1LSH_A       2 FQPGKVYRYSYDAFSIS-GLPEP---GVNRAGLSGEMKIEIHGHTHN-------QATLKITQVNLKYFLGP------WP- 63   silver lamprey
Q9NDS1      42 YQPEKTYTYQYSGKSRV-QLKGV---DDGVSETEWAARVDLTWISPC-------DVAISFNNMKMDG--A---------- 98   Marsupenaeus jap...
Q9GSG2      42 YQPGKTYTYEYSGKSRI-QLKGV---EGGLTETDWSAQVELSWITPC-------DMVITMKDSKTDG--A---------- 98   Cherax quadricar...
Q9VLA0      87 NYGEQLYKYQYTVAVRT-EFAGs---GDNSSDLLLKSDLEIFFPKPC-------EgYLRINDAKLYDTLDElndnesDS- 154  fruit fly
AAB04636    46 FKHLRKYTYNYEAESSS-GVPGt---ADSRSATRINCKVELEVPQLC-------SFILKTSQCTLKEVYGFnp----eG- 109  human
Q9U785      35 pKAQSTYVYSLDAKTVL-TPRD-----SQK--VTIKADAEVAIVSSC-------EAVLRLQNVAIDGVPN---------- 89   Euroglyphus maynei
Q9VIH3      38 FKLQNQVILQELGRDSS-SAET-----SYT----FETDLKINSVWSG-------D-EDQLLEVFISGSK----------- 88   fruit fly
Q25490      39 FAAGQKYNYGVEGTVSV-YLTGA---DNQETSLKMLGQASVSAISNC-------ELELSVHNMVLSGPDG---------- 97   tobacco hornworm
NP_524634   43 YIPGNYYDYSFDSILTI-GASSDvpnDSDDTSLKVSGSAKIFAKGNC-------GYTLQLSSVKVTNT------------ 102  fruit fly
P55158      28 LNNERLYKLTYSTEVFLdGGKGK---LKDSVGYRISSDVDVVLLWRNpdgdddqLIQVTITAVNVENVNQQ------RGe 98   golden hamster

1LSH_A      64 SDSFYPLTGGY---DHFIQQL--------------------EVPVRFDy-SAGRIGd-IYAPPQVTDTAVNIVRGILNLF 118  silver lamprey
Q9NDS1      99 ------RGPIA---ARTLERH--------------------PLVVAVV--DGRV-Qh-VCAHPDDEPWAINLKKGVASAF 145  Marsupenaeus jap...
Q9GSG2      99 ------TVPGA---SRFLERY--------------------PLVVAVT--DGKV-Hh-VCSHPDDDTWSINLKKGVASAF 145  Cherax quadricar...
Q9VLA0     155 SEKTKEYDYYD---NLANEESesqnydnmhpkssdfnvdltKNLLRFAf-HDGLISe-VCPQEQETPWVLNIKKGILSAF 229  fruit fly
AAB04636   110 KALLKKTKNSE---EFAAAMS--------------------RYELKLAi-PEGK-QvfLYPEKDEPTYILNIKRGIISAL 164  human
Q9U785      90 -----GAELAA---ELAAKS----------------------FAFGYF--NGRILG--VCPANDDQDWSLNVKKAIVSAL 135  Euroglyphus maynei
Q9VIH3      89 -----VDASGK---ARSITRIp-------------------DRPFYISl-VRGQPDk-VIAHTSKDQSLLNLERGIASLL 139  fruit fly
Q25490      98 ------KKYPC---PQGIE-----------------------KPVRFSyqDGRVGPe-ICAAEDDSRRSLNIKRAIISLL 144  tobacco hornworm
NP_524634  103 ------KESVE---KKILNSI--------------------QKPVQFTl-VSGILEpqICSDSSDLDYSLNIKRAVVSLL 152  fruit fly
P55158      99 KSIFKGKTTPKiigKDNLEAL--------------------QRPVLLHl-VRGKVKe-FYSYENEPVGIENLKRGLASLF 156  golden hamster

