O50752 55 DRLLKVYWVIDVKNQNYknscgvDRYSACDIYRLVADLLKKDGKKVVSVRTVQrdlKLL----NEIGLIKTKLRKFGnkd 130 Lyme disease sp... O50966 16 HKSIVLISTLEYINKTH------NKYTQKNILYYFNENLKRNGQLPVKIKTLQ---NYLykleKEIKVTTNYHKHLG--- 83 Lyme disease sp... WP_010883946 19 HKLIVLISTICYLNKTH------KKYTQKTILYYFNENLRKNGQTISTLRTMQ---KYIyrlqKEIKVTTNYYQHMG--- 86 Lyme disease sp... O50717 33 HKLIALIATLEYINKNK------KKYNQSDILYCFNSNLRRNGQKEVSIKTLR---NYFykleK-LNITINYYRHLG--- 99 Lyme disease sp... O50986 16 dRRLKIFWVIQKLSANYfi--skKKYSLSNVVAMTNSILEKKGFKRVTKRTIQndiKIF----ETLGLIKSHFNPLG--- 86 Lyme disease sp... 1_pfamImport 1 QRILKVCWAIDLKNKQYyksnklKTYSTIEIHNIVNKCLAKDNKK-ISIRTLEydiSFL----NQILLIKTKLKHLG--- 72 WP_014696756 13 HKLIVLISTLNYINIKL------KKYNQSDILYYFNNNLENNQQKKVTLKTLQ---SYLykleKEFQVTSNYYKHLG--- 80 Borrelia crocid... WP_014683201 15 YNLIVLISTLNFMNLKL------KQYTQTNILYFFNGNLTRNKQQKVKIKTLQ---NYLyeleKKYKITLNYCKHLG--- 82 Borrelia crocid... O51031 13 HKLIILISTLNYVNSNL------EQYTQNDILYYFNNNIRRNCQKEVKLKTLQ---NYLykleKVFKVTSNYHRHLG--- 80 Lyme disease sp... 2_pfamImport 4 HKLIVLISTICYVNNRF------KKYTQNDILYYFNGNIKRNGQKEVKLKTLQ---SYLyklkKELKVTDNHHKHLG--- 71
O50752 131 nKGKGSIAHYIQNTELvayhkeiiwEHLVQLL--YEKLENKKivGDfdeDIKNAVFNVSktAKFYNANNPLKDLSDTSNg 208 Lyme disease sp... O50966 84 -VNCGTEIYYQLNFSK---------KECYQKI--YKYFQEKK--DL---RFQNRATRGL--KDRFTKNGSVDLKECLNN- 143 Lyme disease sp... WP_010883946 87 -VNSGTEIYYKLNYPK---------KDCYHKI--NQHFKEKK--EE---RYQNRVANYFn-KNSDSKMGSVQLGECNNN- 147 Lyme disease sp... O50717 100 -INMGTEIYYALRHSK---------KDCYNLL--NQHFRNKK--TE---RFQRRVNVYI--KINYDKKDNVKNGECLNNk 160 Lyme disease sp... O50986 87 -KNNGSFTYYTINKAL---------EKLAKKIisTAYFIDKKt------------------KHEKSKNKQLKKIKIIEEs 138 Lyme disease sp... 1_pfamImport 73 -KDNGSFAFYIQNKNLwkhrfiiiqEAINKEI--KEYLKDKKivSDffkEINNTIN-----------KNNIRNIK----- 133 WP_014696756 81 -ENRGTEIHYKLKHHK---------KVCHYKI--NKYFKEKK--EE---RFQKRANSYH--TKSCNNNGNVEKWESIYNy 141 Borrelia crocid... WP_014683201 83 -KQCGSEIYYKLKYPK---------KTCHTKI--NQYFRNIK--KEkidKFTKRIETYI-------QENGSPKWECINNi 141 Borrelia crocid... O51031 81 -INMGTEVHYKLKYPK---------KVCYHLI--NKHFKEIK--KK---KYKSRVDSYF--NKNCIENSSVKNRECFYNi 141 Lyme disease sp... 2_pfamImport 72 -INMGTEIYYKLKYSK---------KECYRQI--NKYFKNKK--ED---KFQKRITKNE--KKIYNKNGSVEKWECINNi 132
O50752 209 aSNFSNNFSDKFSRHSERLSENIFLKsscdtvltnqdvdsrttmsrhsppavfnkanisysnYKNSKNSLCNSKiqknnI 288 Lyme disease sp... O50966 144 -KNNIKEERKINEIEKYQVRNYFNKC------------------------------------NFLCKKILSIFLtilfnL 186 Lyme disease sp... WP_010883946 148 -NNNIKEERKINEIEKYQVIKYFNKC------------------------------------DFSCKEILPVLLt----L 186 Lyme disease sp... O50717 161 yKKEERETERKKRINKLKLKKYAKKC------------------------------------NFDNEISSFIIN-----L 199 Lyme disease sp... O50986 139 qKYK-----ISHQITSHVLSNNISKK------------------------------------YKNSKYSFRRKN-----Q 172 Lyme disease sp... 1_pfamImport 134 ---------PKSSIADESIADVIPKGik---------------------------------gINKIENSIEKNNgkinkI 171 WP_014696756 142 -NNKKNKEEEKKEREQKQLEKYAEKC------------------------------------KFKDDKYLSILN-----L 179 Borrelia crocid... WP_014683201 142 nNN--------KKIEERILKKYISKC------------------------------------HFKIDLPLVLLN-----S 172 Borrelia crocid... O51031 142 sNNKEEKRNSRKSIEKLQIRKYIEKC------------------------------------NFKSNIFSLILN-----L 180 Lyme disease sp... 2_pfamImport 133 yNNKREYK-DKKLKEESQVKKYAKKC------------------------------------HFKSKEFLSILN-----L 170
