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National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Health Sciences Policy; Forum on Drug Discovery, Development, and Translation; Board on Health Care Services; National Cancer Policy Forum; Nass S, Johnson AF, Zhu J, et al., editors. Addressing Treatment Resistance in the Development of Cancer Immune Modulator Therapeutics: Proceedings of a Workshop. Washington (DC): National Academies Press (US); 2024 Jul 29.

Cover of Addressing Treatment Resistance in the Development of Cancer Immune Modulator Therapeutics

Addressing Treatment Resistance in the Development of Cancer Immune Modulator Therapeutics: Proceedings of a Workshop.

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Acronyms and Abbreviations

AhR

aryl hydrocarbon receptor

AI

artificial intelligence

CAR T

chimeric antigen receptor T cell

CD

cluster of differentiation

COE

contribution of effect

COVID-19

coronavirus disease of 2019

ctDNA

circulating tumor DNA

CTLA-4

cytotoxic T-lymphocyte-associated protein 4

dMMR

deficient mismatch repair

EHR

electronic health record

FDA

U.S. Food and Drug Administration

FNIH

Foundation for the National Institutes of Health

GITR

glucocorticoid-induced tumor-necrosis-factor-related gene

ICI

immune checkpoint inhibitor

IDO1

indoleamine 2,3-dioxygenase-1

irAE

immune-related adverse event

JAK

Janus kinase

LAG-3

lymphocyte activation gene-3

LungMAP

Lung Cancer Master Protocol

mCODE

Minimal Common Oncology Data Elements

ML

machine learning

MRD

minimal residual disease

MRI

magnetic resonance imaging

MSI-H

microsatellite instability-high

NCI

National Cancer Institute

NLP

natural language processing

ORIEN

Oncology Research Information Exchange Network

pCR

pathological complete response

PD-1

programmed cell death receptor 1

PD-L1

programmed cell death ligand 1

PET

positron emission tomography

RECIST

Response Evaluation Criteria in Solid Tumors

RNA

ribonucleic acid

SCNA

somatic copy number alteration

TCR

T-cell receptor

TMB-H

tumor mutational burden-high

Copyright 2024 by the National Academy of Sciences. All rights reserved.
Bookshelf ID: NBK605923

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