7KID,3UA4


Conserved Protein Domain Family
PRMT5_C

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pfam17286: PRMT5_C 
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PRMT5 oligomerization domain
Statistics
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PSSM-Id: 435841
Aligned: 30 rows
Threshold Bit Score: 197.484
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7KID_A       475 EYTSFLAPISSSKLYNEVRAcrekdrdpeaqfEMPYVVRLHNFHQLSA-----------------PQPCFTFSHPNRDPM 537 human
A0BU75       428 DSVSYCVPVSCPQLHAKVKKsy--------gyDSSYVVHYQKYYTIHD-----------------IQKCMQFKHPDFNNE 482 Paramecium tetr...
Q6CT32       475 GYSSYASPISSPILYQSLIEkgp------eylEKPSIIHNVPYCRTSSr----------------VNEIWSFSHLHQQQH 532 Kluyveromyces l...
P38274       496 SYSSYIAPISSPLFYQKLSQtnr-------slEAPWIVHRVPYCILSSr----------------VNEVWRFEHPMAQKD 552 Saccharomyces c...
XP_001644616 486 SYSSYIAPVSVPLLRQKLKIeng-------dyEKPWILHNIPYCILSSk----------------INEAWKFRHPNEEMA 542
Q75DB6       452 SYTSYVAPVSAPLLYQMLRNked------nalESPWVVRNVPSCLLSTk----------------VYELWSFKHPGGTSN 509 Eremothecium go...
CAK48697     484 SYTAHLTPIAAPKLHADVMNqsisn---paapETPYVVMLHAIDFLSTnqpsaaalmnskapipfVQTTWSFEHPNQHIP 560
EDN99518     591 SYTAHLTPILAPRLHADISNrfssd---esasNTPYVVMFHAIDFLAVsvpg----------hpqIQQAWEFSHPLPVNT 657
XP_011393468 575 SYTAHLSPIAHPRIFADLSNrvvsd---pnafDIPWVTRLFQLAYVAQkvpk----------hgrFQQAWEFVHPVEVSR 641
Q2GP24       565 SYTAHLSPISTPRLFADISSrvsgd---pnafETPWVVRLFAFDFVAQkvpd----------hprFQQAWEFVHPVDILR 631 Chaetomium glob...
7KID_A       538 i-----------------------------DNNRYCTLEFPVEVNTVLHGFAGYFETVLYQ----D-------ITLSIRP 577 human
A0BU75       483 n-----------------------------QLAQEQNLVFECKQDLLIHGMAGYFTSKLYE----D-------IELSTHP 522 Paramecium tetr...
Q6CT32       533 ------------------------------QFNKSSISHFRVKHKSEIHGIAGYFIATLYG----D-------ITLSIVP 571 Kluyveromyces l...
P38274       553 tvqde--------------------ddftvEFSQSSLNEFKIKHRGEIHGFIGFFSANLYN----N-------IFLSTLP 601 Saccharomyces c...
XP_001644616 543 ------------------------------LFSKNITSEFKIKHKGEIDGLIGFFTAKLYG----D-------VTLSTLP 581
Q75DB6       510 -------------------------------TARSTVTNMKIKHKGEVHGLLGFFTAEIYG----D-------IRLSILP 547 Eremothecium go...
CAK48697     561 pqlptt------------------stisnsHNVRRTRLSFPVYNRGVCHGLAGYFETVLYR----D-------IELSTNP 611
EDN99518     658 lhiaearrgggvsg--ggggsmsggdganeHNTRYARLKFVCKDRGVVNGLAGYFEAMLYE----GggnpdnkVELSTRP 731
XP_011393468 642 addfsaqngrarkyvthgsgsmygssgineHNARHCHLTFVCPTRGVIHGLAGYFESVLYKhq-eEgk---tpVEISILP 717
Q2GP24       632 adefaavhgkaakyvtggvgsmsgtsgtneHNARHCHLTFVCPTRGVIHGLAGFFESVLYAsqtgEgk---epVEISILP 708 Chaetomium glob...
7KID_A       578 ET---------------------------------------------HSPGMFSWFPILFPIKQPITVREGQTICVRFWR 612 human
A0BU75       523 NN---------------------------------------------STPDMYSWFPIYFPFEKPVNIAKKQKLKFTIKR 557 Paramecium tetr...
Q6CT32       572 NDsviktledqensnid----------------nsrshngstatkvnHTENMKSWSPMFFPLKEPLFLNDDTELEVFITR 635 Kluyveromyces l...
P38274       602 NDstvrlkfseetlm-------------------ntrreenlikkcdHTPNMTSWSPIIFPLKQPISFIDDSELSVLMSR 662 Saccharomyces c...