1LSH_A     119 QLSLKKNQQ---TFELQETGVEGICQTTYVVQEGYRTNEMA-VVKTKDLNNCDHK--VYKTMG-TAYAErCPTCQKMNKN 191  silver lamprey
Q9NDS1     146 QNSIPSLSTvssGMTVTETDVVGKCPTTYQIETEGEK---ViVVKEKNHRHCQQR--YPTPAEtPAPWLkAP-----LPI 215  Marsupenaeus jap...
Q9GSG2     146 QNSLPSNSTinsGQNITETDVVGKCPTRYEVQDHGDT---ViMIKEKNHRQCKER--YHTPAEnPAPWLrGP-----FIT 215  Cherax quadricar...
Q9VLA0     230 QNTMMRFDVda---nTTETDVSGQCQVQYALEDTDSSYVT--IRKTKDINSCRQR--YATHSVlQTTPYtFRDDKTIWPI 302  fruit fly
AAB04636   165 LVPPETEEAk---QVLFLDTVYGNCSTHFTVKTRKGNVATe-ISTERDLGQCDRF--KPIRTGiSPLALiKGMTRPLSTL 238  human
Q9U785     136 QVQFDENKD-----KVEETDFSGTCPTEYRKIRSDDDNT-VvMEKRKDLNLCDDRrvDLRQTPdQALGQlKEIIRHYMHP 209  Euroglyphus maynei
Q9VIH3     140 QLRLDASQE-------EELDVSGLCRVSYNVKSSTKVEKTk-RDCSLWDLRVNYNpeEALGVTqQAQETvFYELSSEGTL 211  fruit fly
Q25490     145 QAEQKPS---------VQVDVFGVCPTEVSSSQEGGAVLLH---RSRDLSRCAHR--EQGRNDfVNSIAnPDAGIKDLQV 210  tobacco hornworm
NP_524634  153 QSGIEAEH---------EVDVFGMCPTHTSTSKVGNANi---ITKARNLNSCSHR--EQINSGlVSGKVnEKAGITSSLL 218  fruit fly
P55158     157 QMQLSSG-------TTNEVDISGDCKVTYQAQQDK-------VVKTKALDTCKIE-----RSGfTTVNQvLGVSS----- 212  golden hamster

1LSH_A     192 LRSTAVYNYAIFDEpsGYIIKSAHSEEIQQLSVFDIKEGNV-VIESRQKLILEGIQSAP--AASQAASL--Q--NRGGLM 264  silver lamprey
Q9NDS1     216 EESKSECKQEITNG-----IYTSIMCHDKNIVRPAIGIYKYvEANQESTLHFISETTDTsaITAIPRGE--M--HIESLL 286  Marsupenaeus jap...
Q9GSG2     216 DESTCMCKQETRNG-----IYSAITCEDKNVVKPSYGAYKYvEAKMMSTLKYLSESSEHs--SDILEGN--M--VRKSLL 284  Cherax quadricar...
Q9VLA0     303 LKSQSHCNLTIDNN-----VYKEIKCLETHLLVPFSNASSGaLTTSTSRLKLDGVESYSagEFLEQNPElvE--RRATLV 375  fruit fly
AAB04636   239 ISSSQSCQYTLDAK--RKHVAEAICKEQHLFLPFSYKNKYGmVAQVTQTLKLEDTPKIN---SRFFGEG--T--KKMGLA 309  human
Q9U785     210 MDSDLMCRMTLKDK-----VVSEVDCEERHVLVHRSHKP---IHLSYVKMMLKQSKDGVaaDLGQTDSE--P--KRPYLS 277  Euroglyphus maynei
Q9VIH3     212 LHAESQENHRLN--------LAAKPDVGSFVKSSLILQHVSqGSEEVKQLQLGSLDK-----AIQS-----L--LEWYRV 271  fruit fly
Q25490     211 LQSMLNVESKVNNG-----VPEKVSAIEEYLYKPFSVGENGaRAKVHTKLTL-SGKGGA--GGGNAHCT--E--SRSIIF 278  tobacco hornworm
NP_524634  219 LQANYIKESRIVN-----HLIENVQLTETYKFIGNTKRNSDiSAKVVTILKLKNPSGTK---ANSPGTG--S--TVRSLI 286  fruit fly
P55158     213 -KATSVTTYKIEDS-----FVTAVHAEETRDFSLNFLQAIAgKIVSKQKLELKTTEAGP---RMVPGKQ--VagVIKALD 281  golden hamster

1LSH_A     265 YKFPS-SAITKMSSLFvtKG--K-NLESEIHTVLKHLVENNQLSVHED-APAKFLRLTAFLRNVDAGVLQSIWHKLHQ-Q 338  silver lamprey
Q9NDS1     287 YNHET----------M--KD--P-ELAPELDQLMKEICEKTKDTVEAe-aAALVAKALHLLRRVPETVVVEIAQKVRQgH 350  Marsupenaeus jap...
Q9GSG2     285 YDYHT-P--------K--KD--P-SMVTQLDRIMSQICRKTRDNVERd-vAALVARAIQFLRMVPEEAVEQTLNKIRSgQ 349  Cherax quadricar...
Q9VLA0     376 FDHTP---------AV--KP--ShDEIKAARELLVEMCRVGFPNIQRe-FIDVFTNFLQTSKSLDYKTLSVLLQRSASt- 440  fruit fly
AAB04636   310 FESTK-S--------T--SP--P-KQAEAVLKTLQELKKLTISEQNIq-rANLFNKLVTELRGLSDEAVTSLLPQLIEvS 374  human
Q9U785     278 FDHKH-Kn----------------PTETDVVQVLKKLCTEITEPQASieTSFTFHKLVDKLRYLSAEETATVDESVKTaI 340  Euroglyphus maynei
Q9VIH3     272 FELES-Dvd-gMISAI--KE--Q-TLEDQLKASLTELQSADVGKSS---LALAYVKLIPLARITRQEQFEDLLTEHAEvL 341  fruit fly
Q25490     279 DVPHG-TS----------SA--S-GNLNSVISAVKETARTVANDASSK-SAGQFAQLVRIMRTSSKDDLMRIYSQVKAh- 342  tobacco hornworm
NP_524634  287 FQRPE-TY-----------T--S-KNINALKTILSDLVDSTGDYVKKE-TAKKFVEFIRLLRQSDSETLLELAAFPHPn- 349  fruit fly
P55158     282 SKYTAiPIVGQVLQSA--CQgcP-SLAEHWQSIRKHLEPENLSNAK---AVSSFLAFIQHLRTARREEILQILK--AEk- 352  golden hamster

1LSH_A     339 -----KDYRRWILDAVPAMATSEALLFLKRTLASEQLTSAEATQIVA-STLSN-QQATRESLSYARELLNTSFIRNRPIL 411  silver lamprey
Q9NDS1     351 ycsdsAKLESIFLDAVAFLHESGAVKVMVQEILNGRAT-GGRLALYT-AALYLtPRPNIEAVKALTPLFESPRPMPSLLL 428  Marsupenaeus jap...
Q9GSG2     350 ycqdyKKLEELFLDFVSFVDEPGAVKVMVKELLNSRFT-RGRYSLYT-AAFYLiPRPCIHAMKALKPLFESTRPMPYPTL 427  Cherax quadricar...
Q9VLA0     441 ----cEQGRNHLLESLPFIGSTASYKVMQTLETFHSILEYAKNRLDA-EYTLGaTAVVHSFCKHHEACEENLRVQQIINL 515  fruit fly
AAB04636   375 --------SPITLQALVQCGQPQCSTHILQWLKR-VHANPLLIDVVT-YLVALiPEPSAQQLREIFNMARDQRSRATLYA 444  human
Q9U785     341 cpahaKRIRELFLDASAFAASDGSIRTLVKAHENQELS-VTRSTALF-TVAAIkAAPNKETVNVLLPVIASEKTIRPMLL 418  Euroglyphus maynei
Q9VIH3     342 p-----QLVDLLGAVQTFDAHNATFGFLYKESET-TSEQLDLLEKYL-QSLAVaTHPDRKIVEHLFGLLEQESIKKHLKL 414  fruit fly
Q25490     343 -----QLEKRVYLDALLRAGTGESIEASIQILKSKDLSQLE-QHLVF-LSLGNaRHVNNPALKAAAGLLDMPNLPKEVYL 415  tobacco hornworm
NP_524634  350 ----kVLARKVYLDGLFRTSTAESARVILKQLSKFD----EKEKLLAiLSLNIvKSVDKETLNQAAS-QLLPNAPKELYI 420  fruit fly
P55158     353 -----KEVLPQLVDAVTSAQTPDSLEAILDFLDFKSDSSIVLQERFL-YACGFaSHPDEELLRAL--LSKFKGSFASNDI 424  golden hamster

1LSH_A     412 RKTAVLGYGSLVFRYC--ANTVScpD----ELLQPLHDLLSQSS--D--RA--KEEEIVLALKALGNAGQPNSIKKIQRF 479  silver lamprey
Q9NDS1     429 AAASMVNHYCRHTPHC--HQEAp-vEriaeILAAKVEGHCSPSI--G--VE--EKEEALAIFKALGNMGVVTPAVTRAAA 499  Marsupenaeus jap...
Q9GSG2     428 AASSMVNNYCNHNRNC--HEEEp-vKslaeTLGNKLQRQCSASE--D--EQ--TVQAALTTLKALGNMGVMTPAVATSVL 498  Cherax quadricar...
Q9VLA0     516 LETEFLNLYNLFKg--------------------------------E--RR--TRERMVILLKGLGNIGVVSSAFAEQLQ 559  fruit fly
AAB04636   445 LSHAVNNYHKTNPTGT--QELLD--------IANYLMEQIQDD---C--TG--DEDYTYLILRVIGNMGQTMEQLTPELK 507  human
Q9U785     419 GFSVLVRRYCEKSADC--ASNSGv-----kDARDAYLARLAVAKdpS--ER--MTIVRALENLNVNTEDVDNMINAMDEI 487  Euroglyphus maynei
Q9VIH3     415 RESVIQTVATLTRQSGldVEDP---------LLKEVRSYLLQG-------L--TSKEPTLYIRALQNLQDPATIEALLEH 476  fruit fly
Q25490     416 GAGALGGAYCREH-DC--HNVKPeg---ivALSNKLGSKLQNCR--P--KNkpDEDVVVAILKGIRNIRHLEDSLIDKLV 485  tobacco hornworm
NP_524634  421 AVGNLVAKYCLKN-YC--QGPEi------dAISKKFSDGLKHCK--PntKR--EEERIVYILKGLGNAKSLSGNTVAALS 487  fruit fly
P55158     425 RETVMIIIGALVRKLC--QNE----GcklkAVVEAKKLILGGLE--K--PE--KKEDTTMYLLALKNALLPEGIPLLLKY 492  golden hamster

1LSH_A     480 LP-----G-QgkslDEYSTRVQAEAIMALRNIAKRDPRKVQEIVLPIFLNVAIKSE--LRIRSCIVFFESKPSVALVSMV 551  silver lamprey
Q9NDS1     500 QCi-----eK----EGLETSIRVAAAQAFR-QAN-CDRPAVQKLVDIATRPTFETE--VRIASYLAAIRC-AEKEHLEQI 565  Marsupenaeus jap...
Q9GSG2     499 RCm-----gT----EGADNRIRVAAAQAFR-KAK-CHRASTGRLVGYALDSRKTTE--VRIASYIAAVRC-AEKWDFEKI 564  Cherax quadricar...
Q9VLA0     560 WIi-----rE----DEAPVDIRLHGILAFR---RVDCARHRSYFLDNYGNYTLNSE--LRIYSYLQAMRC-PDYISVGVI 624  fruit fly
AAB04636   508 SSilkcvQ-S----TKPSLMIQKAAIQALR--KMEPKDKDQEVLLQTFLDDASPGD--KRLAAYLMLMRS-PSQADINKI 577  human
Q9U785     488 IK-------S----TDAEPSLRAAAVNALP-----SDASHMDRYKSLVMDESMPNE--ARIAAFHKMMQN----GGMTHI 545  Euroglyphus maynei
Q9VIH3     477 AQt-----gE----APNLSVAALQALKAFPLGSFNSSHRLQFESIFYQRKRRFDSS--ARTLALDIILSLRPTQEQLGNF 545  fruit fly
Q25490     486 HC-----AvD----NNVKARVRAVALEAF--HADPCSAKIHKTAMDIMKNRQLDSE--IRIKAYLAVIEC-PCSHSASEI 551  tobacco hornworm
NP_524634  488 EC-----A-S----TGRSNRIRVAALHAFSKV--KCEETLQSKSLELLKNRNEDSE--LRIEAYLSAISC-PNAEVANQI 552  fruit fly
P55158     493 AE-----A-G----EGPVSHLATTVLQRYD--VSFITDEVKKTLNRIYHQNRKIHEktVRTTAAAVILKSNPSYMDVKNI 560  golden hamster

1LSH_A     552 AVRLRREP-NLQVASFVYSQMR 572  silver lamprey
Q9NDS1     566 IEKISEEE-NTQVRGFVLGHLI 586  Marsupenaeus japonicus
Q9GSG2     565 VEKISVGQ-NTQVRGFILSHLR 585  Cherax quadricarinatus
Q9VLA0     625 KSILEHEE-INQVGSFVWSHLT 645  fruit fly
AAB04636   578 VQILPWEQ-NEQVKNFVASHIA 598  human
Q9U785     546 KDLFAVKG--DCMKNYVLTYVD 565  Euroglyphus maynei
Q9VIH3     546 LDYLASNDrQFEIKTYVLQKLR 567  fruit fly
Q25490     552 KNLLDSEP-VHQVGNFITSSLR 572  tobacco hornworm
NP_524634  553 SEIVNSET-VNQVGGFISSNLK 573  fruit fly
P55158     561 LLSIGELP--KEMNKYMLTFVR 580  golden hamster