Conserved Protein Domain Family
VI_FHA

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TIGR03354: VI_FHA 
type VI secretion system FHA domain protein
Members of this protein family are FHA (forkhead-associated) domain-containing proteins that are part of type VI secretion loci in a considerable number of bacteria, most of which are known pathogens. Species include Pseudomonas aeruginosa PAO1, Aeromonas hydrophila, Yersinia pestis, Burkholderia mallei, etc. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Statistics
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PSSM-Id: 274537
Aligned: 15 rows
Threshold Bit Score: 352.828
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_014602337   3 LRLTITSYHKLTPGQCSEKVLDQGQ----LTIGRGPDNDWVLPDPERLVSSRHCTILNRDGVYYLTDTSTNGVLLVNAGH 78  Pseudomonas aer...
WP_005463793   3 LVLTITSFHKFTPEIESEFVFESSDehakVTFGRSEQCDWTLPDPERVISGTHGELIKFGDKYLIKDLSTNGTFVNNAVT 82  Vibrio parahaem...
WP_011152284  32 IVLSITSFHRFTPEIKSVYSIPTNEehfcMKFGRSESCDWVLPDPERIISGVHGEITKFGNDYLLRDLSTNGIFVNKSVS 111 Vibrio vulnificus
WP_011705717   8 LSLVVLNSEQLDGSQQVQYRFDEMG----GTLGASEQDDWQLRDRLGAVMPAHARIELNDGRFCLCDLS-GQTYINGATS 82  Aeromonas hydro...
WP_011144756   8 LSLRVINSDQLESGKAASCLFSTQG----GTVGSSESHLWSVQDQQGNINPSQFTIQWRDDAFCLQMIA-GPLFVN--QS 80  Photorhabdus lu...
WP_011094948   7 LTLVVLNSEQLDINSQVQHQFDHRG----GTLGASEKDQWQLRDRLGSVVPAHARIEMTDGYFSLCDLS-GQSFINGSLS 81  Pectobacterium ...
WP_001362877  13 LTLQVMNGNELESGRAAKCLFSENG----GDIGHTPECHWQVQDRAGSIAARACTVIRHDGAYCLRCL-TPGLMIN--LA 85  Escherichia
WP_010910862   3 ITLQISNVDRLPPGIAASYAARDRS----FEIGR-ENCDWTLSDPDKFISGRHCEIRYQAGTFWLHDVSRNGTFVNGSSQ 77  Mesorhizobium loti
WP_017140385   2 LRLVIE--HAPCPQRVGEMRLEAGE----LSIGRGADCDWQIDDPDMFVSRRHCIVSGGEGGWLVIDASRGGLFLDGSES 75  Rhodobacter sph...
WP_011348996   6 LILTVSGAQAAQFGASAQKRFAGTG----GSIGRSDESDWVLAAPG--VSRTHAVVRFLNGMYFIEDRSTNGMSLN--GT 77  Xanthomonas euv...
WP_014602337  79 RLRRGN-SEPLQDGETVRLGEYDILVQL--------------GhdialpgsgnpqtD----------------------- 120 Pseudomonas aer...
WP_005463793  83 PIGQGN-ELALSHGDTVALGDYQIQISI--------------S-------------D----------------------- 111 Vibrio parahaem...
WP_011152284 112 PVGNGV-EVALNDKDVINFGDYEIEVSFk--------------------------------------------------- 139 Vibrio vulnificus
WP_011705717  83 PIGRAR-KVHLEQGDELVVGPFRLRAYL--------------G-------------A----------------------- 111 Aeromonas hydro...
WP_011144756  81 PLTSGAgFIRLQQADEITIGKLVIKSYIsfsdtdridpmtvsP-------------E----------------------- 124 Photorhabdus lu...
WP_011094948  82 PIGRDR-KVILSHGDELVIGPFRLGVYI--------------G-------------D----------------------- 110 Pectobacterium ...