XP_001644616 582 DKsmirllpesvnnddfettqnlltgtnsrhhdqtfnsvgiftkkghGTKNLKSWSPIFFPLKNALSVTDDNELSVFLSR 661
Q75DB6       548 DDckiklrgsapdsd-------------------grrksvdldsklgHTPNMSSWSPIFFPLLYPMFVGDDTELELTMLR 608 Eremothecium go...
CAK48697     612 VTmd------------------------------------------tKSADMISWFPIYFPLKTPLNVPDNGEVVVTMYR 649
EDN99518     732 DTid------------------------------------------aKSKDMISWFPIFFPLKSPLYIPDDSELEVSMWR 769
XP_011393468 718 DQid------------------------------------------rKSKDMISWFPIFFPLRQPLYFPQDTELEVSMWR 755
Q2GP24       709 DQid------------------------------------------rKSRDMISWFPIFFPLKKPLYFPQDTELEVSMWR 746 Chaetomium glob...
7KID_A       613 CSN--SKKVWYEWAVTAPVC------------------------------------------------------------ 630 human
A0BU75       558 VNN--EEGVWYEWFNSVLSEddql-------------------------------------------------------- 579 Paramecium tetr...
Q6CT32       636 NDL--NSRVWYEWSVSSFVYlvssseipksegervprtgskenadidtqnltkafarfgpqndsseiedkyfeds----- 708 Kluyveromyces l...
P38274       663 IHSdtEQKVWYEWSLESFIYlmlsnytsavtaasmtiprsivtddtktlahnrhysattnqkldnqidldqdieneeeqg 742 Saccharomyces c...
XP_001644616 662 MSCneMSKVWYEWSMESFVYfvlpssvaaetslykndtttnpnnnttttttpnnnttsntisngksnrglmstnnyssas 741
Q75DB6       609 NRC--MRGVWYEWSLSSYVYnaisqdrkpgsflkgtqqllnskpepnfkdtftrskkhdglnsvmldlqntatilnagdl 686 Eremothecium go...
CAK48697     650 QTD--DRKVWYEWMVEVFAVegneeevvmsggkgtspaag---------------------------------------- 687
EDN99518     770 QTD--DRKVWYEWLVEAFVMvgpnkr------------------------------------------------------ 793
XP_011393468 756 QTD--DTRVWYEWMVEVYAWvgpktr------------------------------------------------------ 779
Q2GP24       747 QTD--DTKVWYEWLVEVYAWvgpntr------------------------------------------------------ 770 Chaetomium glob...
7KID_A           --------------------------------------------------------------------------------     human
A0BU75           --------------------------------------------------------------------------------     Paramecium tetr...
Q6CT32       709 ------------------------------------------------inhtnfmsgrtnewdsvkdlheiqnrhdssnl 740 Kluyveromyces l...
P38274       743 flsnl---------------------------------etgwqsvqdihglsetakpdhldsinkpmfdlkstkalepsn 789 Saccharomyces c...
XP_001644616 742 gggvsksiehesvrnietikssnnnnnsnnnnnssssannntnfdnavlrenefamdqgtawesvkdihgltnteerapl 821
Q75DB6       687 gepreaqydgnie-----------------ensastellkrtfvgksefispeltgwqsvhdvhelgqtmtekpnkgdyn 749 Eremothecium go...
CAK48697         --------------------------------------------------------------------------------    
EDN99518         --------------------------------------------------------------------------------    
XP_011393468     --------------------------------------------------------------------------------    
Q2GP24           --------------------------------------------------------------------------------     Chaetomium glob...
7KID_A       631 -----------------------SAIHNPTGRSYTI 643 human
A0BU75       580 --------------------ldgSRIHNENGKKQII 595 Paramecium tetraurelia
Q6CT32       741 tkdqeqrkkslteeyhvrvrtniSKLHNPNGCIYSI 776 Kluyveromyces lactis
P38274       790 elprhedleedvpevhvrvktsvSTLHNVCGRAFSL 825 Saccharomyces cerevisiae S288C
XP_001644616 822 fnldgpedvdvppeihlrvktgsSALHNVGGCQYSI 857
Q75DB6       750 nseyedkdysnyeeyhvrvrtntTELHNIGGHAYMI 785 Eremothecium gossypii
CAK48697     688 ----nlqrqpqrsrggrrvrvgtSELHSSIKEGCLM 719
EDN99518     794 ------------------lrvgmSEVGSSRQIGCLM 811
XP_011393468 780 ------------------ikvgaSEMHSSRKVACIF 797
Q2GP24       771 ------------------ikvgtSDLHSSRKVACLM 788 Chaetomium globosum CBS 148.51
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