Conserved Protein Domain Family
Dzip-like_N

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pfam13815: Dzip-like_N 
Iguana/Dzip1-like DAZ-interacting protein N-terminal
The DAZ gene-product - Deleted in Azoospermia - and a closely related sequence are required early in germ-cell development in order to maintain germ-cell populations. This family is the N-terminal region that is the only part of the protein in some fungi and lower metazoa.
Statistics
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PSSM-Id: 433498
Aligned: 11 rows
Threshold Bit Score: 152.09
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002603348   1 FQFRKRFERVDWRKIASVDVDRISRELDFHSLQDNIMNITFCDIQQEVCPKpkglMVDPTFVKLFRLAQLTIEYLLHSQD 80  
EAY11966      25 FRWCPRKMPMNWNLIQEVDVDAIVKNMDIDSLEYLVQHIAFANLNNSDAQR----FGSTETLKAFKLLQLGVEYLTHLKR 100 
EEY68722     143 FAFRQRAGKLDTRAIARLDLEKIAASTDIETIQRHLENLAFSDVTLDDVQH----YSDAYFLKLFQIAQLTLEYLMHVQD 218 
CAM37512       6 FQFVQGNERLDWGILVSIDVERLMKSTNVGTLQRIIENIAFSRVTRDEAAL----LTPDHILHLFQLCQVVIQYLVYSQE 81  
Q4DIL5         6 FEFVQGSERLDWGVLVAIDLQRLMKDTNVDTLQRIVENIAFARVTRDEAAM----FTPEHILHLFTLCQLVIQYLVCSQE 81   Trypanosoma cruzi
Q57UR3         6 FQFVQGSERLDWGVLVSIDIQRLIKDTNVDTLQRVVENIAFARLTRDEAAM----FTPDHFIHLYTLCQLVIQYLVCSQE 81   Trypanosoma br...
EGV98751      24 FKFQPRRESIDWRRISAVDVDRVARELDVATLQENIAGVTFCNLDREVCNHcr-qPVDPVLLKVLRLAQLIIEYLLHCQD 102 
AAH91462      30 FRFRSRTEPIDWRRLSTLDVDRVARDMDVSVLQDFIMTVTFCALEGERCPNcr-gPVDPSLVKLLRMSQLSTEYLLQCQD 108 
AAI20216      59 FQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHcq-sGVDPVLLKLIRLAQLTIEYLLHSQE 137 
EDO32713      13 FSFGPRSQPVDWRKLASVDMDRLVRDMDMKMLQDNILHITYCNLETEMGMQs--mQFGPHFLKLFRLAQLIIEYLLHCQE 90  
EEC03346      22 FQFHSRCQKIDWRKIASVDVDKVAREVDVDSLQKNVVHLTFCDIDNELGGA----LVDPNFLKLFKLAQLCMEYLM---E 94  
XP_002603348  81 YLTNI--VGSHDEKLRKANEVRLRTLQEMGKLKeeLQKVKQESR 122 
EAY11966     101 PLPTQpdSSDLRKALSDAQMRIEELENLLYQSE--LKREKAESS 142 
EEY68722     219 SLVDH--SEGLEKQCEQLLTECQELETENGQHEteIASLKREIR 260 
CAM37512      82 ILANI--NVKLNDRMEGQQATAHEREMLLQRLSdeTALLKKQAK 123 
Q4DIL5        82 CLAKI--NVKLTERLQEMQHRRDSAEAEREKLHeeNVILRKEVK 123  Trypanosoma cruzi
Q57UR3        82 CLAKI--NVKLNERMQESQQGVDSLKQECDRLNqeNSVLRKEVK 123  Trypanosoma brucei
EGV98751     103 CLSAS--VAQLEARLQASLGQQQRGQQELGRQAdeLKGVREESR 144 
AAH91462     109 FLSTQ--LAELEERLQAATSLVQQGEGQRAELEksLQETKQENR 150 
AAI20216     138 FLTSQ--LHGLEERLRRSLAEGEHSKKLLTKQAgeIKLLKEECK 179 
EDO32713      91 CLQTS--LEIEMTKVQETMQSAEQVRKELDHKSelHSKQKKEIK 132 
EEC03346      95 LLLQS--LSDVENQVAGTSRLLEEERKFRLCDQeaIRQLQRENR 136 
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