Graphical depiction of beta cell mass loss over time by corresponding disease stage, indicating that the most significant decline in cell mass is during stage 2, dysglycemia.

FIGURE 7.

Phases in the Natural History of Type 1 Diabetes.

Abs, islet autoantibodies; IA, islet autoimmunity; T1D, type 1 diabetes.

SOURCE: Adapted from reference (210)

From: Genetics of Type 1 Diabetes

Cover of Diabetes in America
Diabetes in America [Internet].
Lawrence JM, Casagrande SS, Herman WH, et al., editors.
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