Conserved Protein Domain Family
M_domain

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pfam12938: M_domain 
M domain of GW182
Statistics
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PSSM-Id: 432890
Aligned: 10 rows
Threshold Bit Score: 122.344
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ETN62199             781 DSGPFAGgppRIPPLNhAGGGLSFSQNnqamlnniaigPGASLGSLDGAAGGPA--NLAALNS------FKYLSQgsaaG 852 
ETN64115             738 ASGGVSG---RFAAAAaGIGPMAFQNN-----------QNNLGGGVFSGGNGPAagSSGSFNS------MKFGGN----G 793 
XP_001854407         710 FEPPFSGg--RFP-GGgNGPSLPFPQNpngpn--nnnmPGGMGGG--GGGGGNP--NLAGLNSlskanlQSYLNQ----A 776 
XP_005164151        1140 KDAGLADdaqTSPFM--PSPSLKLPMG-----------SAALPGQSLG-----V--AMQNLNN-------RQMQS----- 1187
PNJ88195             215 KDGGLVEeptPSPFL--PSPSLKLPLS-----------HSALPSQALGGIASGL--GMQNLNS------SRQIPS----- 268 
XP_015211681        1257 KDGSLVEdapTSPFL--PSPSLKLPLS-----------SSALPNQALGGVSTGL--AMQNLNS------NRQMQS----- 1310
XP_002072610         669 GAGGFATg--RYPVGGgAQPSMSFPPNnl-------mnAGGAGSSGVGGGGNNP--NVSALQV------QKYLSS----- 726 
EDX15213             553 SSGGFAG---RYPVNS-GQPSMSFPHNnlm------nnMGGTAGS--GGGNNNA--NMTALQV------QKYLNQ----G 608 
WGS:AAPU:GI14096-PA  671 NSGGFPQ---RYP----AQPSMSFPPNnlm------tnMSGTAVT----GGNNP--NMAALQV------QKYLNQ----G 721 
EDV90969             656 NSGGFPQ---RYPVSG-AQPSMSFPPNnlm------snMSGTAVT----GSNNP--NMATLQV------QKYLSQ----G 709 
ETN62199             853 glTGHHPSFnQVGVVGIG---GR-------GQQQQHhhhhqhqq--qqqqlaaAAAAQPSNQQLRMLVQQIQLAVQSGFL 920 
ETN64115             794 ggGGVGGPGgNGPPGAFGqplGGgggnvagGLNQPN-----------------AQSQQISNHQLRVLVQQIQLAVQNGYL 856 
XP_001854407         777 ppSGPGGPFnQGGPNGMG---GAggagsggGLGGQN------------------SSAQPSTQQLRMLVQQIQMAVQAGYL 835 
XP_005164151        1188 ---------------GVF---GSsgaaqarALQQQPppqpsvpp--lnssqpsLRAQVPQFLSPQVQAQLLQFAAKNIGL 1247
PNJ88195             269 ------------GNLGMF---GNsgaaqarTMQQPPqppvqpl----nssqpsLRAQVPQFLSPQVQAQLLQFAAKNIGL 329 
XP_015211681        1311 ---------------GVF---SSsgaaqtrAIQQPQpplqqpsvpplsssqpsLRAQVPQFLSPQVQAQLLQFAAKNIGL 1372
XP_002072610         727 ----------QQGPHGVA---SSsasavsvGFGQGSgnaaqtv----niaaanTNNQQPSGQQIRMLGQQIQLAIHSGFI 789 
EDX15213             609 ---QHGVAV---GPQAVG---NSsavsvgfGQNTSNaavagaa----svniaaNTNNQPSGQQIRMLGQQIQLAIHSGFI 675 
