5LP2


Conserved Protein Domain Family
SabA_adhesion
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pfam18304: SabA_adhesion 
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SabA N-terminal extracellular adhesion domain
This is the N-terminal extracellular adhesion domain of Sialic acid binding adhesin (SabA) present in Helicobacter pylori. The N-terminal domain of SabA functions as a sugar-binding adhesion domain with conserved disulfide bonds. Notably, these amino acid residues are not only conserved among SabA orthologs but also between SabA and BabA.
Links
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Statistics
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PSSM-Id: 375731
Aligned: 5 rows
Threshold Bit Score: 322.246
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5LP2_A  12 VQKLSDTYEQLSRLLTNDNGTNSK----TSAQAINQAVNNLNERAKTLAGGTTNSPAYQATLLALRSVLGLWNSMGYAVi 87 
O25086  46 IQQLSDNYENLNNLLTRYSTLNTLiklsADPSAINAVRENLGASTKNLIGDKANSPAYQAVFLAINAAVGLWNTIGYAV- 124 Helicobacter pylori
O34523  44 LQNLADRYDNLNNLLNQYNYLNSLvnlaSTPSAITGAIDNLSSSAINLTSATTTSPAYQAVALALNAAVGMWQVIALFI- 122 Helicobacter pylori
O25791  47 VQKLSDTYEQLSRLLTNDNGTNSK----TSAQAINQAVNNLNERAKTLAGGTTNSPAYQATLLALRSVLGLWNSMGYAVi 122 Helicobacter pylori
O24870  46 IQDLSDSYERLNNLLTSYSALNTLirqsADPNAINNARGNLNASAKNLINDKKNSPAYQAVLLALNAAAGLWQVMSYSIs 125 Helicobacter pylori

5LP2_A  88 CGGYTKSPGENNQKDFHYTDENGNGTTINCGG-STNsngthsyngtntlkaDKNVS-LSIEQYEKIHEAYQILSKA--LK 163
O25086 125 MCGNGNGTESGPGSVIFNDQPGQDSTQITCNR-FES---------------TGPGKsMSIDEFKKLNEAYQIIQQAl-KN 187 Helicobacter pylori
O34523 123 GCGPGP--TNNQSYQSFGNTPALNGTTTTCNQaYGT---------------GPNGI-LSIDEYQKLNQAYQIIQTAlnQN 184 Helicobacter pylori
O25791 123 CGGYTKSPGENNQKDFHYTDENGNGTTINCGG-STNsngthsssgtntlkaDKNVS-LSIEQYEKIHEAYQILSKA--LK 198 Helicobacter pylori
O24870 126 VCGPGSDKNKNGGVQTFENVPSNGGTTIACDSfYEP---------------GKWSG-ISTENYAKINKAYQIIQKAfgAS 189 Helicobacter pylori

5LP2_A 164 -QAGLAPLNSKGEKLEAHVTTSKYQQ--------------------------------------------DNQTKTTTSV 198
O25086 188 -QSGFPELGGNGTKVSVNYNYECRQTadinggvyqfckakngsssssnggngsstqttatttqdgvtittTYNNNKATVK 266 Helicobacter pylori
O34523 185 qGGGMPALNDTTKTGVVNIQQTNYRTttqnniiehyyt---------------------engkeipvsysGGSSFSPTIQ 243 Helicobacter pylori
O25791 199 -QAGLAPLNSKGEKLEAHVTTskp--------------------------------------------enNSQTKTTTSV 233 Helicobacter pylori
O24870 190 -GQDIPALSDTKELNFEIKGKKNDSVqpgerwkfpwt-----------------------ngkfvsvkwvNGKYEEIKED 245 Helicobacter pylori

5LP2_A 199 IDTTNDAQNLLTQAQTIVNTLKDYCPILIAKSSSsnggtNNA-----NTPSWQ--TAGGGKNSCATFGAEFSAASDMINN 271
O25086 267 FDITNNAEQLLNQAANIMQVLNTQCPLVRSTNNE-----NTP-----GGGQPW--GLSTSGNACSIFQQEFSQVTSMIKN 334 Helicobacter pylori
O34523 244 LTYHNNAENLLQQAATIMQVLITQKPHVQTSNG----------------GKAWg-LSSTPGNVMDIFGPSFNAINEMIKN 306 Helicobacter pylori
O25791 234 IDTTNDAQNLLTQAQTIVNTLKDYCPMLIAKSSS-----ESSgaattNAPSWQ--TAGGGKNSCATFGAEFSAASDMINN 306 Helicobacter pylori
O24870 246 IKVSNNAQELLKQASTILTTLNEACPWLSNGGAG-----NVA-----GGNSLWagIDKGDGSACGIFKNEISAIQDMIKN 315 Helicobacter pylori

5LP2_A 272 AQKIVQETQ---QLSANQPKNiTQPHNLNlnsPSS--LTAL 307
O25086 335 AQEIIAQSKivsENAQNQNNL-DTGKPFN---PYT--DASF 369 Helicobacter pylori
O34523 307 AQTALAKTQ---QLNANENAQiTQPNNFN---PYTskDKGF 341 Helicobacter pylori
O25791 307 AQKIVQETQ---QLSANQPKNiTQPHNLNlntPSS--LTAL 342 Helicobacter pylori
O24870 316 AEIAVEQSKivtANAQNQHNL-DTGKAFN---PYK--DANF 350 Helicobacter pylori
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