This Consensus Study Report was reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise. The purpose of this independent review is to provide candid and critical comments that will assist the National Academies of Sciences, Engineering, and Medicine in making each published report as sound as possible and to ensure that it meets the institutional standards for quality, objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process.

We thank the following individuals for their review of this report:

• BARBARA E. BIERER, Harvard Medical School and Brigham and Women's Hospital
• JULIA GREEN BRODY, Silent Spring Institute
• ELLEN WRIGHT CLAYTON, Vanderbilt University Medical Center
• BARRY S. COLLER, The Rockefeller University
• CRISPIN GOYTIA-VASQUEZ, Mount Sinai Health System
• ALBERTO GUTIERREZ, NDA Partners LLC
• KATHY L. HUDSON, People-Centered Research Foundation
• DEVEN McGRAW, Ciitizen
• J. STEPHEN MIKITA, Spinal Muscular Atrophy Foundation
• ELLEN PETERS, The Ohio State University
• HEIDI REHM, Massachusetts General Hospital
• MARK E. SOBEL, American Society for Investigative Pathology
• SUSAN M. WOLF, University of Minnesota
• BARBARA A. ZEHNBAUER, Emory University School of Medicine
• MARK L. ZEIDEL, Harvard Medical School and Beth Israel Deaconess Medical Center

Although the reviewers listed above provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations of this report nor did they see the final draft before its release. The review of this report was overseen by LYNN R. GOLDMAN, The George Washington University, and JOSHUA M. SHARFSTEIN, Johns Hopkins Bloomberg School of Public Health. They were responsible for making certain that an independent examination of this report was carried out in accordance with the standards of the National Academies and that all review comments were carefully considered. Responsibility for the final content rests entirely with the authoring committee and the National Academies.