O50752 289 NFeKKDIETKLIERNIPKDFLSR--------------------------------------IKDLSNNPTTYKNALYNLD 330 Lyme disease sp... O50966 187 DI-DKDNIIKILKIIKIIEIKLLknkn------------------------------ihftKSCMKEKQEKLKKILCNTQ 235 Lyme disease sp... WP_010883946 187 NI-DKENIIKIIKILKITEINSknkn-------------------------------irptKSCIKKKQEKLKGILCNTQ 234 Lyme disease sp... O50717 200 NL-KKETTIKLFKFIIKEKYYFKkenk-------------------------------cnlQKTLQNKKRDLISILRKTQ 247 Lyme disease sp... O50986 173 NI-KKTINFLEKEIKKKSKSINLe------------------------------------eIKKITENDITYKNSLWNLK 215 Lyme disease sp... 1_pfamImport 172 SY-KEYIANKLVEVHKIEKMQITk-------------------------------------ILKISNNEKTYINALRNLK 213 WP_014696756 180 EA-TKEIKIKKLIELKKEENKRKkeq---------------------------------nkSRKLVEKQKELEKTLTTKK 225 Borrelia crocid... WP_014683201 173 KI-EKDLKIELIKEIKKHERAIEalsldeinllkekliegtpncvkgflegmgylknteskIKKQEIKLRKLKEILDLKR 251 Borrelia crocid... O51031 181 GL-KKDATIEVCKMIKKAENLIEknifekl------------------------nvvkvieVNKLKNKQQKLKRILKEVK 235 Lyme disease sp... 2_pfamImport 171 DI-NKDDKIRILKAIKRAENYIMnnfseki-------------------------ndfiinRNKLKSKQEKLKEVLNEIK 224
O50752 331 KALDEHNESNLKYVLEh-fLDQF-SIYRYKVWMMmkrrdgvisdyevIWKERF-----GEFVKK------------KVEL 391 Lyme disease sp... O50966 236 KEFEKNEYNPKQLEIS---FQKIyENYKFKPHFI-------------IESHKYsd--lNNIKRKleksierkkensQQNY 297 Lyme disease sp... WP_010883946 235 KELEENGYNPKQLEIN---FQKIyENYKYKPHFI-------------IENHKYsd--lNNIKRKleksierkkensQQDY 296 Lyme disease sp... O50717 248 KILIKEGCDKKKIKTQ---IQNTyQKYKNKPHFI-------------LESNKYkd--fDQIIKKikddt--nktepQKHK 307 Lyme disease sp... O50986 216 DFMEELKEYEEKKIIKf--YKKNlEKKKQKIWFM---------------AKKFkntdfDKLIKKfkiknkmereknYENE 278 Lyme disease sp... 1_pfamImport 214 LAIEKYKEEYKIEDISnhfIKEFkNKYSKKIWMMngktdr-tndfyeIWEKRFkktflNKNLKKqyr-------snYEKE 285 WP_014696756 226 EDLEKEGYDKKQLEIE---MQKAyGKYKDKPHFI-------------IESSKYgd--lGQIVKRikrtveckkkekKEDR 287 Borrelia crocid... WP_014683201 252 KELESQNYKEDVLNQE---INKIyERYKNKPHFI-------------IEQDKYrd--lDLLIQKikknte-kckskTKER 312 Borrelia crocid... O51031 236 IKLENENYKSEQLEIE---IKDIyEQYKNKPHFI-------------IEKNKYed--lEKITEKlknkfkqekiniKEND 297 Lyme disease sp... 2_pfamImport 225 TQLESEKYDSKQVEMQ---IQEAyERYKNKPHFI-------------IEDDKYdd--cKKMINKiknsiknfnknvEKNE 286
O50752 392 NdYVKKVLSM 401 Lyme disease spirochete O50966 298 Q-DLKTNIFN 306 Lyme disease spirochete WP_010883946 297 E-NLKINVFN 305 Lyme disease spirochete O50717 308 D-NIETNIYN 316 Lyme disease spirochete O50986 279 N-QIHTSNNI 287 Lyme disease spirochete 1_pfamImport 286 N---KKIINN 292 WP_014696756 288 Q-QIKDNIFS 296 Borrelia crocidurae WP_014683201 313 D-DIKNNIFS 321 Borrelia crocidurae O51031 298 T-NIRNNIFN 306 Lyme disease spirochete 2_pfamImport 287 Q-TVRVNIFS 295
Jiyao W et al.(2023). "The conserved domain database in 2023.",