List of abbreviations

Nicola Curry; Ross Davenport; Helen Thomas; Erin Fox; Joanne Lucas; Amy Evans; Efthalia Massou; Rupa Sharma; Shaminie Shanmugaranjan; Claire Rourke; Alice Newton; Alison Deary; Nikki Dallas; Chloe Fitzpatrick-Creamer; Jeanette M Podbielski; Charles E Wade; Antoinette Edwards; Jonathan Benger; Stephen Morris; Bryan A Cotton; James Piercy; Laura Green; Karim Brohi; Simon Stanworth

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Curry N, Davenport R, Thomas H, et al. Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis. Southampton (UK): National Institute for Health and Care Research; 2024 Nov. (Health Technology Assessment, No. 28.76.)

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Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis.

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AIS: Abbreviated Injury Score
CAG: Confidentiality Advisory Group
CRF: case report form
CTU: Clinical Trials Unit
DMC: Data Monitoring Committee
EQ-5D-5L: EuroQol-5 Dimensions, five-level version
FFP: fresh-frozen plasma
GOS: Glasgow Outcome Scale
HTA: Health Technology Assessment
HDU: high-dependency unit
ICU: intensive care unit
ISS: Injury Severity Score
ITT: intention to treat
MHP: major haemorrhage protocol
NIHR: National Institute for Health and Care Research
PAIR: Patient/Public Advisors for Injury Research
PPI: patient and public involvement
PPIE: patient and public involvement and experience
QALY: quality-adjusted life-year
RBC: red blood cell
SAP: statistical analysis plan
TARN: Trauma Audit and Research Network
TIC: trauma-induced coagulopathy
TMG: Trial Management Group
TSC: Trial Steering Committee

This work was produced by Curry et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited.

Bookshelf ID: NBK609192

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Curry N, Davenport R, Thomas H, et al. Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis. Southampton (UK): National Institute for Health and Care Research; 2024 Nov. (Health Technology Assessment, No. 28.76.) List of abbreviations.
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