3HDI,6GIQ,1HR7,1HR6,4NNZ,6OFT,1Q2L,3E4A,2FGE,3S5M,1Q2L,3E4A


Conserved Protein Domain Family
Peptidase_M16_C

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pfam05193: Peptidase_M16_C 
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Peptidase M16 inactive domain
Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp.
Statistics
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PSSM-Id: 428362
Aligned: 131 rows
Threshold Bit Score: 49.6987
Created: 22-Mar-2022
Updated: 13-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3HDI_B  165 SFNEGMLRHYMDRFYTGDYVVISVAG-NVHD-ELIDKIKETFSQVK---------------------------------- 208  Alkalihalobacillus ...
6OFT_B  180 TVTPAQLRQFYQRWYQPNNMTFIVVGdIDSK-EALALIKDNLSKLPan-------------------------------- 226  Escherichia coli K-12
P45181  205 TISAKRVADFYHKWYRPDNMSVIIVGdIDTK-QVVKLLKQNLSQENpi-------------------------------- 251  Haemophilus influen...
Q9CML5  205 TISRQRVADFYHKWYRADNMAVIIVGdIDAQ-QVTSQLKAQIGSINsh-------------------------------- 251  Pasteurella multocida
Q9FIH8  360 KWDVDKIRKFHERWYFPANATLYIVGdIDNIpRIVHNIEAVFGKNGldnestpsspspgafgamanflvpklpaglggtf 439  thale cress
P37648  199 PVEAEKIKDFYQKWYTPDAMTLLVVGnVDAR-SVVDQINKTFGELKg--------------------------------- 244  Escherichia coli K-12
O51486  206 SFQPEDFKKFYRKWYRPELASVIVVGdIDPI-EIEEKIKKQFVSWKn--------------------------------- 251  Lyme disease spiroc...
Q9KRD3  199 AATPDSLKAFYQQWYQPQLAELVITGnFTLE-QGQQWVENYFSSWKkgstekp--------------------------- 250  Vibrio cholerae
Q97LA3  174 KMEFQSVKSFHDKWYKPQNSAICICGdIANS-DIENKISKYFSEFKn--------------------------------- 219  Clostridium acetobu...
O84812  225 SVTTQDMQTWFATHYSPENMAAIVYTtAPLD-TAVPYIASLFSEIPisa------------------------------- 272  Chlamydia trachomatis
3HDI_B  209 ------------------------PTTYNYQGEKpmFLPNRIVRKKET--E---QAHLCLGYPGLPI--------GDKDV 251  Alkalihalobacillus ...
6OFT_B  227 -----------------------kAAENRVWPTKa-ENHLRFNIINDKenRv-nGIALYYRLPMVQV--------NDEQS 273  Escherichia coli K-12
P45181  252 -----------------------tKTTLEKIDFNipLINKWRLDSISE--QgttIPSIELSFFENTIe------tNTLAS 300  Haemophilus influen...
Q9CML5  252 -----------------------sTSPLPPIDFSipFVNQWRVAGISE--KgtyIPTLELSFFEKFTe------qNTLAA 300  Pasteurella multocida
Q9FIH8  440 snektntadqskmikrerhairppVEHNWSLPGTsvDLKPPQIFKHEL--Lq-nFAINMFCKIPVSKv-------QTFGD 509  thale cress
P37648  245 ------------------------KRETPAPVPTlsPLRAEAVSIMTD--Av-rQDRLSIMWDTPWQ----------PIR 287  Escherichia coli K-12
O51486  252 ------------------------PTDKIKEVKVslDVELKDKFLLLE--Dl-eVGEPSLMFFKKEIinfvktkdDLLNA 304  Lyme disease spiroc...
Q9KRD3  251 ------------------------------asiyhqALNNQDLVAPVT--Ag-eSPSLTLIFPQGSAaik---dyASQQE 294  Vibrio cholerae
Q97LA3  220 -----------------------dNEKIEKYSTNycPYGEKVVVNNNV--Nk-nEVKAQFYYLKKDY----------KYS 263  Clostridium acetobu...
O84812  273 ---------------------qytPQKPFPKTQD--TTALNKLFINKA--Ve-pSPQLAIYWHFYDA--------PQSLQ 318  Chlamydia trachomatis
3HDI_B  252 YALVLLNNVLGGSMSSRLFQDIREKRGL--CYSVFSY-HSSFR------DSGMLTIYAGTGHD---QLDDLVYSIQETTS 319  Alkalihalobacillus ...
6OFT_B  274 FIEQAEWSMLVQLFNQRLQERIQ-SGELktISGGTARsVKIAP------DYQSLFFRVNARDD---NMQDAANALMAELA 343  Escherichia coli K-12
P45181  301 YKQELIQQITTRLLNLRLQQWEKETENG--VDSANFYrTHlgk----etLQSIFSLQLIDT-----QYSKTIDKLFAFIA 369  Haemophilus influen...
Q9CML5  301 YKQDLTQQILIRLINLRLQDWEQVKQQK--VESANFYrTHlgk----etLQNIFLLQLFDT-----DYQKATQSLFQFIA 369  Pasteurella multocida
Q9FIH8  510 LRNVLMKRIFLSALHFRINTRYK-SSNp-pFTSVELDhSDSGRe-----GCTVTTLTVTAEPQ---NWQNAVKVAVQEVR 579  thale cress
P37648  288 ESAALLRYWRADLAREALFWHVQQALSAsnSKDIGLG-FDcrv----lyLRAQCAINIESPND---KLNSNLNLVARELA 359  Escherichia coli K-12
O51486  305 IKKSLLAALFENR-----FSELK-TAGVkqFKNVSNKdFFSFKsdnntiVAKSISLNFNPD-----HLNEGIQDFFYELE 373  Lyme disease spiroc...
Q9KRD3  295 FWRDDVGEQLLHT---RLVAAFNDAAQA--ITGIYAT-HYEIE------GQRYTLISVGFAAE---QREKVQALLLETLA 359  Vibrio cholerae
Q97LA3  264 LKSDTIEYFLFSIIKNYILDLFTDKSFG--IVEFYSKvFLHNL--------KLNVLEFKSQSE----FVErLEFIIDSIN 329  Clostridium acetobu...
O84812  319 GWAQSLISILSSEKENSLVALLK-KEQL--ITEMEAE-LYSTSh-----NTQDFEILYKLTNKgerEYQRVLQLTFAFLD 389  Chlamydia trachomatis
3HDI_B  320 ALAEKgLTEKELENGKEQL 338  Alkalihalobacillus halodurans C-125
6OFT_B  344 TIDQHgFSAEELDDVKSTR 362  Escherichia coli K-12
P45181  370 SIKQQgFTQNELSGEIKRL 388  Haemophilus influenzae Rd KW20
Q9CML5  370 EIQQHgFSAQEFQQEKARL 388  Pasteurella multocida
Q9FIH8  580 RLKEFgVTRGELTRYMDAL 598  thale cress
P37648  360 KVRDKgLPEEEFNALVAQK 378  Escherichia coli K-12
O51486  374 RIRKFgFTQGELEKVRSQF 392  Lyme disease spirochete
Q9KRD3  360 SMRDYgVTKNELDIILRGY 378  Vibrio cholerae
Q97LA3  330 KIQAKgINENDFVKYKRIF 348  Clostridium acetobutylicum
O84812  390 YVRHErLPAYSLPEIQKIN 408  Chlamydia trachomatis
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