WP_001362877  86 PASSDA-LIRLRQGDEIQLGALALKVFL--------------H-------------Dgaavty--------------der 123 Escherichia
WP_010910862  78 RMNA---PHRLTQGDRLLIGRYVVAVSV---------------------------------------------------- 102 Mesorhizobium loti
WP_017140385  76 PLGAGN-SAVLAQGTRLRLGDVVLRAEI--------------Egre-------plrA----------------------- 110 Rhodobacter sph...
WP_011348996  78 ALTRAD-PSALSDGDRLQLDSFEIQVQV--------------Q-------------Slaaaspatpvfdplpdamddrtq 129 Xanthomonas euv...
WP_014602337 121 ---Pfts-------fdaLMSRqAAGSAPAFAEPaPTPHPAVTAh--F----------QGGSPLD---------------- 162 Pseudomonas aer...
WP_005463793 112 ---I-------------SEDR-TEHQFTSNPEV-KTPVGFEQH---V----------ESIPEME---------------- 144 Vibrio parahaem...
WP_011152284 140 ----------------nSEKH-NVTQSQIHTNT-LSPREVn-----K----------EPVSGND---------------- 170 Vibrio vulnificus
WP_011705717 112 ---ItpeqslqqvlgnrPTEQ-LDEWLTSD-EP-VVPADDPRTl-aA----------DPLLALQ---------------- 158 Aeromonas hydro...
WP_011144756 125 ---SlvssysnpldammEKDP-AQDSAFTDHGS-LAPTIKHDFs--H----------DPLKVLD---------------- 171 Photorhabdus lu...
WP_011094948 111 ---PtteqdidqvlgqrTDDV-LGGWLSEDKKR-RSTDLADSTvvlN----------DPLWALQ---------------- 159 Pectobacterium ...
WP_001362877 124 matPeti-------vmnRDSL-ADTLLTTEGQP-AYPGMPFQHq--LaptvahgfssDPLQALQ---------------- 176 Escherichia
WP_010910862 103 -----------------DEER-VATGHPQARTG-STQRELPPSt--G----------TPLK------------------- 132 Mesorhizobium loti
WP_017140385 111 ---Plap-------reaALAV-DDFFAAPRAVT-PEPPPRPKDl--P----------GPFEAVE---------------- 150 Rhodobacter sph...
WP_011348996 130 vapPpst-------lraPSAT-AGFELLEFGTP-PAARPAVDAv--L----------DELLLSGasreldplrlldplpa 188 Xanthomonas euv...
WP_014602337 163 ---TKPdlfdfltppppgaaprpdhvpaeqhdfrppepvippppattpapppaggapLIPADWDPfaellgnTPAPSATP 239 Pseudomonas aer...
WP_005463793 145 ---DFG---------------------------------------------------LSAAELMD-------ESVPSDFQ 163 Vibrio parahaem...
WP_011152284 171 ---NFM---------------------------------------------------DFGFDANLflaeeekQQQNLSPE 196 Vibrio vulnificus
WP_011705717 159 ---QER---------------------------------------------------RAPNPLMDgpladgrLQASLRSQ 184 Aeromonas hydro...
WP_011144756 172 ---SEN---------------------------------------------------LTTLDQTS-------VSNEVDQS 190 Photorhabdus lu...
WP_011094948 160 ---KEQ---------------------------------------------------SQ-----S-------LLLSDSET 173 Pectobacterium ...
WP_001362877 177 ---TES---------------------------------------------------LMVADD------------PIAPR 190 Escherichia
WP_010910862 133 ------------------------------------------------------------------------LGSALFHN 140 Mesorhizobium loti
WP_017140385 151 ---RAP---------------------------------------------------APPPQDDFgfg--waLPAQVRPP 174 Rhodobacter sph...
WP_011348996 189 parDAS---------------------------------------------------PSAWNQSN-------ARHDHFRP 210 Xanthomonas euv...
WP_014602337 240 VA-----Qpl-ptAEPTPLAMPF-A--D--PGITQlpqpqpqpqpqpqpqpqpqpqpqpqPQPqPASVAAPTPPASAAAS 308 Pseudomonas aer...
