPRGSEEYYSFHESD-LDLPEIgSGSMSSREIDVLIFKKLTELFSVHQIDELA 260
XP_002191903 197 PESDSCCKELLEK-PFRNSIEKPPLPSSHRSSEEYYSFHESD-VDISEL-NGSMSSRQIDVLIFKKLTELFSVHQIDELA 273
XP_003227503 191 TDTDSCYKEPLPE-KISWPSQKQHPPSSHRSSEEHYSFHESD-FEFGEL-NSSMSSREIDVLIFRKLTELFSVHQIDELA 267
XP_001370576 203 SDADSCYKEPPAE-PPLRYSLPGTLGGSPRSSEEYYSFHESD-LDLPELsGGSMSSREIDVLIFKKLTELFSMHQIDELA 280
XP_014341043 198 HDPGSCHKEPMPKnKKRNSIEKPPYSNSHRSSDPLSSFLDDDaLFYPTDpESSISSAQIDDLIARKLIKDFTTQQIEELA 277 coelacanth
XP_015204320 196 --------EGRVNaPKRTPSSKSVQKGDTLRPSSSYSLEDPD----QYLdDLSDCSTDIDSLITKKLLELYKLHQIDQLA 263 spotted gar
XP_001504096 261 KCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKS-RT------------RPQ-------T----- 315
XP_002191903 274 KCTSDTVFLEKTNKISDLINSITQDYNLDEQDAECRLVRGIIRISTRKS-RV------------RPHipl-psqS----- 334
XP_003227503 268 KCTSDTVFLEKTNKISDLINSITQDYHLDEQDAECRLVRGIIRISTRKS-RV------------RPRvciptlpS----- 329
XP_001370576 281 KCTSDTVFLEKTNKISDLISSITQDYHLDEQDAECRLVRGIIRISTRKS-RS------------RPAp-----gT----- 337
XP_014341043 278 KCTSDTVFLQKTNQISELINSITQDYNLNEQDAECRLVRGIIRISTRKA-KSkhpksdsaynsiSPTq------N----- 345 coelacanth
XP_015204320 264 KCTSDSVFFRKTSEITELINNIAQDYNLDEQDAECRLVHGVIRISTRKSkRA------------APQksdsaysSgshsr 331 spotted gar
XP_001504096 316 -----TEGRSTRaaasaAAAPDSGHETMVGSGL-SQD-ELTVQISQETTADAIARKLR--PYGAPGY----PTSHDSSFQ 382
XP_002191903 335 -----HEEKSGR-----GNAPDSGNETMLESMViSQD-ELAVQISEETPADVLARNMR--RHSSAGS----PTSRDSSFQ 397
XP_003227503 330 -----QEENSTR-----GNPPDSGNETMVASVLtSEE-DLSVKISVETTADVKARYMRhgPYSVTGS----PLSRGSSYQ 394
XP_001370576 338 -----CESRLSR-----GPAPDSGTDTMLASVL-SQE-DMNVQISQETTSDAIARRLR--PYGTSGY----PPSHDSSFQ 399
XP_014341043 346 -----LDEKLRQlt--kGYPPDSGNETMPDSFIiSQD-DLKVEISEETTSDVIARNLR--PGSAPGTlip---------- 405 coelacanth
XP_015204320 332 epghrAEDRGRRd----GTLPDSGNDTLIETSLtSQetDLDVKISEQTSSDKLARQMR--HSSSQGYssncPTGNYASFP 405 spotted gar
XP_001504096 383 GTDTDSSGAPLLQVYC 398
XP_002191903 398 DTETDSSGAPLLQVYC 413
XP_003227503 395 DTETDSSGAPLLKAYC 410
XP_001370576 400 GTETDSSGAPLLQVYC 415
XP_014341043     ----------------     coelacanth
XP_015204320 406 DAETNSSGTPLLDKYF 421 spotted gar
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