TABLE 7

All-cause mortality at 28 days by treatment arm: blunt vs. penetrating injury type

OutcomeBluntPenetrating
Standard care arm (N = 519)Intervention arm (N = 495)Standard care arm (N = 277)Intervention arm (N = 290)
Participants who died on or before day 28 from admission, n/N (%)174/500 (34.8)147/483 (30.4)27/271 (10.0)45/277 (16.2)
 Relative riska (95% CI)0.88 (0.72 to 1.06)1.62 (1.17 to 2.23)
 ORa (95% CI)0.82 (0.62 to 1.09)1.74 (1.20 to 2.51)
 p-value for subgroupa0.16340.0058
 p-value for interaction termb0.0040
Participants for whom 28-day vital status was not available from any source, n/N (%)19/519 (3.7)12/495 (2.4)6/277 (2.2)13/290 (4.5)
a

Intervention arm relative to standard care arm, adjusted for centre.

b

p-value for interaction, adjusted for centre and blunt vs. penetrating injury.

Note

Participants for whom 28-day vital status was not available were not included in this analysis. No participants were excluded for other reasons.

From: Chapter 3, Results

Cover of Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis
Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis.
Health Technology Assessment, No. 28.76.
Curry N, Davenport R, Thomas H, et al.
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