Conserved Protein Domain Family
SH3_and_anchor

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TIGR04211: SH3_and_anchor 
SH3 domain protein
Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Statistics
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PSSM-Id: 275056
Aligned: 49 rows
Threshold Bit Score: 118.572
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
REF_jgi:Pcar_0499  53 YITDQIPVTLRRGPGNEYRILKSLTSPASIEILEDNDN--YFKVRTADGTEGYILKQYVIRQEPSAVIAARLQREQTVLR 130 Pelobacter...
ZP_01215415        25 YVSDNIFIYLHSGPGLDYRITGTVKVGTPLKTLKYDSNskFMKIKLPNGREGWVKNNELQTTPPAKTRLPAVKKELLAAQ 104 Psychromon...
ZP_01166995        22 HIADDAMVYVHNGPSNSYRIITRIKSGTPVTILKRDASskYVQIKMPKGRIGWVEPTAVDPGDSISVRLPKLQSDLEQSQ 101 Neptuniiba...
ZP_05060949        13 YIKDDWKVGLYSQPNSQSQGLGLLDMGESLSVLEVGAD--FSKVKTQDGREGWVGNRYLVENPTLVQTMQSAQNQIAKLE 90  gamma prot...
ZP_05704525        24 WISDELRTAVYDKPASDAKFLGTLRSGEAVEMLDRNGD--YIHVKTGE-LNGWVSARSIMETPSVHSRFAEQQQQLQQLQ 100 Cardiobact...
WP_011507629       29 WVSDQLPTYVRSGPTDGYRIVGTLDSGEPVTLLERQND--YSRVRSQDGDTVWIPSRYLQDTPSARSRLPELQTRVDELT 106 Chromohalo...
WP_012738027       28 YISDNLTTYVHSGPGDEYRILGVLKAGEPVTLLDVHTTtqYAQIRDKKGRVVWLPAKQLSQVPSQLSRLPDLEQKIKNLT 107 Candidatus...
WP_011044929       34 YISDELFIYMHTGPGKQFRILGTIIAGSKVKITGAVDGg-YSEIIDNKDRTAWVENKYVTTQPGLRFVVAELNGKIANSS 112 Colwellia ...
WP_015731120       27 YISDELLTYVHSGPGNQYRIVGTVNAGTEVTLLSVNESagYAQIRDDKNRTTWIPLDQLSNTPSLRTRVPELEKQVKDLT 106 Pectobacte...
WP_010945231       23 YITENLSTYMRKGAGDQYKIAGTIQAGEKITVLDR-KDr-FVLIRDSRNREGWVLNNEISQTASPKELIPELQQQIQDLS 100 Haemophilu...
REF_jgi:Pcar_0499 131 KKVDELRQQNQDFQALQAENRTLLQQTETELRKVQGDYDKLRKGAQNITETMAERDRLQQENEEQLQKIAALEKENRYLW 210 Pelobacter...
ZP_01215415       105 NKLSATIENNKNNLAVKAQ--------------------SNNDLDELILSLRNDKSALEKTILDLQAKNLELDLLQDTKE 164 Psychromon...
ZP_01166995       102 TMVKEQAEKIVELQQESK-------------------------------NLKNTNESLNSEVQQLKAKIKDLNFQIESSD 150 Neptuniiba...
ZP_05060949        91 DQIEMMASDS-----------------------------GMDKLKEALKAAEAEKLTMGELIAELKEDNEALKAVSDPKA 141 gamma prot...
ZP_05704525       101 GEAQNLQNTTNDQNQSLDALKARLEALQAAEQKARDELVALQRASGNAIAIDQRNRELQAAVVNLEQENLSLKHRNTRLE 180 Cardiobact...
WP_011507629      107 SELDGINQEWEQRVADMKT--------------------TLDERGQRIEELEARNAELNSAYGEAQETVRGLEARLDTQE 166 Chromohalo...
WP_012738027      108 DQLNDTHHRLKERSQEIQE--------------------KIALSEKLIEGLKSENKGLKEQLTIRNQQINEIENKTNAEK 167 Candidatus...
WP_011044929      113 DYSSQLDGEVNELKSKVN-------------------------------LLTNDKKKLSAELKKLTTTLEKTQAKIKDQD 161 Colwellia ...
WP_015731120      107 DKLNNIDQTWNQRTADMQ--------------------QKVAASDNIINGLRQENQDLKNQLIVAQKKVSAANVQLDDKQ 166 Pectobacte...
WP_010945231      101 SKLNKIDNDWQQRTAEMQR--------------------RSQQAEQQSSELLDENTQLKRKLEVLKNKNRDLETMQDAEK 160 Haemophilu...
REF_jgi:Pcar_0499 211 -RNNILRWFFAGVGVLCLGWLLGRRp-------pRRTRS-----F 242 Pelobacter carbinolicus DSM 2380
ZP_01215415       165 -DRVQMEWMLNGGGVLLFGLIVGLLlpfl--prrKKRKSg---gW 203 Psychromonas sp. CNPT3
ZP_01166995       151 -ESNLMRWFTHGGLVALGGVFLGLIlpy---fpkRRKRKd---eW 188 Neptuniibacter caesariensis
ZP_05060949       142 iEQQRLESMVTAITLCFVGLVVGFLvgkrlieskVRARFngmkvW 186 gamma proteobacterium HTCC5015
ZP_05704525       181 -ENLNQKQLYIGGFLVFAGFVLHWLsglfrlgqrRRSSFd---dL 221 Cardiobacterium hominis ATCC 15826
WP_011507629      167 -QDLLMRYFMYGAGVAGAGLLVGLIvph---lprRRKRRs---gW 204 Chromohalobacter salexigens
WP_012738027      168 -NNIMMKWFTYGGMVAGTGFILGLLlpfl--iprRKRNHr----W 205 Candidatus Hamiltonella defensa
WP_011044929      162 -TNIKKQWFFNGALVLGVGLILGLIlprf--farRRGAMd---sW 200 Colwellia psychrerythraea
WP_015731120      167 -RTIILQWFMYGGGVAGIGLLLGLLlphi--iprKKK-Nd---rW 204 Pectobacterium wasabiae
WP_010945231      161 -REIVIQWFIYGGSVLTVGLLLGLLipfi--lprRRR-Nn---gW 198 Haemophilus ducreyi
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