WGS:AAPU:GI14096-PA  722 ggPPHGVAL---GPQSVN---ASnasvvgfCQNPPNsapav--------nmasNANNQPSGQHIRMLGQQIQLAIHSGFI 787 
EDV90969             710 --GPHSVAIgGGGPQSVN---ANapv--afCQNASNaapav--------niasNANNQPSGQHIRMLGQQIQLAIHSGFI 774 
ETN62199             921 NHQILNQPLAPQTLILLNQLLN---HIKQMQMTQSNL-ARSGtTGGVSAVQLTLA--INKHKSQIAQLQQQIAAQQSIYL 994 
ETN64115             857 DHQILNQPLAPQTLMLLNQLLN---HIKQLHLMQNNL-ARTG-GGGVNAVQMSLA--INKLKSQITSLQSQIATQQSIYL 929 
XP_001854407         836 NHQILNQPLAPQTLFLLNQLLN---NIKQLQVTQNSL-QRGGaGGNA---QMSM---IPKIKQQIAGLQNQIATQQAIYV 905 
XP_005164151        1248 NPALLTSPINPQHMTLLNQLYQlqlAYQRLQIQQQMLqAQRSvSGPIRQQEQQVArtINNMQQQIQQHQRQLA--QALLM 1325
PNJ88195             330 NPALLTSPINPQHMTMLNQLYQlqlAYQRLQIQQQMLqAQRNvSGSMRQQEQQVArtITNLQQQIQQHQRQLA--QALLV 407 
XP_015211681        1373 NPALLTSPMNPQHMTLLNQLYQlqlAYQRLQIQQQMLqAQRNvSGPIRQQEQQVArtINNMQQQIQQHQRQLA--QALLM 1450
XP_002072610         790 SNQILNQPLTQTTLNLLNQLLI---NIKNLQAAQSSL-SR---GGNANPMAVNVA--IAKYKQQIQTLQNQINAQQAVYI 860 
EDX15213             676 SSQILTQPLTQTTLNLLNQLLS---NIKHLQAAQQSL-AR---GGNANPMAVNVA--ISKYKLQIQNLQNQINAQQAVYV 746 
WGS:AAPU:GI14096-PA  788 SSQILTQPLTQTTLNLLNQLLS---SIKHLQAAQQSL-SR---GGNTNQMVANLA--IAKYKQQIQNLQNQINAQQAVYI 858 
EDV90969             775 SSQILTQPLTQNTLNLLNQLLS---TIKHLQAAQQSL-SR---GSNASPMVVNVT--IAKYKQQIQNLQNQINAQQAAYI 845 
ETN62199             995 KQQQQQQQQQ--QQQQgqqgqPGpipppsllptvAGGGGPP----GGmDFLRQQHDLMALQS 1050
ETN64115             930 KQHQQQQPHQ--QQQQqp-ghPGavnnvnvaalaAATGGHP----GN-DLFRSANDMSGLPS 983 
XP_001854407         906 KQQQQQQQQQ--SGGS------------------SNVGGHL----GG-NFHREQNDLTTLQN 942 
XP_005164151        1326 KQQQQQP--------------PP-----------SHPGLHPnagkSAlDTFPSHPQASSLSv 1362
PNJ88195             408 KQPPPPP--------------PP-----------PHLSLHPsagkSAmDSFPSHPQTPGLPD 444 
XP_015211681        1451 KQQQQ----------------PP-----------PHPGLHPgagkSAlDSFPPHPQAPGLAd 1485
XP_002072610         861 KQQQQQQNLQpnSQQQ-----QP-----------PHPSAHLns-sGN-DYLRGHDAIANLPG 904 
EDX15213             747 KQQNMQPTSQ--QQQPqq---------------qQLFSVHLsn-sGN-DYLRGHDAINNLQG 789 
WGS:AAPU:GI14096-PA  859 KQQNLQQNSQ--QQHQ---------------------SGHLnn-sGN-DYLRNHDAIATLQG 895 
EDV90969             846 KQPNLQQNSQ--QQQQlp------------------sGGHMnn-sGN-DYLRNHDAIGTLQG 885 
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