1HWW


Conserved Protein Domain Family
Glyc_hyd_38C_2

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pfam18230: Glyc_hyd_38C_2 
Glycosyl hydrolases family 38 C-terminal sub-domain
This is a subdomain found in the C-terminal region of golgi alpha-mannosidase II present in Drosophila melanogaster. These proteins are important in glycoprotein processing and are thought to cleave mannosidic bonds through a double displacement mechanism involving a reaction intermediate.This subdomain is found at the C-terminal of Glycosyl hydrolases family 38 C-terminal domain.
Statistics
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PSSM-Id: 408054
Aligned: 6 rows
Threshold Bit Score: 168.117
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HWW_A               926 DLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGtPEEHTQKLDVCHLLPNVA-----RCERTTLTFLQNLEHLDGMVAPE 1000
EDV93140            1017 DLDVVVMRRLTKGTAKKQSIGCVLHRTQLLQCN-EETPPDKFNVCNVLQADDqtsnhRCQRSTLTFLQILEQIEPKVAPQ 1095
WGS:AAQB:GK10956-PA 1015 DLDVVVMRRLSKSKAKAQRVGFVLHRTSLVQCS-SESQAEKFNVCLVLAHTA-----RCERSTITFLDTLGLIESKMAPA 1088
XP_001953431        1015 DLDVTVMRRLTKSSAKTQRIGYVLHRTNLMQCGaDNQLPQKIDVCHLLPNTA-----KCERTTLTFLQTLEQLEPIVAPD 1089
EDX13629            1019 DLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGtPEENAQKLDVCHLLPNVA-----RCERTTLTFLQNLEHLDGMVAPE 1093
WGS:AAPU:GI24010-PA 1019 DLDVVVMRRLTKSTAKRQRVGCVLHRTQLLQCNeEEAPVDTFNICNVLQSGTqrqrqRCQRTSLTFLQNLEQFESQAAPP 1098
1HWW_A              1001 VCPMETAAYVSSHS 1014
EDV93140            1096 LCPMESAAYIISYS 1109
WGS:AAQB:GK10956-PA 1089 LCPMDTEAYVATTN 1102
XP_001953431        1090 VCPMETVAFVSSHT 1103
EDX13629            1094 VCPMETAAYVSSHS 1107
WGS:AAPU:GI24010-PA 1099 LCPMETGAYVISYS 1112
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