WP_005463793 164 LD-----I-----GLVDDFLEIP-S--H--ETEVP-------------------------QPK-VASMQPDTNAKSQKPT 202 Vibrio parahaem...
WP_011152284 197 LG-----------DLDDFLDAPI-L--S--PHIEP-------------------------TLKeE-RATDYPRDEKVAKR 234 Vibrio vulnificus
WP_011705717 185 PD-----V-----DVPPLAPFSA-V--E--NTMNQ-------------------------EFLdMPAIENHPDYQLSLDG 224 Aeromonas hydro...
WP_011144756 191 LQ-----Qdh--yRTPLFFSSLS-D--NrgNAMDQ-------------------------DFVdLPGISSPFNEQYQDME 235 Photorhabdus lu...
WP_011094948 174 VG-----E-----SLTTSLSSFSsA--E--DTMDQ-------------------------KFVeLPTINTRYAGDELEGY 214 Pectobacterium ...
WP_001362877 191 V------S-----RPVAPASDLT-G--A--NGINT-------------------------PFMdLPPGNARHEDGDEFSA 229 Escherichia
WP_010910862 141 LG-----E-----QRPAEVTPVP-A--S--SVLQS-------------------------SPA-VPAKQPGEAE------ 173 Mesorhizobium loti
WP_017140385 175 PA-----EarkteGQDPFFRPGT-AteN--PSLEA-------------------------SPAp---PQARSAPRELALS 218 Rhodobacter sph...
WP_011348996 211 PAspdarA-----TLPENWDMTL-G--D-----FA-------------------------PPApLPAVSPMAAP------ 246 Xanthomonas euv...
WP_014602337 309 AGGD--L--LQAFLRGAGMTQLKVDPAGAEAQMEAIGRSYRGLVEGLVDVLRARASLKGEFRMAQTMIQPVQ-NNPLKFA 383 Pseudomonas aer...
WP_005463793 203 VHRG--E--LEAFIYGMGIDPNMVPSQNREQWFEQLGQSFSLMLIGLMETLHNRAVFKQTNRVNHTAFRKSE-NNPLKFS 277 Vibrio parahaem...
WP_011152284 235 CERV--DsdLNAFLEGAGIDLSLVPEQEREQWFNRLGRSYSLMLEGLMQTLHNRAEFKQANKLNHTSFQKKE-NNPLKFS 311 Vibrio vulnificus
WP_011705717 225 VDHV--A--LTPLMRGLGQPLQLQDTQQAHDMLEEMGKTVRAMVEGLLQLQNEQAALAD------KHLRPIE-DNPLRLG 293 Aeromonas hydro...
WP_011144756 236 QQHV--A--ITPLMRGLNTQLPLHNSQQANDFLEEMGKTMKAAIEGLLVLQRTQHGLRD------KQLRPIE-DNPLRLN 304 Photorhabdus lu...
WP_011094948 215 SDGT--S--LAPLMRGLGLSLQPSDDARLREMLEEMGKSLRAMVEGLLALQTEQAALAD------THLRPIE-DNPLRLG 283 Pectobacterium ...
WP_001362877 230 MAQYhlA--VTPLLRGMECPLTLHNSQDADEFLEEAGRALQAAIKGLLSLQQQQNSLSD------KHLRPLE-DNPLRLD 300 Escherichia
WP_010910862 174 ---G--I--LRDIARAAGLSPELLQSRDPHDVAAEIGAVLRTTVEQLSLLLKARAAAKVLAKSAHRTMIGAEdNNPLKFV 246 Mesorhizobium loti
WP_017140385 219 EDA---L--SEAFFHGLGLPSEALDTAA----MEAMGRRFRLLAEGLVLLLRARSREKGAARVPQSVIGASE-VNPLKFL 288 Rhodobacter sph...
WP_011348996 247 ------V--VSPFTSPA--APVAAAASAATTVPPELDRIFAIVVDGVMDVLRARAEIKNTFRLPVTVIQRSE-NNPLKFA 315 Xanthomonas euv...
