Conserved Protein Domain Family
CAF1-p150_C2

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pfam15539: CAF1-p150_C2 
CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
CAF1-p150_C2 is part of the binding region of the CAF1 complex p150 subunit to the p60 subunit. The CAF1 complex is essential in human cells for the de novo deposition of histones H3 and H4 at the DNA replication fork.
Statistics
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PSSM-Id: 434777
Aligned: 5 rows
Threshold Bit Score: 535.341
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q13111       665 AKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEEQTPK---ASKRERRDEQILAQLLP 741  human
EHB14613     638 AKEWDEFLAKGKRVRVLQPVQIGCVWADDTGCSTADLKVLQQFTAWRLESAPSEDKLVPK---ATKREKRDQQILAQLLP 714 
XP_003788927 659 AQEWDEFLAKGKRFRVLQPVKIGCVWAADGDCVGADLKVLQQFTACLLEPVPAEEEQTPT---ASKKEKRDQQILAQLLP 735 
XP_014978011 666 AKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETVPVQEEQTPKaskASKRENRDQQILAQLLP 745 
XP_011286108 651 AKEWDEFLAKGKRFRVLQPVKIGCVWAADKD-GGADLKVLQQFTACLLETVPSEEEQTPK---ASKREKRDQQILAQLLP 726  domestic cat
Q13111       742 LLHGNVNGSKVIIREFQEHCRRGLLSNHTGS-P-------RSPSTTYLHTPTpsEDAAIPSKSRLKRLISENSVYEKRPD 813  human
EHB14613     715 LLHGNVNGSKAIIREFQEHCRRGLLSVGGASsP-------PSPTTPRPHTPT--EDTAVPSKARLKRIISENSVYEKRPD 785 
XP_003788927 736 LLHGNVNGSKAIIREFQEHCRRGLLTGGASS-P-------PSPASSCPQTPT--VDTAIPSKALLKRIISENSVYEKRPD 805 
XP_014978011 746 LLHGNVNGSKVIIREFQEHCRRGLLSKHTGS-P-------PSPSTTCLHTTS--EDAAIPSKSRLKRLISENSVYEKRPD 815 
XP_011286108 727 LLHGNVNGSKVIIREFQECCRRGLLGKDTGS-PdsssaspPSPGSSRPQTPTssEDAAVPSKARLKRIISENSVYEKRPD 805  domestic cat
Q13111       814 FRMCWYVHPQVLQSFQQEHLPVPCQWSYVTSVPSA---PKEDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDG 890  human
EHB14613     786 FRMCWYVHPQVLHSFNQEHLPVPCQWSYVTMVPSA---PREDSGSVPATLPGQGTPVSVKRKSAGSMCITQFMKKRRHDG 862 
XP_003788927 806 FRMCWYVHPRVLRSFDQEHLPVPCQWSYVTMVPSAprePREDSGGISTTGPSQGIPISLKRKSAGSMCITQFMKKRRHDG 885 
XP_014978011 816 FRMCWYVHPQVLQSFQQEHLPVPCQWSYVTSVPSA---PREDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDG 892 
XP_011286108 806 FRMCWYVHPQVLKSFDQEHLPVPCQWSYVTVVPSA---TREDSGSIPAAGPGQGTPMSLKRKSAGSMCITQFMKKRRHDG 882  domestic cat
Q13111       891 QIGAEDMDGFQADTEEEEEE---EGDCMIVDVPDAAEVQAPCGAASGAGGGVGVDTGKATLTASPLG 954  human
EHB14613     863 QIGVGDMDGFQGDTEEEEEE---DGDCMIMEIPGIGEAQDPCGTTSGAEGAVGMDTSEGPLPTSPLG 926 
XP_003788927 886 QVGAEDMDGFQADTEEEEEEedgDGDCVLMDALDAGEVQAPCGTTSRTGVALGMDTSKSPLPSSPLT 952 
XP_014978011 893 QVGAEDMDGFQADTEEEEEE---EGECMIVDVPDAAEVQAPCGATSGAGGGVGVDTGKAALPASPLG 956 
XP_011286108 883 QVGAGDLDGFQADTEEEEEE---DGDCVILDISDVGEAQAPCGTASGAGGSVGMDSSESPPPASSLG 946  domestic cat
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