Conserved Protein Domain Family
HNF_C

?
pfam09354: HNF_C 
HNF3 C-terminal domain
This presumed domain is found in the C-terminal region of Hepatocyte Nuclear Factor 3 alpha and beta chains. Its specific function is uncertain. The N-terminal region of this presumed domain contains an EH1 (engrailed homology 1) motif, that is characterized by the FxIxxIL sequence.
Statistics
?
PSSM-Id: 430552
Aligned: 11 rows
Threshold Bit Score: 55.3225
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
BAB16313     443 PHPFSISSLMnVTDhqQQ---------Hyqq----hphHQTytpakDLRAYQDAVQ-YynNGMNSltglmpppvndsvpa 508
XP_006003523 342 SHPFSITHLM-SSE--QQ---------Y----------QKM-----DLRSYEQMAH-Y--PNYGS--------------- 376
EEN69167     369 HHPFSINSII-SQD------------------------HKLt----ELKGYDPMQY----SGYASmyn------------ 403
XP_008101045 408 NHPFSINNLMsSSEqqQQ--------------------QKL-----DFKAYEQALQ-YssSSYGA--------------- 446
XP_005989222 363 NHPFSINNLMsSSE--QQ---------Q----------HKL-----DFKAYEQALQ-Y--SSYGP--------------- 398
Q8AWH1       353 NHPFSINNLMsSSE--QQ--------------------HKL-----DFKAYEQALQqY--SSYSG--------------- 388 tropical clawed...
XP_006009988 355 NHPFSINNLM-SSE--QQ---------H----------HKM-----DLKAYEQVMH-Y--SGYGS--------------- 389
XP_005422710  96 NHPFSINNLMsSSE--QQ---------HhhphhqhhhpHKM-----DLKAYEQVMH-Y--SGYAS--------------- 141
CAG09884     324 NHPFSINNLM-SSE--QQ---------Hh---------HKM-----DLKTYEQVMH-Y--SGYGS--------------- 359
XP_006626196 338 NHPFSINNLM-SSE--QQ---------H----------HKM-----DLKTYEQVMH-Y--SGYGS--------------- 372 spotted gar
EHB18836     209 NHPFSINNLM-SSE--QQhhhshhhhqP----------HKM-----DLKAYEQVMH-Y--PGYGS--------------- 252 naked mole-rat
BAB16313     509 qcTIASsGSpvnsassSSVSTPSPSSSS----STSHYS 542
XP_006003523 377 --AVAN-DL-------SPLANKNGLEMPaiscEGNYYT 404
EEN69167     404 -------------tnpSVVPKQEMETPAstepATGYFS 428
XP_008101045 447 --G----GLplggggaSSVGGRGGIEPSa--lEPSYYQ 476
XP_005989222 399 --NLSA-SLpl---gsASMGGRSNIEPSa--lEPSYYQ 428
Q8AWH1       389 --GLP--GMpl---gsPSMAGRGSIEPSa--lEPTYYQ 417 tropical clawed frog
XP_006009988 390 --PMPG-GLs-----mSSVATKTGLE-SpisnDTSYYQ 418
XP_005422710 142 --PVPA-GLa-----mAPVTNKSALEASplagETSYYQ 171
CAG09884     360 --PMAG-ALs-----mGSMAGKHGLDSAsi-pDTAYYQ 388
XP_006626196 373 --PMTG-ALs-----mGSMTSKGGLETSpistDTSYYQ 402 spotted gar
EHB18836     253 --PMPG-SLa-----mGPVTNKAGLDASplaaDTSYYQ 282 naked mole-rat
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap