- AIS
Abbreviated Injury Score
- CAG
Confidentiality Advisory Group
- CRF
case report form
- CTU
Clinical Trials Unit
- DMC
Data Monitoring Committee
- EQ-5D-5L
EuroQol-5 Dimensions, five-level version
- FFP
fresh-frozen plasma
- GOS
Glasgow Outcome Scale
- HTA
Health Technology Assessment
- HDU
high-dependency unit
- ICU
intensive care unit
- ISS
Injury Severity Score
- ITT
intention to treat
- MHP
major haemorrhage protocol
- NIHR
National Institute for Health and Care Research
- PAIR
Patient/Public Advisors for Injury Research
- PPI
patient and public involvement
- PPIE
patient and public involvement and experience
- QALY
quality-adjusted life-year
- RBC
red blood cell
- SAP
statistical analysis plan
- TARN
Trauma Audit and Research Network
- TIC
trauma-induced coagulopathy
- TMG
Trial Management Group
- TSC
Trial Steering Committee
Publication Details
Copyright
This work was produced by Curry et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.
Publisher
National Institute for Health and Care Research, Southampton (UK)
NLM Citation
Curry N, Davenport R, Thomas H, et al. Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis. Southampton (UK): National Institute for Health and Care Research; 2024 Nov. (Health Technology Assessment, No. 28.76.) List of abbreviations.