2XWU


Conserved Protein Domain Family
Importin_rep

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pfam18773: Importin_rep 
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Importin 13 repeat
Importin 13 has a spiralic structure containing repeats structurally similar to HEAT repeats. It serves as receptor for nuclear localization signals (NLS) in cargo substrates, mediating docking of the importin/substrate complex to the nuclear pore complex (NPC). It contains several repeats structurally similar to the HEAT repeat. This Pfam entry represents a single repeat unit.
Statistics
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PSSM-Id: 436727
Aligned: 13 rows
Threshold Bit Score: 77.023
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2XWU_B        402 QFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAE 441 
EEN47427      385 QYPPDSEYASWTAEEKEQFRCYRQDIADTLVYAFNLLRDS 424 
KOF80503      239 QYPPDQEYNSWSTEQKEQFRCYRHDIGDTMMYSFTILKDF 278 
ESO93597      389 QHPDDKEYASWTADEKEQFRCYRQDIGDTMMYAFNILQEP 428 
XP_013399867  397 QYPSDEVFAGMNNEEKEQFRCYRQDISDTMMYTYGILRES 436 
PIK44010      402 QYPSDKEYTSWTLEEKEQFRCYRQDISDTFMNCFSLLHEP 441 
XP_008198199  414 MFPLNED-GDWSLDDKEVFRCYRQDIADTFIYCYNVLNLE 452 
XP_018334259  414 qYPGSWEESGWSLDDQEVFRCYRQDITDTLMYCYNILNVE 453 
ORX90935      411 EYPSEEEWSSWSKDVRERFKIYRRDVGDTLINSYLVLHGE 450 
XP_002128195  392 KYPQDNSHNEWTADEKEQHRIYRIDISDTLMYLLEMLHTD 431 
XP_014342856  394 QFPTDEEYGTWSSDEKEQFRIYRVDVSDTLMYVYEMLGAE 433 
XP_694685     385 CFPRDEDFTAWSADDKEQFRTYRVDISDTLMYTYELLGPE 424 
EKC31329      329 QYPEEEEYNSWTKDDKEEFRCYRQDIGDTMMYSYSILREP 368 
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