WP_014602337 384 PNVDEAMLLLLRR-DNQAFMAPDRAVADSFEDLKAHQLAVMAGVQAAIRHLLARFEPAALEARFGKPAGLSG-LLPGARQ 461 Pseudomonas aer...
WP_005463793 278 ANLEDAIHNLYNR-QTSSFLKPNAAIKEAFNDIENHEQALMQGVAGTVSSVMSLVEPNTIYSDALAKDNVINkVIPARKY 356 Vibrio parahaem...
WP_011152284 312 ANLEDAIHNLYNR-RSASFLSPEAAIQSAFNDIEAHEKAMIEGVHGAVSGVLRLLEPNTISGHVSQSEKNGLtSIFSQLD 390 Vibrio vulnificus
WP_011705717 294 LDYDETLAVLFAEqKSPVHLSAPAAVAESLHNVRIHHVANQQAIGAALDSILQAFSPQALLGRFEQYRRSG--APGTADE 371 Aeromonas hydro...
WP_011144756 305 MDYNTTMQVMFADqKSPVHLSAPSAVAESLHNLQLHYQANRIAITAALNTMLDAFSPEHLLNRFAQYRRSNE--TQEKDA 382 Photorhabdus lu...
WP_011094948 284 LGYADTLSVLFAEgKSPVHLSAPAAVEEVLNNMRVHHIANQQAIAVALENILQAFSPAALLSRFEHYRRSGE-PL-AADD 361 Pectobacterium ...
WP_001362877 301 MDYATALNVMFAEgKSPVHLAAPAAIAESLRNIRHHEEANRAAIVEALRVMLDAFSPGNLMRRFAQYRRSHE-LRQKMDD 379 Escherichia
WP_010910862 247 PGTDDILEIMFAK-RRAGYLDARHSIEDAFRDLKTHEIATYAAMQAALSRLLDDLSPEAIAKRIPP-------ASFSSRK 318 Mesorhizobium loti
WP_017140385 289 VTLDEAVAALVTP-RGPGYLGPEASIEGAFRDLTDHQLRNWIAVQAALRRMIDRFDPARFEAESEREGRMAQ-LLAGGRS 366 Rhodobacter sph...
WP_011348996 316 ATAEDALQKLLAP-PSASFLSGVPAFEDAFDDIRCHQMAMLAGMRAAFDAMLFHFSPDRLEQEADAGGKR---LSFGGK- 390 Xanthomonas euv...
WP_014602337 462 AQNWDSFTELYAKILREAEDDFQELFGREFSRAYEEHSA 500 Pseudomonas aeruginosa
WP_005463793 357 AQSWKRFEGIHSQLTDELVNKESPFYLEDFAKHYELALK 395 Vibrio parahaemolyticus
WP_011152284 391 KKRWKKYENIYFQIRNEIDIDEKGFYLEDFSKSYESAIR 429 Vibrio vulnificus
WP_011705717 372 GWAWDMYQHYYRELTSARQQGFDKLFHQVYAQAYDQAVR 410 Aeromonas hydrophila
WP_011144756 383 TWAWEMYTSYYRELASSRQQGFEKLFGEVYEQAYDRALR 421 Photorhabdus luminescens
WP_011094948 362 GWAWQMYQHYFRELTSPRQQGFQKLFHQVYAQAYDRAVR 400 Pectobacterium atrosepticum
WP_001362877 380 AWAWQMYSNYYDELASSRQQGFEMLFNEVYAQVYDRVLR 418 Escherichia
WP_010910862 319 SQAWDALVATWRTMEDKHENGMLDVFLAYFAEAYAKADK 357 Mesorhizobium loti
WP_017140385 367 ARLWQLYLDRYEELARAAEDRFLGEVGADFREAYEGPER 405 Rhodobacter sphaeroides
WP_011348996 391 GRYWERYRDNFEQLRSDPDECFRRLFGDEFARAYEAQLA 429 Xanthomonas euvesicatoria
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