Conserved Protein Domain Family
TRIF-NTD
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pfam17798: TRIF-NTD 
TRIF N-terminal domain
The N-terminal domain of TRIF/TICAM-1 has a structure that consists of eight antiparallel helices. This domain believed to be involved in self-regulation of TRIF by interacting with its TIR domain.
Links
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Statistics
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PSSM-Id: 436052
Aligned: 5 rows
Threshold Bit Score: 198.506
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_008120431   4 SPGLHPSLEGIFHILAQVPEEKLIDYKHKLSCERQNRRSSQLLQTMILLTLKRETEARRSLDALRGDPVAARISRYCTAt 83 
XP_007488996   1 MAELIPSFRGVFDILSQAGQDKLLYLKHKLKTSRPGTKAKDLLYAMILLTLGQETEARICLDSLKGDKASLSVVRTWEG- 79 
ELK19420       1 MACTGPSLSGAFDLLDAAGQDKLLSLQRKLKALRPGCRGADLLHAMVLLTLGQEAAARVSLEALRADAAARLVAHQWAGm 80 
XP_007567988   6 LENQGTGLRAVFDILEKAPSERLLSLTIHL----GESPEDTIIHALCLIILQREAQALRKLQKLEDNPLANHLAEKWHSg 81 
Q1LUQ2         9 SEGGCPNLGKVFEILSQAPQERLFSLTYKM----GRKPTEELVHAMCLIFLKKHEAAHAKLTAIKDSRVGNYLAEMIKT- 83  zebrafish

XP_008120431  84 -ANTANVVPPLQK-EEGAAEMWLAVARIYSLLVDAKWCCHVLRDEAYRVAVAAFRSGGGSKdr-lRGLADEALEKCGMGF 160
XP_007488996  80 -GEPLLNQADHLA-SEDQADIQLTVARIYQLLLEENLCEASSRNKAYKAALQAFRLGQDAQ----LDIMAEAQDLCGHDI 153
ELK19420      81 dSSAEA--------PEEPPDVSWAVAQVYHLLAEERLCPAPMRDVAYQAALRAFGSSDDPRl---GELQEEARNRCGGHI 149
XP_007567988  82 gGKLDDFGAHCSLfEAKTGESLSSLARVFKILSEQRLCDPRLRDLAYKRAISC--KCLNTSsleyDNFREEARAVCGPQF 159
Q1LUQ2        84 -HGERLNCSHIGGfMQTDVNSLLDIARIFAILVQESLCDKSHRDKAYCKAVES----CKTAgllsLDIEEEVKQVCGPDV 158 zebrafish
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