Line graphs showing the cumulative incidence of hypertension, kidney disease, dyslipidemia, nerve disease and any microvascular disease at 15 years follow-up. Cumulative incidence for microvascular disease was 80%.

FIGURE 4.

Diabetes-Related Complications During Long-Term Follow-Up of Patients With Youth-Onset Type 2 Diabetes.

Panel A shows the baseline prevalences and cumulative incidences of hypertension, dyslipidemia (low‑density lipoprotein or triglyceride dyslipidemia), kidney disease, and nerve disease. Panel B shows the baseline prevalence and cumulative incidence of any microvascular complication. The dashed lines in Panels A and B indicate the time when the cumulative incidence reached 50%, and the shaded bands represent 95% confidence intervals. Baseline refers to the time of enrollment in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) clinical trial.

SOURCE: Reference (66). From N Engl J Med, TODAY Study Group, Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P, Long-term complications in youth-onset type 2 diabetes, 385(5), 416-426. Copyright © 2021 Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.

From: Obesity Management for the Treatment of Type 2 Diabetes

Cover of Diabetes in America
Diabetes in America [Internet].
Lawrence JM, Casagrande SS, Herman WH, et al., editors.
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